-
1
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel R, Naishadham D, Jemal A (2012) Cancer statistics, 2012. CA Cancer J Clin 62(1): 10-29.
-
(2012)
CA Cancer J Clin
, vol.62
, Issue.1
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
Tomlins SA, et al. (2005) Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310(5748):644-648. (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
3
-
-
34247363715
-
Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer
-
DOI 10.1038/modpathol.3800769, PII 3800769
-
Mehra R, et al. (2007) Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer. Mod Pathol 20(5):538-544. (Pubitemid 46631996)
-
(2007)
Modern Pathology
, vol.20
, Issue.5
, pp. 538-544
-
-
Mehra, R.1
Tomlins, S.A.2
Shen, R.3
Nadeem, O.4
Wang, L.5
Wei, J.T.6
Pienta, K.J.7
Ghosh, D.8
Rubin, M.A.9
Chinnaiyan, A.M.10
Shah, R.B.11
-
4
-
-
34248510706
-
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort
-
DOI 10.1038/sj.onc.1210237, PII 1210237
-
Demichelis F, et al. (2007) TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene 26(31):4596-4599. (Pubitemid 47037039)
-
(2007)
Oncogene
, vol.26
, Issue.31
, pp. 4596-4599
-
-
Demichelis, F.1
Fall, K.2
Perner, S.3
Andren, O.4
Schmidt, F.5
Setlur, S.R.6
Hoshida, Y.7
Mosquera, J.-M.8
Pawitan, Y.9
Lee, C.10
Adami, H.-O.11
Mucci, L.A.12
Kantoff, P.W.13
Andersson, S.-O.14
Chinnaiyan, A.M.15
Johansson, J.-E.16
Rubin, M.A.17
-
5
-
-
68049131467
-
Reactivation of androgen receptor-regulated tmprss2:erg gene expression in castration-resistant prostate cancer
-
Cai C, Wang H, Xu Y, Chen S, Balk SP (2009) Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer. Cancer Res 69(15):6027-6032.
-
(2009)
Cancer Res
, vol.69
, Issue.15
, pp. 6027-6032
-
-
Cai, C.1
Wang, H.2
Xu, Y.3
Chen, S.4
Balk, S.P.5
-
6
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
DOI 10.1038/nature06024, PII NATURE06024
-
Tomlins SA, et al. (2007) Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 448(7153):595-599. (Pubitemid 47206938)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
Helgeson, B.E.4
Cao, X.5
Morris, D.S.6
Menon, A.7
Jing, X.8
Cao, Q.9
Han, B.10
Yu, J.11
Wang, L.12
Montie, J.E.13
Rubin, M.A.14
Pienta, K.J.15
Roulston, D.16
Shah, R.B.17
Varambally, S.18
Mehra, R.19
Chinnaiyan, A.M.20
more..
-
7
-
-
41149097040
-
A causal role for ERG in neoplastic transformation of prostate epithelium
-
DOI 10.1073/pnas.0711711105
-
Klezovitch O, et al. (2008) A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci USA 105(6):2105-2110. (Pubitemid 351439472)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.6
, pp. 2105-2110
-
-
Klezovitch, O.1
Risk, M.2
Coleman, I.3
Lucas, J.M.4
Null, M.5
True, L.D.6
Nelson, P.S.7
Vasioukhin, V.8
-
9
-
-
66749188650
-
Aberrant erg expression cooperates with loss of pten to promote cancer progression in the prostate
-
Carver BS, et al. (2009) Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat Genet 41(5):619-624.
-
(2009)
Nat Genet
, vol.41
, Issue.5
, pp. 619-624
-
-
Carver, B.S.1
-
10
-
-
68149159298
-
Ets family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells
-
Zong Y, et al. (2009) ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells. Proc Natl Acad Sci USA 106(30):12465-12470.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.30
, pp. 12465-12470
-
-
Zong, Y.1
-
11
-
-
66149098947
-
Characterization of erg, ar and pten gene status in circulating tumor cells from patients with castration-resistant prostate cancer
-
Attard G, et al. (2009) Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer. Cancer Res 69(7): 2912-2918.
-
(2009)
Cancer Res
, vol.69
, Issue.7
, pp. 2912-2918
-
-
Attard, G.1
-
12
-
-
84882285291
-
Ets factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to pten loss
-
Chen Y, et al. (2013) ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss. Nat Med 19(8):1023-1029.
-
(2013)
Nat Med
, vol.19
, Issue.8
, pp. 1023-1029
-
-
Chen, Y.1
-
13
-
-
84862161257
-
A transcriptional repressor co-regulatory network governing androgen response in prostate cancers
-
Chng KR, et al. (2012) A transcriptional repressor co-regulatory network governing androgen response in prostate cancers. EMBO J 31(12):2810-2823.
-
(2012)
EMBO J
, vol.31
, Issue.12
, pp. 2810-2823
-
-
Chng, K.R.1
-
14
-
-
77952103123
-
An integrated network of androgen receptor, polycomb, and tmprss2-erg gene fusions in prostate cancer progression
-
Yu J, et al. (2010) An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 17(5):443-454.
