Confounding roles for type I interferons during bacterial and viral pathogenesis

International Immunology

Volumn 25, Issue 12, 2013, Pages 663-669

  Carrero, Javier Antonio ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokine; Infection; LCMV; Listeria monocytogenes; Mouse

Indexed keywords

ALPHA INTERFERON RECEPTOR; BETA INTERFERON; CD11B ANTIGEN; CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 5; INTERLEUKIN 10; INTERLEUKIN 17; LISTERIOLYSIN O; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; PALLADIUM; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; VIRUS ANTIBODY;

ADAPTIVE IMMUNITY; APOPTOSIS; ARTICLE; BACTERIAL INFECTION; BONE MARROW CELL; BRUCELLOSIS; CELL DEATH; CYTOKINE PRODUCTION; CYTOSOL; DENDRITIC CELL; GENETIC SUSCEPTIBILITY; HUMAN; INFLAMMATORY INFILTRATE; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; LISTERIOSIS; LYMPHOCYTIC CHORIOMENINGITIS; MACROPHAGE; NATURAL KILLER CELL; NONHUMAN; POPULATION; PRIMARY INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; VIRAL CLEARANCE; VIRUS INFECTION; VIRUS NEUTRALIZATION; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS STRAIN;

CYTOKINE; INFECTION; LCMV; LISTERIA MONOCYTOGENES; MOUSE;

ADAPTIVE IMMUNITY; ANIMALS; BACTERIAL INFECTIONS; DISEASE MODELS, ANIMAL; EXTRACELLULAR SPACE; IMMUNITY, INNATE; INTERFERON TYPE I; INTRACELLULAR SPACE; LISTERIA MONOCYTOGENES; LISTERIOSIS; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, KNOCKOUT; PHENOTYPE; RECEPTOR, INTERFERON ALPHA-BETA; SIGNAL TRANSDUCTION; VIRUS DISEASES;

EID: 84888799401     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxt050     Document Type: Article

References (76)

