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Volumn 82, Issue 4, 2014, Pages 1698-1709

Type I interferons promote severe disease in a mouse model of lethal ehrlichiosis

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA INTERFERON RECEPTOR; BETA INTERFERON; BETA INTERFERON RECEPTOR; IMMUNOGLOBULIN M;

EID: 84896482877     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01564-13     Document Type: Article
Times cited : (23)

References (68)
  • 1
    • 84867411811 scopus 로고    scopus 로고
    • Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation
    • Piehler J, Thomas C, Garcia KC, Schreiber G. 2012. Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation. Immunol. Rev. 250:317-334. http://dx.doi.org/10.1111/imr.12001.
    • (2012) Immunol. Rev. , vol.250 , pp. 317-334
    • Piehler, J.1    Thomas, C.2    Garcia, K.C.3    Schreiber, G.4
  • 2
    • 84857415635 scopus 로고    scopus 로고
    • Constitutive type I interferon modulates homeostatic balance through tonic signaling
    • Gough DJ, Messina NL, Clarke CJ, Johnstone RW, Levy DE. 2012. Constitutive type I interferon modulates homeostatic balance through tonic signaling. Immunity 36:166-174. http://dx.doi.org/10.1016/j.immuni.2012.01.011.
    • (2012) Immunity , vol.36 , pp. 166-174
    • Gough, D.J.1    Messina, N.L.2    Clarke, C.J.3    Johnstone, R.W.4    Levy, D.E.5
  • 4
    • 0021278452 scopus 로고
    • Endogenous interferon production by endotoxin-responsive macrophages provides an autostimulatory differentiation signal
    • Vogel SN, Fertsch D. 1984. Endogenous interferon production by endotoxin-responsive macrophages provides an autostimulatory differentiation signal. Infect. Immun. 45:417-423.
    • (1984) Infect. Immun. , vol.45 , pp. 417-423
    • Vogel, S.N.1    Fertsch, D.2
  • 6
    • 77957745555 scopus 로고    scopus 로고
    • Type I interferon: friend or foe?
    • Trinchieri G. 2010. Type I interferon: friend or foe? J. Exp. Med. 207: 2053-2063. http://dx.doi.org/10.1084/jem.20101664.
    • (2010) J. Exp. Med. , vol.207 , pp. 2053-2063
    • Trinchieri, G.1
  • 7
    • 84888799401 scopus 로고    scopus 로고
    • Confounding roles for type I interferons during bacterial and viral pathogenesis
    • Carrero JA. 2013. Confounding roles for type I interferons during bacterial and viral pathogenesis. Int. Immunol. 25:663-669. http://dx.doi.org/10.1093/intimm/dxt050.
    • (2013) Int. Immunol. , vol.25 , pp. 663-669
    • Carrero, J.A.1
  • 8
    • 25444495693 scopus 로고    scopus 로고
    • The yin and yang of type I interferon activity in bacterial infection
    • Decker T, Muller M, Stockinger S. 2005. The yin and yang of type I interferon activity in bacterial infection. Nat. Rev. Immunol. 5:675-687. http://dx.doi.org/10.1038/nri1684.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 675-687
    • Decker, T.1    Muller, M.2    Stockinger, S.3
  • 9
    • 77149132187 scopus 로고    scopus 로고
    • Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma
    • Rayamajhi M, Humann J, Penheiter K, Andreasen K, Lenz LL. 2010. Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma. J. Exp. Med. 207:327-337. http://dx.doi.org/10.1084/jem.20091746.
    • (2010) J. Exp. Med. , vol.207 , pp. 327-337
    • Rayamajhi, M.1    Humann, J.2    Penheiter, K.3    Andreasen, K.4    Lenz, L.L.5
  • 10
    • 84856014406 scopus 로고    scopus 로고
    • Type I interferon signaling regulates the composition of inflammatory infiltrates upon infection with Listeria monocytogenes
    • Brzoza-Lewis KL, Hoth JJ, Hiltbold EM. 2012. Type I interferon signaling regulates the composition of inflammatory infiltrates upon infection with Listeria monocytogenes. Cell. Immunol. 273:41-51. http://dx.doi.org/10.1016/j.cellimm.2011.11.008.
