-
1
-
-
84884950975
-
Long-term cognitive impairment after critical illness
-
BRAIN-ICU Study Investigators
-
Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, et al.; BRAIN-ICU Study Investigators. Long-term cognitive impairment after critical illness. N Engl J Med 2013;369:1306-1316.
-
(2013)
N Engl J Med
, vol.369
, pp. 1306-1316
-
-
Pandharipande, P.P.1
Girard, T.D.2
Jackson, J.C.3
Morandi, A.4
Thompson, J.L.5
Pun, B.T.6
Brummel, N.E.7
Hughes, C.G.8
Vasilevskis, E.E.9
Shintani, A.K.10
-
2
-
-
78650305502
-
Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients
-
SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group
-
Shehabi Y, Riker RR, Bokesch PM, Wisemandle W, Shintani A, Ely EW; SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group. Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients. Crit Care Med 2010;38:2311-2318.
-
(2010)
Crit Care Med
, vol.38
, pp. 2311-2318
-
-
Shehabi, Y.1
Riker, R.R.2
Bokesch, P.M.3
Wisemandle, W.4
Shintani, A.5
Ely, E.W.6
-
3
-
-
1842867052
-
Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit
-
Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE Jr, Inouye SK, Bernard GR, Dittus RS. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004;291:1753-1762.
-
(2004)
JAMA
, vol.291
, pp. 1753-1762
-
-
Ely, E.W.1
Shintani, A.2
Truman, B.3
Speroff, T.4
Gordon, S.M.5
Harrell Jr., F.E.6
Inouye, S.K.7
Bernard, G.R.8
Dittus, R.S.9
-
4
-
-
72749113044
-
Days of delirium are associated with 1-year mortality in an older intensive care unit population
-
Pisani MA, Kong SY, Kasl SV, Murphy TE, Araujo KL, Van Ness PH. Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care Med 2009;180: 1092-1097.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 1092-1097
-
-
Pisani, M.A.1
Kong, S.Y.2
Kasl, S.V.3
Murphy, T.E.4
Araujo, K.L.5
Van Ness, P.H.6
-
5
-
-
77955499601
-
One-year trajectories of care and resource utilization for recipients of prolonged mechanical ventilation: A cohort study
-
Unroe M, Kahn JM, Carson SS, Govert JA, Martinu T, Sathy SJ, Clay AS, Chia J, Gray A, Tulsky JA, et al. One-year trajectories of care and resource utilization for recipients of prolonged mechanical ventilation: A cohort study. Ann Intern Med 2010;153:167-175.
-
(2010)
Ann Intern Med
, vol.153
, pp. 167-175
-
-
Unroe, M.1
Kahn, J.M.2
Carson, S.S.3
Govert, J.A.4
Martinu, T.5
Sathy, S.J.6
Clay, A.S.7
Chia, J.8
Gray, A.9
Tulsky, J.A.10
-
6
-
-
77954088532
-
Delirium as a predictor of long-term cognitive impairment in survivors of critical illness
-
Girard TD, Jackson JC, Pandharipande PP, Pun BT, Thompson JL, Shintani AK, Gordon SM, Canonico AE, Dittus RS, Bernard GR, et al. Delirium as a predictor of long-term cognitive impairment in survivors of critical illness. Crit Care Med 2010;38:1513-1520.
-
(2010)
Crit Care Med
, vol.38
, pp. 1513-1520
-
-
Girard, T.D.1
Jackson, J.C.2
Pandharipande, P.P.3
Pun, B.T.4
Thompson, J.L.5
Shintani, A.K.6
Gordon, S.M.7
Canonico, A.E.8
Dittus, R.S.9
Bernard, G.R.10
-
7
-
-
33846296223
-
Incidence, risk factors and consequences of ICU delirium
-
Ouimet S, Kavanagh BP, Gottfried SB, Skrobik Y. Incidence, risk factors and consequences of ICU delirium. Intensive Care Med 2007;33: 66-73.