1. Theofilopoulos, A. N., Baccala, R., Beutler, B. and Kono, D. H. 2005. Type I interferons (alpha/beta) in immunity and autoimmunity. Annu. Rev. Immunol. 23: 307.
2. Stark, G. R. and Darnell, J. E., Jr. 2012. The JAK-STAT pathway at twenty. Immunity 36: 503.
3. Platanias, L. C. 2005. Mechanisms of type-I-and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5: 375.
4. Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H. and Schreiber, R. D. 1998. How cells respond to interferons. Annu. Rev. Biochem. 67: 227.
5. Liu, S. Y., Sanchez, D. J., Aliyari, R., Lu, S. and Cheng, G. 2012. Systematic identification of type I and type II interferon-induced antiviral factors. Proc. Natl Acad. Sci. USA 109: 4239.
6. Müller, U., Steinhoff, U., Reis, L. F. et al. 1994. Functional role of type I and type II interferons in antiviral defense. Science 264: 1918.
7. Trinchieri, G. 2010. Type I interferon: friend or foe? J. Exp. Med. 207: 2053.
8. Smith, P. L., Lombardi, G. and Foster, G. R. 2005. Type I interferons and the innate immune response-more than just antiviral cytokines. Mol. Immunol. 42: 869.
9. Dunn, G. P., Koebel, C. M. and Schreiber, R. D. 2006. Interferons, immunity and cancer immunoediting. Nat. Rev. Immunol. 6: 836.
10. Mordstein, M., Neugebauer, E., Ditt, V. et al. 2010. Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections. J. Virol. 84: 5670.
11. Levy, D. E., Marié, I. J. and Durbin, J. E. 2011. Induction and function of type I and III interferon in response to viral infection. Curr. Opin. Virol. 1: 476.
12. Shresta, S., Kyle, J. L., Snider, H. M., Basavapatna, M., Beatty, P. R. and Harris, E. 2004. Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T-and B-cell-dependent immunity are less critical. J. Virol. 78: 2701.
13. Panchanathan, V., Chaudhri, G. and Karupiah, G. 2005. Interferon function is not required for recovery from a secondary poxvirus infection. Proc. Natl Acad. Sci. USA 102: 12921.
14. Gerlach, N., Schimmer, S., Weiss, S., Kalinke, U. and Dittmer, U. 2006. Effects of type I interferons on Friend retrovirus infection. J. Virol. 80: 3438.
15. Barton, E. S., Lutzke, M. L., Rochford, R. and Virgin, H. W. IV. 2005. Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency. J. Virol. 79: 14149.
16. Price, G. E., Gaszewska-Mastarlarz, A. and Moskophidis, D. 2000. The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice. J. Virol. 74: 3996.
17. García-Sastre, A., Durbin, R. K., Zheng, H. et al. 1998. The role of interferon in influenza virus tissue tropism. J. Virol. 72: 8550.
18. Ou, R., Zhou, S., Huang, L. and Moskophidis, D. 2001. Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells. J. Virol. 75: 8407.
19. Ireland, D. D., Stohlman, S. A., Hinton, D. R., Atkinson, R. and Bergmann, C. C. 2008. Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells. J. Virol. 82: 300.
20. Johansson, C., Wetzel, J. D., He, J., Mikacenic, C., Dermody, T. S. and Kelsall, B. L. 2007. Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus. J. Exp. Med. 204: 1349.
21. Fiette, L., Aubert, C., Müller, U. et al. 1995. Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors. J. Exp. Med. 181: 2069.
22. Samuel, M. A. and Diamond, M. S. 2005. Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival. J. Virol. 79: 13350.
23. Stetson, D. B. and Medzhitov, R. 2006. Type I interferons in host defense. Immunity 25: 373.
24. Garcia-Sastre, A. and Biron, C. A. 2006. Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312: 879.
25. Nguyen, K. B., Salazar-Mather, T. P., Dalod, M. Y. et al. 2002. Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. J. Immunol. 169: 4279.
26. Huber, J. P. and Farrar, J. D. 2011. Regulation of effector and memory T-cell functions by type I interferon. Immunology 132: 466.
27. Sun, S., Zhang, X., Tough, D. F. and Sprent, J. 1998. Type I interferon-mediated stimulation of T cells by CpG DNA. J. Exp. Med. 188: 2335.
28. Deal, E. M., Lahl, K., Narváez, C. F., Butcher, E. C. and Greenberg, H. B. 2013. Plasmacytoid dendritic cells promote rotavirusinduced human and murine B cell responses. J. Clin. Invest. 123: 2464.
29. Jego, G., Palucka, A. K., Blanck, J. P., Chalouni, C., Pascual, V. and Banchereau, J. 2003. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. Immunity 19: 225.
30. Diamond, M. S. 2009. Mechanisms of evasion of the type I interferon antiviral response by flaviviruses. J. Interferon Cytokine Res. 29: 521.
31. Taylor, K. E. and Mossman, K. L. 2013. Recent advances in understanding viral evasion of type I interferon. Immunology 138: 190.
32. Salvato, M., Borrow, P., Shimomaye, E. and Oldstone, M. B. 1991. Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence. J. Virol. 65: 1863.
33. Moskophidis, D., Lechner, F., Pircher, H. and Zinkernagel, R. M. 1993. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 362: 758.
34. Moore, K. W., de Waal Malefyt, R., Coffman, R. L. and O'Garra, A. 2001. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19: 683.
35. Keir, M. E., Butte, M. J., Freeman, G. J. and Sharpe, A. H. 2008. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26: 677.
36. Barber, D. L., Wherry, E. J., Masopust, D. et al. 2006. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682.
37. Teijaro, J. R., Ng, C., Lee, A. M. et al. 2013. Persistent LCMV infection is controlled by blockade of type I interferon signaling. Science 340: 207.
38. Wilson, E. B., Yamada, D. H., Elsaesser, H. et al. 2013. Blockade of chronic type I interferon signaling to control persistent LCMV infection. Science 340: 202.
39. de Almeida, L. A., Carvalho, N. B., Oliveira, F. S. et al. 2011. MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection. PLoS One 6: e23135.