-
(2010)
Cancer Cell
, vol.17
, Issue.5
, pp. 443-454
-
-
Yu, J.1
-
15
-
-
14444268087
-
The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme
-
DOI 10.1083/jcb.142.4.1053
-
Taya S, et al. (1998) The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme. J Cell Biol 142(4):1053-1062. (Pubitemid 28402059)
-
(1998)
Journal of Cell Biology
, vol.142
, Issue.4
, pp. 1053-1062
-
-
Taya, S.1
Yamamoto, T.2
Kano, K.3
Kawano, Y.4
Iwamatsu, A.5
Tsuchiya, T.6
Tanaka, K.7
Kanai-Azuma, M.8
Wood, S.A.9
Mattick, J.S.10
Kaibuchi, K.11
-
16
-
-
73849083434
-
Deubiquitinase usp9x stabilizes mcl1 and promotes tumour cell survival
-
Schwickart M, et al. (2010) Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival. Nature 463(7277):103-107.
-
(2010)
Nature
, vol.463
, Issue.7277
, pp. 103-107
-
-
Schwickart, M.1
-
17
-
-
34147155353
-
Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells
-
DOI 10.1182/blood-2006-02-005579
-
Bartholomeusz GA, et al. (2007) Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells. Blood 109(8): 3470-3478. (Pubitemid 46572537)
-
(2007)
Blood
, vol.109
, Issue.8
, pp. 3470-3478
-
-
Bartholomeusz, G.A.1
Talpaz, M.2
Kapuria, V.3
Ling, Y.K.4
Wang, S.5
Estrov, Z.6
Priebe, W.7
Wu, J.8
Donato, N.J.9
-
18
-
-
78549247880
-
Deubiquitinase inhibition by small-molecule wp1130 triggers aggresome formation and tumor cell apoptosis
-
Kapuria V, et al. (2010) Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis. Cancer Res 70(22):9265-9276.
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 9265-9276
-
-
Kapuria, V.1
-
19
-
-
79953072934
-
Bcr-abl ubiquitination and usp9x inhibition block kinase signaling and promote cml cell apoptosis
-
Sun H, et al. (2011) Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. Blood 117(11):3151-3162.
-
(2011)
Blood
, vol.117
, Issue.11
, pp. 3151-3162
-
-
Sun, H.1
-
20
-
-
84881612540
-
Ex vivo culture of human prostate tissue and drug development
-
Centenera MM, Raj GV, Knudsen KE, Tilley WD, Butler LM (2013) Ex vivo culture of human prostate tissue and drug development. Nat Rev Urol 10(8):483-487.
-
(2013)
Nat Rev Urol
, vol.10
, Issue.8
, pp. 483-487
-
-
Centenera, M.M.1
Raj, G.V.2
Knudsen, K.E.3
Tilley, W.D.4
Butler, L.M.5
-
21
-
-
79955968629
-
Mechanistic rationale for inhibition of poly(adp-ribose) polymerase in ets gene fusion-positive prostate cancer
-
Brenner JC, et al. (2011) Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell 19(5):664-678.
-
(2011)
Cancer Cell
, vol.19
, Issue.5
, pp. 664-678
-
-
Brenner, J.C.1
-
22
-
-
80054755085
-
Oncogenic ets proteins mimic activated ras/mapk signaling in prostate cells
-
Hollenhorst PC, et al. (2011) Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes Dev 25(20):2147-2157.
-
(2011)
Genes Dev
, vol.25
, Issue.20
, pp. 2147-2157
-
-
Hollenhorst, P.C.1
-
23
-
-
84871200741
-
Highly specific targeting of the tmprss2/erg fusion gene using liposomal nanovectors
-
Shao L, et al. (2012) Highly specific targeting of the TMPRSS2/ERG fusion gene using liposomal nanovectors. Clin Cancer Res 18(24):6648-6657.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.24
, pp. 6648-6657
-
-
Shao, L.1
-
24
-
-
70449420043
-
Adamts1, a putative anti-angiogenic factor, is decreased in human prostate cancer
-
Gustavsson H, Wang W, Jennbacken K, Welén K, Damber JE (2009) ADAMTS1, a putative anti-angiogenic factor, is decreased in human prostate cancer. BJU Int 104(11): 1786-1790.
-
(2009)
BJU Int
, vol.104
, Issue.11
, pp. 1786-1790
-
-
Gustavsson, H.1
Wang, W.2
Jennbacken, K.3
Welén, K.4
Damber, J.E.5
-
25
-
-
81255150464
-
Androgen receptor variants occur frequently in castration resistant prostate cancer metastases
-
Zhang X, et al. (2011) Androgen receptor variants occur frequently in castration resistant prostate cancer metastases. PLoS ONE 6(11):e27970.
-
(2011)
PLoS ONE
, vol.6
, Issue.11
-
-
Zhang, X.1
|