-
(2007)
Intensive Care Med
, vol.33
, pp. 66-73
-
-
Ouimet, S.1
Kavanagh, B.P.2
Gottfried, S.B.3
Skrobik, Y.4
-
8
-
-
78650818376
-
Factors associated with persistent delirium after intensive care unit admission in an older medical patient population
-
Pisani MA, Murphy TE, Araujo KL, Van Ness PH. Factors associated with persistent delirium after intensive care unit admission in an older medical patient population. J Crit Care 2010;25:540.e1-540.e7.
-
(2010)
J Crit Care
, vol.25
-
-
Pisani, M.A.1
Murphy, T.E.2
Araujo, K.L.3
Van Ness, P.H.4
-
9
-
-
84875790477
-
Factors predisposing to coma and delirium: Fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors
-
Skrobik Y, Leger C, Cossette M, Michaud V, Turgeon J. Factors predisposing to coma and delirium: Fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. Crit Care Med 2013;41:999-1008.
-
(2013)
Crit Care Med
, vol.41
, pp. 999-1008
-
-
Skrobik, Y.1
Leger, C.2
Cossette, M.3
Michaud, V.4
Turgeon, J.5
-
10
-
-
59649126760
-
Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population
-
Pisani MA, Murphy TE, Araujo KL, Slattum P, Van Ness PH, Inouye SK. Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. Crit Care Med 2009;37:177-183.
-
(2009)
Crit Care Med
, vol.37
, pp. 177-183
-
-
Pisani, M.A.1
Murphy, T.E.2
Araujo, K.L.3
Slattum, P.4
Van Ness, P.H.5
Inouye, S.K.6
-
11
-
-
0034891470
-
Delirium in an intensive care unit: A study of risk factors
-
Dubois MJ, Bergeron N, Dumont M, Dial S, Skrobik Y. Delirium in an intensive care unit: A study of risk factors. Intensive Care Med 2001;27:1297-1304.
-
(2001)
Intensive Care Med
, vol.27
, pp. 1297-1304
-
-
Dubois, M.J.1
Bergeron, N.2
Dumont, M.3
Dial, S.4
Skrobik, Y.5
-
12
-
-
33644851831
-
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients
-
Pandharipande P, Shintani A, Peterson J, Pun BT, Wilkinson GR, Dittus RS, Bernard GR, Ely EW. Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology 2006;104:21-26.
-
(2006)
Anesthesiology
, vol.104
, pp. 21-26
-
-
Pandharipande, P.1
Shintani, A.2
Peterson, J.3
Pun, B.T.4
Wilkinson, G.R.5
Dittus, R.S.6
Bernard, G.R.7
Ely, E.W.8
-
13
-
-
84857854451
-
Sedation and analgesia in the mechanically ventilated patient
-
Patel SB, Kress JP. Sedation and analgesia in the mechanically ventilated patient. Am J Respir Crit Care Med 2012;185:486-497.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 486-497
-
-
Patel, S.B.1
Kress, J.P.2
-
14
-
-
84872087535
-
Clinical practice guidelines for the management of pain agitation and delirium in adult patients in the intensive care unit
-
American College of Critical Care Medicine
-
Barr J, Fraser GL, Puntillo K, Ely EW, Gélinas C, Dasta JF, Davidson JE, Devlin JW, Kress JP, Joffe AM, et al.; American College of Critical Care Medicine. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 2013;41:263-306.
-
(2013)
Crit Care Med
, vol.41
, pp. 263-306
-
-
Barr, J.1
Fraser, G.L.2
Puntillo, K.3
Ely, E.W.4
Gélinas, C.5
Dasta, J.F.6
Davidson, J.E.7
Devlin, J.W.8
Kress, J.P.9
Joffe, A.M.10
-
15
-
-
0034682246
-
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation
-
Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000;342:1471-1477.