    • (2012) Cell. Immunol. , vol.273 , pp. 41-51
    • Brzoza-Lewis, K.L.1    Hoth, J.J.2    Hiltbold, E.M.3
  • 11
    • 84866544929 scopus 로고    scopus 로고
    • Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
    • Robinson N, McComb S, Mulligan R, Dudani R, Krishnan L, Sad S. 2012. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nat. Immunol. 13: 954-962. http://dx.doi.org/10.1038/ni.2397.
    • (2012) Nat. Immunol. , vol.13 , pp. 954-962
    • Robinson, N.1    McComb, S.2    Mulligan, R.3    Dudani, R.4    Krishnan, L.5    Sad, S.6
  • 13
    • 84879602096 scopus 로고    scopus 로고
    • Interferon-beta production via dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C
    • Del Fresno C, Soulat D, Roth S, Blazek K, Udalova I, Sancho D, Ruland J, Ardavin C. 2013. Interferon-beta production via dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans. Immunity 38:1176-1186. http://dx.doi.org/10.1016/j.immuni.2013.05.010.
    • (2013) albicans. Immunity , vol.38 , pp. 1176-1186
    • Del Fresno, C.1    Soulat, D.2    Roth, S.3    Blazek, K.4    Udalova, I.5    Sancho, D.6    Ruland, J.7    Ardavin, C.8
  • 14
    • 0010228473 scopus 로고
    • Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection
    • Buchmeier NA, Schreiber RD. 1985. Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection. Proc. Natl. Acad. Sci. U. S. A. 82:7404-7408. http://dx.doi.org/10.1073/pnas.82.21.7404.
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 7404-7408
    • Buchmeier, N.A.1    Schreiber, R.D.2
  • 15
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • Flynn JL, Chan J, Triebold KJ, Dalton DK, Stewart TA, Bloom BR. 1993. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249-2254. http://dx.doi.org/10.1084/jem.178.6.2249.
    • (1993) J. Exp. Med. , vol.178 , pp. 2249-2254
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 16
    • 79251562853 scopus 로고    scopus 로고
    • Infection-induced myelopoiesis during intracellular bacterial infection is critically dependent upon IFNgamma signaling
    • MacNamara KC, Oduro K, Martin O, Jones DD, McLaughlin M, Choi K, Borjesson DL, Winslow GM. 2011. Infection-induced myelopoiesis during intracellular bacterial infection is critically dependent upon IFNgamma signaling. J. Immunol. 186:1032-1043. http://dx.doi.org/10.4049/jimmunol.1001893.
    • (2011) J. Immunol. , vol.186 , pp. 1032-1043
    • MacNamara, K.C.1    Oduro, K.2    Martin, O.3    Jones, D.D.4    McLaughlin, M.5    Choi, K.6    Borjesson, D.L.7    Winslow, G.M.8
  • 19
    • 29444432905 scopus 로고    scopus 로고
    • Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway
    • Manca C, Tsenova L, Freeman S, Barczak AK, Tovey M, Murray PJ, Barry C, Kaplan G. 2005. Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway. J. Interferon Cytokine Res. 25:694-701. http://dx.doi.org/10.1089/jir.2005.25.694.
    • (2005) J. Interferon Cytokine Res. , vol.25 , pp. 694-701
    • Manca, C.1    Tsenova, L.2    Freeman, S.3    Barczak, A.K.4    Tovey, M.5    Murray, P.J.6    Barry, C.7    Kaplan, G.8
  • 20
    • 0035826721 scopus 로고    scopus 로고
    • Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha/beta
    • Manca C, Tsenova L, Bergtold A, Freeman S, Tovey M, Musser JM, Barry CE, III, Freedman VH, Kaplan G. 2001. Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha/beta. Proc. Natl. Acad. Sci. U. S. A. 98:5752-5757. http://dx.doi.org/10.1073/pnas.091096998.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 5752-5757
    • Manca, C.1    Tsenova, L.2    Bergtold, A.3    Freeman, S.4    Tovey, M.5    Musser, J.M.6    Barry III, C.E.7    Freedman, V.H.8    Kaplan, G.9
  • 21
    • 40949083547 scopus 로고    scopus 로고
    • The importance of early treatment with doxycycline in human ehrlichiosis
    • Hamburg BJ, Storch GA, Micek ST, Kollef MH. 2008. The importance of early treatment with doxycycline in human ehrlichiosis. Medicine 87: 53-60. http://dx.doi.org/10.1097/MD.0b013e318168da1d.