40. Qiu, H., Fan, Y., Joyee, A. G. et al. 2008. Type I IFNs enhance susceptibility to Chlamydia muridarum lung infection by enhancing apoptosis of local macrophages. J. Immunol. 181: 2092.
41. Henry, T., Kirimanjeswara, G. S., Ruby, T. et al. 2010. Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections. J. Immunol. 184: 3755.
42. Carrero, J. A., Calderon, B. and Unanue, E. R. 2004. Type I interferon sensitizes lymphocytes to apoptosis and reduces resistance to Listeria infection. J. Exp. Med. 200: 535.
43. Auerbuch, V., Brockstedt, D. G., Meyer-Morse, N., O'Riordan, M. and Portnoy, D. A. 2004. Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. J. Exp. Med. 200: 527.
44. O'Connell, R. M., Saha, S. K., Vaidya, S. A. et al. 2004. Type I interferon production enhances susceptibility to Listeria monocytogenes infection. J. Exp. Med. 200: 437.
45. Desvignes, L., Wolf, A. J. and Ernst, J. D. 2012. Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis. J. Immunol. 188: 6205.
46. Stanley, S. A., Johndrow, J. E., Manzanillo, P. and Cox, J. S. 2007. The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J. Immunol. 178: 3143.
47. Robinson, N., McComb, S., Mulligan, R., Dudani, R., Krishnan, L. and Sad, S. 2012. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nat. Immunol. 13: 954.
48. Patel, A. A., Lee-Lewis, H., Hughes-Hanks, J., Lewis, C. A. and Anderson, D. M. 2012. Opposing roles for interferon regulatory factor-3 (IRF-3) and type I interferon signaling during plague. PLoS Pathog. 8: e1002817.
49. Mancuso, G., Midiri, A., Biondo, C. et al. 2007. Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria. J. Immunol. 178: 3126.
50. Watanabe, T., Asano, N., Fichtner-Feigl, S. et al. 2010. NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J. Clin. Invest. 120: 1645.
51. Kernbauer, E., Maier, V., Rauch, I., Müller, M. and Decker, T. 2013. Route of infection determines the impact of type I interferons on innate immunity to Listeria monocytogenes. PLoS One 8: e65007.
52. Gratz, N., Hartweger, H., Matt, U. et al. 2011. Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection. PLoS Pathog. 7: e1001345.
53. Antonelli, L. R., Gigliotti Rothfuchs, A., Gonçalves, R. et al. 2010. Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population. J. Clin. Invest. 120: 1674.
54. Tian, X., Xu, F., Lung, W. Y. et al. 2012. Poly I: C enhances susceptibility to secondary pulmonary infections by gram-positive bacteria. PLoS One 7: e41879.
55. Stockinger, S., Materna, T., Stoiber, D. et al. 2002. Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes. J. Immunol. 169: 6522.
56. McCaffrey, R. L., Fawcett, P., O'Riordan, M. et al. 2004. A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc. Natl Acad. Sci. USA 101: 11386.
57. Schnupf, P. and Portnoy, D. A. 2007. Listeriolysin O: a phagosome-specific lysin. Microbes Infect. 9: 1176.
58. Woodward, J. J., Iavarone, A. T. and Portnoy, D. A. 2010. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328: 1703.
59. Bowie, A. G. 2012. Innate sensing of bacterial cyclic dinucleotides: more than just STING. Nat. Immunol. 13: 1137.
60. Parvatiyar, K., Zhang, Z., Teles, R. M. et al. 2012. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat. Immunol. 13: 1155.
61. Stockinger, S., Kastner, R., Kernbauer, E. et al. 2009. Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes. PLoS Pathog. 5: e1000355.
62. Dresing, P., Borkens, S., Kocur, M., Kropp, S. and Scheu, S. 2010. A fluorescence reporter model defines "Tip-DCs" as the cellular source of interferon β in murine listeriosis. PLoS One 5: e15567.
63. Serbina, N. V., Salazar-Mather, T. P., Biron, C. A., Kuziel, W. A. and Pamer, E. G. 2003. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19: 59.
64. Zwaferink, H., Stockinger, S., Hazemi, P., Lemmens-Gruber, R. and Decker, T. 2008. IFN-beta increases listeriolysin O-induced membrane permeabilization and death of macrophages. J. Immunol. 180: 4116.
65. Merrick, J. C., Edelson, B. T., Bhardwaj, V., Swanson, P. E. and Unanue, E. R. 1997. Lymphocyte apoptosis during early phase of Listeria infection in mice. Am. J. Pathol. 151: 785.
66. Zheng, S. J., Jiang, J., Shen, H. and Chen, Y. H. 2004. Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice. J. Immunol. 173: 5652.
67. Carrero, J. A. and Unanue, E. R. 2012. Mechanisms and immunological effects of apoptosis caused by Listeria monocytogenes. Adv. Immunol. 113: 157.
68. Bancroft, G. J., Bosma, M. J., Bosma, G. C. and Unanue, E. R. 1986. Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism. J. Immunol. 137: 4.
69. Carrero, J. A., Calderon, B. and Unanue, E. R. 2006. Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes. J. Exp. Med. 203: 933.
70. Dai, W. J., Köhler, G. and Brombacher, F. 1997. Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice. J. Immunol. 158: 2259.
71. Herbeuval, J. P. and Shearer, G. M. 2007. HIV-1 immunopathogenesis: how good interferon turns bad. Clin. Immunol. 123: 121.
72. Beadling, C. and Slifka, M. K. 2004. How do viral infections predispose patients to bacterial infections? Curr. Opin. Infect. Dis. 17: 185.
73. Li, W., Moltedo, B. and Moran, T. M. 2012. Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of γδ T cells. J. Virol. 86: 12304.
74. Kim, Y. G., Park, J. H., Reimer, T. et al. 2011. Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections. Cell Host Microbe. 9: 496.
75. Barton, E. S., White, D. W., Cathelyn, J. S. et al. 2007. Herpesvirus latency confers symbiotic protection from bacterial infection. Nature 447: 326.
76. Teles, R. M., Graeber, T. G., Krutzik, S. R. et al. 2013. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science 339: 1448.