-
(2000)
N Engl J Med
, vol.342
, pp. 1471-1477
-
-
Kress, J.P.1
Pohlman, A.S.2
O'Connor, M.F.3
Hall, J.B.4
-
16
-
-
38049017332
-
Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): A randomised controlled trial
-
Girard TD, Kress JP, Fuchs BD, Thomason JW, Schweickert WD, Pun BT, Taichman DB, Dunn JG, Pohlman AS, Kinniry PA, et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): A randomised controlled trial. Lancet 2008;371:126-134.
-
(2008)
Lancet
, vol.371
, pp. 126-134
-
-
Girard, T.D.1
Kress, J.P.2
Fuchs, B.D.3
Thomason, J.W.4
Schweickert, W.D.5
Pun, B.T.6
Taichman, D.B.7
Dunn, J.G.8
Pohlman, A.S.9
Kinniry, P.A.10
-
17
-
-
84888203310
-
Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC
-
Haenggi M, Blum S, Brechbuehl R, Brunello A, Jakob SM, Takala J. Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC. Intensive Care Med 2013;39:2171-2179.
-
(2013)
Intensive Care Med
, vol.39
, pp. 2171-2179
-
-
Haenggi, M.1
Blum, S.2
Brechbuehl, R.3
Brunello, A.4
Jakob, S.M.5
Takala, J.6
-
18
-
-
0037111193
-
The Richmond Agitation-Sedation Scale: Validity and reliability in adult intensive care unit patients
-
Sessler CN, Gosnell MS, Grap MJ, Brophy GM, O'Neal PV, Keane KA, Tesoro EP, Elswick RK. The Richmond Agitation-Sedation Scale: Validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med 2002;166:1338-1344.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1338-1344
-
-
Sessler, C.N.1
Gosnell, M.S.2
Grap, M.J.3
Brophy, G.M.4
O'Neal, P.V.5
Keane, K.A.6
Tesoro, E.P.7
Elswick, R.K.8
-
19
-
-
0030012049
-
Sedation of critically ill patients during mechanical ventilation. A comparison of propofol and midazolam
-
Kress JP, O'Connor MF, Pohlman AS, Olson D, Lavoie A, Toledano A, Hall JB. Sedation of critically ill patients during mechanical ventilation. A comparison of propofol and midazolam. Am J Respir Crit Care Med 1996;153:1012-1018.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 1012-1018
-
-
Kress, J.P.1
O'Connor, M.F.2
Pohlman, A.S.3
Olson, D.4
Lavoie, A.5
Toledano, A.6
Hall, J.B.7
-
20
-
-
0035814368
-
Delirium in mechanically ventilated patients: Validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU)
-
Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, Truman B, Speroff T, Gautam S, Margolin R, et al. Delirium in mechanically ventilated patients: Validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA 2001;286:2703-2710.
-
(2001)
JAMA
, vol.286
, pp. 2703-2710
-
-
Ely, E.W.1
Inouye, S.K.2
Bernard, G.R.3
Gordon, S.4
Francis, J.5
May, L.6
Truman, B.7
Speroff, T.8
Gautam, S.9
Margolin, R.10
-
21
-
-
0034948268
-
Evaluation of delirium in critically ill patients: Validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)
-
Ely EW, Margolin R, Francis J, May L, Truman B, Dittus R, Speroff T, Gautam S, Bernard GR, Inouye SK. Evaluation of delirium in critically ill patients: Validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med 2001;29:1370-1379.
-
(2001)
Crit Care Med
, vol.29
, pp. 1370-1379
-
-
Ely, E.W.1
Margolin, R.2
Francis, J.3
May, L.4
Truman, B.5
Dittus, R.6
Speroff, T.7
Gautam, S.8
Bernard, G.R.9
Inouye, S.K.10
-
22
-
-
74949100313
-
Feasibility efficacy and safety of antipsychotics for intensive care unit delirium: The MIND randomized placebo-controlled trial
-
MIND Trial Investigators
-
Girard TD, Pandharipande PP, Carson SS, Schmidt GA, Wright PE, Canonico AE, Pun BT, Thompson JL, Shintani AK, Meltzer HY, et al.; MIND Trial Investigators. Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: The MIND randomized, placebo-controlled trial. Crit Care Med 2010;38:428-437.