    • (2008) Medicine , vol.87 , pp. 53-60
    • Hamburg, B.J.1    Storch, G.A.2    Micek, S.T.3    Kollef, M.H.4
  • 22
    • 0029036755 scopus 로고
    • Therapeutic delay and mortality in cases of Rocky Mountain spotted fever
    • Kirkland KB, Wilkinson WE, Sexton DJ. 1995. Therapeutic delay and mortality in cases of Rocky Mountain spotted fever. Clin. Infect. Dis. 20:1118-1121. http://dx.doi.org/10.1093/clinids/20.5.1118.
    • (1995) Clin. Infect. Dis. , vol.20 , pp. 1118-1121
    • Kirkland, K.B.1    Wilkinson, W.E.2    Sexton, D.J.3
  • 25
    • 0842326280 scopus 로고    scopus 로고
    • Mechanisms of immunity to Ehrlichia muris: a model of monocytotropic ehrlichiosis
    • Feng HM, Walker DH. 2004. Mechanisms of immunity to Ehrlichia muris: a model of monocytotropic ehrlichiosis. Infect. Immun. 72:966-971. http://dx.doi.org/10.1128/IAI.72.2.966-971.2004.
    • (2004) Infect. Immun. , vol.72 , pp. 966-971
    • Feng, H.M.1    Walker, D.H.2
  • 26
    • 0033998269 scopus 로고    scopus 로고
    • New Ehrlichia species closely related to Ehrlichia chaffeensis isolated from Ixodes ovatus ticks in Japan
    • Shibata S, Kawahara M, Rikihisa Y, Fujita H, Watanabe Y, Suto C, Ito T. 2000. New Ehrlichia species closely related to Ehrlichia chaffeensis isolated from Ixodes ovatus ticks in Japan. J. Clin. Microbiol. 38:1331-1338.
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 1331-1338
    • Shibata, S.1    Kawahara, M.2    Rikihisa, Y.3    Fujita, H.4    Watanabe, Y.5    Suto, C.6    Ito, T.7
  • 27
    • 0035138543 scopus 로고    scopus 로고
    • Animal model of fatal human monocytotropic ehrlichiosis
    • Sotomayor EA, Popov VL, Feng HM, Walker DH, Olano JP. 2001. Animal model of fatal human monocytotropic ehrlichiosis. Am. J. Pathol. 158:757-769. http://dx.doi.org/10.1016/S0002-9440(10)64018-7.
    • (2001) Am. J. Pathol. , vol.158 , pp. 757-769
    • Sotomayor, E.A.1    Popov, V.L.2    Feng, H.M.3    Walker, D.H.4    Olano, J.P.5
  • 28
    • 1642525700 scopus 로고    scopus 로고
    • Overproduction of TNF-alpha by CD8+ type 1 cells and down-regulation of IFN-gamma production by CD4+ Th1 cells con-tribute to toxic shock-like syndrome in an animal model of fatal monocytotropic ehrlichiosis
    • Ismail N, Soong L, McBride JW, Valbuena G, Olano JP, Feng HM, Walker DH. 2004. Overproduction of TNF-alpha by CD8+ type 1 cells and down-regulation of IFN-gamma production by CD4+ Th1 cells con-tribute to toxic shock-like syndrome in an animal model of fatal monocytotropic ehrlichiosis. J. Immunol. 172:1786-1800.