-
(2010)
Crit Care Med
, vol.38
, pp. 428-437
-
-
Girard, T.D.1
Pandharipande, P.P.2
Carson, S.S.3
Schmidt, G.A.4
Wright, P.E.5
Canonico, A.E.6
Pun, B.T.7
Thompson, J.L.8
Shintani, A.K.9
Meltzer, H.Y.10
-
23
-
-
78649474311
-
Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: A multicentre, double-blind, placebo-controlled randomised trial
-
van Eijk MM, Roes KC, Honing ML, Kuiper MA, Karakus A, van der Jagt M, Spronk PE, van Gool WA, van der Mast RC, Kesecioglu J, et al. Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: A multicentre, double-blind, placebo-controlled randomised trial. Lancet 2010;376:1829-1837.
-
(2010)
Lancet
, vol.376
, pp. 1829-1837
-
-
Van Eijk, M.M.1
Roes, K.C.2
Honing, M.L.3
Kuiper, M.A.4
Karakus, A.5
Van Der Jagt, M.6
Spronk, P.E.7
Van Gool, W.A.8
Van Der Mast, R.C.9
Kesecioglu, J.10
-
24
-
-
59649127447
-
Dexmedetomidine vs midazolam for sedation of critically ill patients: A randomized trial
-
SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group
-
Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, et al.; SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group. Dexmedetomidine vs midazolam for sedation of critically ill patients: A randomized trial. JAMA 2009;301:489-499.
-
(2009)
JAMA
, vol.301
, pp. 489-499
-
-
Riker, R.R.1
Shehabi, Y.2
Bokesch, P.M.3
Ceraso, D.4
Wisemandle, W.5
Koura, F.6
Whitten, P.7
Margolis, B.D.8
Byrne, D.W.9
Ely, E.W.10
-
25
-
-
80051568597
-
Accurate identification of delirium in the ICU: Problems with translating the evidence in the real-life setting
-
Patel SB, Kress JP. Accurate identification of delirium in the ICU: Problems with translating the evidence in the real-life setting. Am J Respir Crit Care Med 2011;184:287-288.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 287-288
-
-
Patel, S.B.1
Kress, J.P.2
-
26
-
-
84857589102
-
Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: Observational multicentre study
-
van den Boogaard M, Pickkers P, Slooter AJ, Kuiper MA, Spronk PE, van der Voort PH, van der Hoeven JG, Donders R, van Achterberg T, Schoonhoven L. Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: Observational multicentre study. BMJ 2012;344:e420.
-
(2012)
BMJ
, vol.344
-
-
Van Den Boogaard, M.1
Pickkers, P.2
Slooter, A.J.3
Kuiper, M.A.4
Spronk, P.E.5
Van Der Voort, P.H.6
Van Der Hoeven, J.G.7
Donders, R.8
Van Achterberg, T.9
Schoonhoven, L.10
-
27
-
-
37149040245
-
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: The MENDS randomized controlled trial
-
Pandharipande PP, Pun BT, Herr DL, Maze M, Girard TD, Miller RR, Shintani AK, Thompson JL, Jackson JC, Deppen SA, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: The MENDS randomized controlled trial. JAMA 2007;298:2644-2653.
-
(2007)
JAMA
, vol.298
, pp. 2644-2653
-
-
Pandharipande, P.P.1
Pun, B.T.2
Herr, D.L.3
Maze, M.4
Girard, T.D.5
Miller, R.R.6
Shintani, A.K.7
Thompson, J.L.8
Jackson, J.C.9
Deppen, S.A.10
-
28
-
-
0034895041
-
Propofol dosing regimens for ICU sedation based upon an integrated pharmacokinetic-pharmacodynamic model
-
Barr J, Egan TD, Sandoval NF, Zomorodi K, Cohane C, Gambus PL, Shafer SL. Propofol dosing regimens for ICU sedation based upon an integrated pharmacokinetic-pharmacodynamic model. Anesthesiology 2001;95:324-333.