    • (2004) J. Immunol. , vol.172 , pp. 1786-1800
    • Ismail, N.1    Soong, L.2    McBride, J.W.3    Valbuena, G.4    Olano, J.P.5    Feng, H.M.6    Walker, D.H.7
  • 29
    • 33644784688 scopus 로고    scopus 로고
    • Role of tumor necrosis factor alpha (TNF-alpha) and interleukin-10 in the pathogenesis of severe murine monocytotropic ehrlichiosis: increased resistance of TNF receptor p55-and p75-deficient mice to fatal ehrlichial infection
    • Ismail N, Stevenson HL, Walker DH. 2006. Role of tumor necrosis factor alpha (TNF-alpha) and interleukin-10 in the pathogenesis of severe murine monocytotropic ehrlichiosis: increased resistance of TNF receptor p55-and p75-deficient mice to fatal ehrlichial infection. Infect. Immun. 74:1846-1856. http://dx.doi.org/10.1128/IAI.74.3.1846-1856.2006.
    • (2006) Infect. Immun. , vol.74 , pp. 1846-1856
    • Ismail, N.1    Stevenson, H.L.2    Walker, D.H.3
  • 30
    • 33749126557 scopus 로고    scopus 로고
    • Fatal recall responses mediated by CD8 T cells during intracellular bacterial challenge infection
    • Bitsaktsis C, Winslow G. 2006. Fatal recall responses mediated by CD8 T cells during intracellular bacterial challenge infection. J. Immunol. 177: 4644-4651.
    • (2006) J. Immunol. , vol.177 , pp. 4644-4651
    • Bitsaktsis, C.1    Winslow, G.2
  • 33
    • 42949166276 scopus 로고    scopus 로고
    • Protective heterologous immunity against fatal ehrlichiosis and lack of protection following homologous challenge
    • Thirumalapura NR, Stevenson HL, Walker DH, Ismail N. 2008. Protective heterologous immunity against fatal ehrlichiosis and lack of protection following homologous challenge. Infect. Immun. 76:1920-1930. http://dx.doi.org/10.1128/IAI.01293-07.
    • (2008) Infect. Immun. , vol.76 , pp. 1920-1930
    • Thirumalapura, N.R.1    Stevenson, H.L.2    Walker, D.H.3    Ismail, N.4
  • 34
    • 2442645190 scopus 로고    scopus 로고
    • Production of IFN-gamma by CD4 T cells is essential for resolving Ehrlichia infection
    • Bitsaktsis C, Huntington J, Winslow G. 2004. Production of IFN-gamma by CD4 T cells is essential for resolving Ehrlichia infection. J. Immunol. 172:6894-6901.
    • (2004) J. Immunol. , vol.172 , pp. 6894-6901
    • Bitsaktsis, C.1    Huntington, J.2    Winslow, G.3
  • 35
    • 49049088997 scopus 로고    scopus 로고
    • CD11c expression identifies a population of extrafollicular antigen-specific splenic plasmablasts responsible for CD4 T-independent antibody responses during intracellular bacterial infection
    • Racine R, Chatterjee M, Winslow GM. 2008. CD11c expression identifies a population of extrafollicular antigen-specific splenic plasmablasts responsible for CD4 T-independent antibody responses during intracellular bacterial infection. J. Immunol. 181:1375-1385.
    • (2008) J. Immunol. , vol.181 , pp. 1375-1385
    • Racine, R.1    Chatterjee, M.2    Winslow, G.M.3
  • 36
    • 79251540588 scopus 로고    scopus 로고
    • IgM production by bone marrow plasmablasts contributes to long-term protection against intracellular bacterial infection
    • Racine R, McLaughlin M, Jones DD, Wittmer ST, MacNamara KC, Woodland DL, Winslow GM. 2011. IgM production by bone marrow plasmablasts contributes to long-term protection against intracellular bacterial infection. J. Immunol. 186:1011-1021. http://dx.doi.org/10.4049/jimmunol.1002836.
    • (2011) J. Immunol. , vol.186 , pp. 1011-1021
    • Racine, R.1    McLaughlin, M.2    Jones, D.D.3    Wittmer, S.T.4    MacNamara, K.C.5    Woodland, D.L.6    Winslow, G.M.7
  • 37
    • 34548511844 scopus 로고    scopus 로고
    • Relative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis
    • Ismail N, Crossley EC, Stevenson HL, Walker DH. 2007. Relative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis. Infect. Immun. 75:4608-4620. http://dx.doi.org/10.1128/IAI.00198-07.
    • (2007) Infect. Immun. , vol.75 , pp. 4608-4620
    • Ismail, N.1    Crossley, E.C.2    Stevenson, H.L.3    Walker, D.H.4
  • 38
    • 42149129035 scopus 로고    scopus 로고
    • Regulatory roles of CD1d-restricted NKT cells in the induction of toxic shock-like syndrome in an animal model of fatal ehrlichiosis
    • Stevenson HL, Crossley EC, Thirumalapura N, Walker DH, Ismail N. 2008. Regulatory roles of CD1d-restricted NKT cells in the induction of toxic shock-like syndrome in an animal model of fatal ehrlichiosis. Infect. Immun. 76:1434-1444. http://dx.doi.org/10.1128/IAI.01242-07.
    • (2008) Infect. Immun. , vol.76 , pp. 1434-1444
    • Stevenson, H.L.1    Crossley, E.C.2    Thirumalapura, N.3    Walker, D.H.4    Ismail, N.5
  • 39
    • 84877813889 scopus 로고    scopus 로고
    • Neutrophils mediate immunopathology and negatively regulate protective immune responses during fatal bacterial infection-induced toxic shock
    • Yang Q, Ghose P, Ismail N. 2013. Neutrophils mediate immunopathology and negatively regulate protective immune responses during fatal bacterial infection-induced toxic shock. Infect. Immun. 81:1751-1763. http://dx.doi.org/10.1128/IAI.01409-12.
    • (2013) Infect. Immun. , vol.81 , pp. 1751-1763
    • Yang, Q.1    Ghose, P.2    Ismail, N.3
  • 40
    • 69049118144 scopus 로고    scopus 로고
    • Diminished hematopoietic activity associated with alterations in innate and adaptive immunity in a mouse model of human monocytic ehrlichiosis
    • MacNamara KC, Racine R, Chatterjee M, Borjesson D, Winslow GM. 2009. Diminished hematopoietic activity associated with alterations in innate and adaptive immunity in a mouse model of human monocytic ehrlichiosis. Infect. Immun. 77:4061-4069. http://dx.doi.org/10.1128/IAI.01550-08.
    • (2009) Infect. Immun. , vol.77 , pp. 4061-4069
    • MacNamara, K.C.1    Racine, R.2    Chatterjee, M.3    Borjesson, D.4    Winslow, G.M.5
  • 41
    • 18644365244 scopus 로고    scopus 로고
    • Cutting edge: re-evaluating the in vivo cytokine responses of CD8+ T cells during primary and secondary viral infections
    • Liu F, Whitton JL. 2005. Cutting edge: re-evaluating the in vivo cytokine responses of CD8+ T cells during primary and secondary viral infections. J. Immunol. 174:5936-5940.
    • (2005) J. Immunol. , vol.174 , pp. 5936-5940
    • Liu, F.1    Whitton, J.L.2
  • 42
    • 35649027352 scopus 로고    scopus 로고
    • CD4 T-cell epitopes associated with protective immunity induced following vaccination of mice with an ehrlichial variable outer membrane protein
    • Nandi B, Hogle K, Vitko N, Winslow GM. 2007. CD4 T-cell epitopes associated with protective immunity induced following vaccination of mice with an ehrlichial variable outer membrane protein. Infect. Immun. 75:5453-5459. http://dx.doi.org/10.1128/IAI.00713-07.
    • (2007) Infect. Immun. , vol.75 , pp. 5453-5459
    • Nandi, B.1    Hogle, K.2    Vitko, N.3    Winslow, G.M.4
  • 43
    • 84876784453 scopus 로고    scopus 로고
    • MyD88 signaling in CD4 T cells promotes IFN-gamma production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection
    • Zhang Y, Jones M, McCabe A, Winslow GM, Avram D, MacNamara KC. 2013. MyD88 signaling in CD4 T cells promotes IFN-gamma production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection. J. Immunol. 190:4725-4735. http://dx.doi.org/10.4049/jimmunol.1203024.