-
(2001)
Anesthesiology
, vol.95
, pp. 324-333
-
-
Barr, J.1
Egan, T.D.2
Sandoval, N.F.3
Zomorodi, K.4
Cohane, C.5
Gambus, P.L.6
Shafer, S.L.7
-
29
-
-
84891026826
-
Sedation level and the prevalence of delirium
-
Brummel NE, Ely EW. Sedation level and the prevalence of delirium. Intensive Care Med 2014;40:135.
-
(2014)
Intensive Care Med
, vol.40
, pp. 135
-
-
Brummel, N.E.1
Ely, E.W.2
-
30
-
-
84891026047
-
Sedation level and prevalence of delirium: Response to Brummel and Ely
-
Haenggi M, Jakob SM, Takala J. Sedation level and prevalence of delirium: Response to Brummel and Ely. Intensive Care Med 2014;40:136.
-
(2014)
Intensive Care Med
, vol.40
, pp. 136
-
-
Haenggi, M.1
Jakob, S.M.2
Takala, J.3
-
31
-
-
78449292957
-
Delayed treatment of delirium increases mortality rate in intensive care unit patients
-
Heymann A, Radtke F, Schiemann A, Lütz A, MacGuill M, Wernecke KD, Spies C. Delayed treatment of delirium increases mortality rate in intensive care unit patients. J Int Med Res 2010;38:1584-1595.
-
(2010)
J Int Med Res
, vol.38
, pp. 1584-1595
-
-
Heymann, A.1
Radtke, F.2
Schiemann, A.3
Lütz, A.4
MacGuill, M.5
Wernecke, K.D.6
Spies, C.7
-
33
-
-
74949114615
-
Efficacy and safety of quetiapine in critically ill patients with delirium: A prospective, multicenter, randomized, double-blind, placebo-controlled pilot study
-
Devlin JW, Roberts RJ, Fong JJ, Skrobik Y, Riker RR, Hill NS, Robbins T, Garpestad E. Efficacy and safety of quetiapine in critically ill patients with delirium: A prospective, multicenter, randomized, double-blind, placebo-controlled pilot study. Crit Care Med 2010;38: 419-427.
-
(2010)
Crit Care Med
, vol.38
, pp. 419-427
-
-
Devlin, J.W.1
Roberts, R.J.2
Fong, J.J.3
Skrobik, Y.4
Riker, R.R.5
Hill, N.S.6
Robbins, T.7
Garpestad, E.8
-
34
-
-
84883447031
-
Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): A randomised, double-blind, placebo-controlled trial
-
Page VJ, Ely EW, Gates S, Zhao XB, Alce T, Shintani A, Jackson J, Perkins GD, McAuley DF. Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): A randomised, double-blind, placebo-controlled trial. Lancet Respir Med 2013;1:515-523.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 515-523
-
-
Page, V.J.1
Ely, E.W.2
Gates, S.3
Zhao, X.B.4
Alce, T.5
Shintani, A.6
Jackson, J.7
Perkins, G.D.8
McAuley, D.F.9
-
35
-
-
65849187703
-
Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised controlled trial
-
Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, Spears L, Miller M, Franczyk M, Deprizio D, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised controlled trial. Lancet 2009;373: 1874-1882.
-
(2009)
Lancet
, vol.373
, pp. 1874-1882
-
-
Schweickert, W.D.1
Pohlman, M.C.2
Pohlman, A.S.3
Nigos, C.4
Pawlik, A.J.5
Esbrook, C.L.6
Spears, L.7
Miller, M.8
Franczyk, M.9
Deprizio, D.10
|