    • (2013) J. Immunol. , vol.190 , pp. 4725-4735
    • Zhang, Y.1    Jones, M.2    McCabe, A.3    Winslow, G.M.4    Avram, D.5    MacNamara, K.C.6
  • 44
    • 84875114190 scopus 로고    scopus 로고
    • TLR2 and Nod2 mediate resistance or susceptibility to fatal intracellular Ehrlichia infection in murine models of ehrlichiosis
    • Chattoraj P, Yang Q, Khandai A, Al-Hendy O, Ismail N. 2013. TLR2 and Nod2 mediate resistance or susceptibility to fatal intracellular Ehrlichia infection in murine models of ehrlichiosis. PLoS One 8:e58514. http://dx.doi.org/10.1371/journal.pone.0058514.
    • (2013) PLoS One , vol.8
    • Chattoraj, P.1    Yang, Q.2    Khandai, A.3    Al-Hendy, O.4    Ismail, N.5
  • 47
    • 84883704338 scopus 로고    scopus 로고
    • The regulation of immune responses by DC derived type I IFN
    • Ng D, Gommerman JL. 2013. The regulation of immune responses by DC derived type I IFN. Front. Immunol. 4:94. http://dx.doi.org/10.3389/fimmu.2013.00094.
    • (2013) Front. Immunol. , vol.4 , pp. 94
    • Ng, D.1    Gommerman, J.L.2
  • 49
    • 33644755502 scopus 로고    scopus 로고
    • Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors
    • Zhang J, Raper A, Sugita N, Hingorani R, Salio M, Palmowski MJ, Cerundolo V, Crocker PR. 2006. Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors. Blood 107:3600-3608. http://dx.doi.org/10.1182/blood-2005-09-3842.
    • (2006) Blood , vol.107 , pp. 3600-3608
    • Zhang, J.1    Raper, A.2    Sugita, N.3    Hingorani, R.4    Salio, M.5    Palmowski, M.J.6    Cerundolo, V.7    Crocker, P.R.8
  • 50
    • 22144441229 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells-virus experts of innate immunity
    • Barchet W, Cella M, Colonna M. 2005. Plasmacytoid dendritic cells-virus experts of innate immunity. Semin. Immunol. 17:253-261. http://dx.doi.org/10.1016/j.smim.2005.05.008.
    • (2005) Semin. Immunol. , vol.17 , pp. 253-261
    • Barchet, W.1    Cella, M.2    Colonna, M.3
  • 51
    • 58149522035 scopus 로고    scopus 로고
    • Visualization of IFNbeta production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo
    • Scheu S, Dresing P, Locksley RM. 2008. Visualization of IFNbeta production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo. Proc. Natl. Acad. Sci. U. S. A. 105:20416-20421. http://dx.doi.org/10.1073/pnas.0808537105.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 20416-20421
    • Scheu, S.1    Dresing, P.2    Locksley, R.M.3
  • 54
    • 0034232047 scopus 로고    scopus 로고
    • Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox
    • Nguyen KB, Cousens LP, Doughty LA, Pien GC, Durbin JE, Biron CA. 2000. Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox. Nat. Immunol. 1:70-76. http://dx.doi.org/10.1038/76940.
    • (2000) Nat. Immunol. , vol.1 , pp. 70-76
    • Nguyen, K.B.1    Cousens, L.P.2    Doughty, L.A.3    Pien, G.C.4    Durbin, J.E.5    Biron, C.A.6
  • 55
    • 84865619532 scopus 로고    scopus 로고
    • Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells
    • Nakano M, Fujii T, Hashimoto M, Yukawa N, Yoshifuji H, Ohmura K, Nakaizumi A, Mimori T. 2012. Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells. Clin. Exp. Immunol. 170:94-100. http://dx.doi.org/10.1111/j.1365-2249.2012.04638.x.
    • (2012) Clin. Exp. Immunol. , vol.170 , pp. 94-100
    • Nakano, M.1    Fujii, T.2    Hashimoto, M.3    Yukawa, N.4    Yoshifuji, H.5    Ohmura, K.6    Nakaizumi, A.7    Mimori, T.8
  • 56
    • 84863654290 scopus 로고    scopus 로고
    • Rickettsiae induce microvascular hyperpermeability via phosphorylation of VE-cadherins: evidence from atomic force microscopy and biochemical studies
    • Gong B, Ma L, Liu Y, Gong Q, Shelite T, Bouyer D, Boor PJ, Lee YS, Oberhauser A. 2012. Rickettsiae induce microvascular hyperpermeability via phosphorylation of VE-cadherins: evidence from atomic force microscopy and biochemical studies. PLoS Negl. Trop. Dis. 6:e1699. http://dx.doi.org/10.1371/journal.pntd.0001699.
    • (2012) PLoS Negl. Trop. Dis. , vol.6
    • Gong, B.1    Ma, L.2    Liu, Y.3    Gong, Q.4    Shelite, T.5    Bouyer, D.6    Boor, P.J.7    Lee, Y.S.8    Oberhauser, A.9
  • 57
    • 1642433345 scopus 로고    scopus 로고
    • Opposing effect of angiopoietin-1 on VEGF-mediated disruption of endothelial cell-cell interactions requires activation of PKC beta
    • Wang Y, Pampou S, Fujikawa K, Varticovski L. 2004. Opposing effect of angiopoietin-1 on VEGF-mediated disruption of endothelial cell-cell interactions requires activation of PKC beta. J. Cell. Physiol. 198:53-61. http://dx.doi.org/10.1002/jcp.10386.
    • (2004) J. Cell. Physiol. , vol.198 , pp. 53-61
    • Wang, Y.1    Pampou, S.2    Fujikawa, K.3    Varticovski, L.4
  • 62
    • 84876582239 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C: current and future
    • Pawlotsky JM. 2013. Treatment of chronic hepatitis C: current and future. Curr. Top. Microbiol. Immunol. 369:321-342.
    • (2013) Curr. Top. Microbiol. Immunol. , vol.369 , pp. 321-342
    • Pawlotsky, J.M.1
  • 63
    • 84867313947 scopus 로고    scopus 로고
    • IFN-alpha in the treatment of melanoma
    • Tarhini AA, Gogas H, Kirkwood JM. 2012. IFN-alpha in the treatment of melanoma. J. Immunol. 189:3789-3793. http://dx.doi.org/10.4049/jimmunol.1290060.
    • (2012) J. Immunol. , vol.189 , pp. 3789-3793
    • Tarhini, A.A.1    Gogas, H.2    Kirkwood, J.M.3
  • 64
    • 0023178374 scopus 로고
    • Phase I study of recombinant tumor necrosis factor in cancer patients
    • Blick M, Sherwin SA, Rosenblum M, Gutterman J. 1987. Phase I study of recombinant tumor necrosis factor in cancer patients. Cancer Res. 47: 2986-2989.
    • (1987) Cancer Res. , vol.47 , pp. 2986-2989
    • Blick, M.1    Sherwin, S.A.2    Rosenblum, M.3    Gutterman, J.4
  • 65
    • 79951679142 scopus 로고    scopus 로고
    • Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses
    • Barber GN. 2011. Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses. Curr. Opin. Immunol. 23:10-20. http://dx.doi.org/10.1016/j.coi.2010.12.015.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 10-20
    • Barber, G.N.1
  • 68
    • 33847359299 scopus 로고    scopus 로고
    • The type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis
    • Stanley SA, Johndrow JE, Manzanillo P, Cox JS. 2007. The type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J. Immunol. 178: 3143-3152.
    • (2007) J. Immunol. , vol.178 , pp. 3143-3152
    • Stanley, S.A.1    Johndrow, J.E.2    Manzanillo, P.3    Cox, J.S.4


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