Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways?

Cellular Signalling

Volumn 26, Issue 6, 2014, Pages 1310-1325

  Daniele, Simona ^a   Trincavelli, Maria Letizia ^a   Fumagalli, Marta ^b   Zappelli, Elisa ^a   Lecca, Davide ^b   Bonfanti, Elisabetta ^b   Campiglia, Pietro ^c   Abbracchio, Maria P ^b   Martini, Claudia ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF SALERNO   (Italy)

Author keywords

GPCR desensitization; GRK arrestin machinery; Intracellular signaling; Oligodendrocyte differentiation; Signaling transduction

Indexed keywords

BETA ARRESTIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 17; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 5; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDOLEUKOTRIENE; PURINE; UNCLASSIFIED DRUG; ADRBK1 PROTEIN, HUMAN; CREB1 PROTEIN, HUMAN; GPR17 PROTEIN, HUMAN; GRK5 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; RETINA S ANTIGEN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; INTRACELLULAR SIGNALING; MOLECULAR INTERACTION; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; ANIMAL; HUMAN; METABOLISM; OLIGODENDROGLIA; PHOSPHORYLATION; PHYSIOLOGY; PRIMARY CELL CULTURE; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; ARRESTINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; G-PROTEIN-COUPLED RECEPTOR KINASE 2; G-PROTEIN-COUPLED RECEPTOR KINASE 5; HUMANS; OLIGODENDROGLIA; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84896443392     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.02.016     Document Type: Article

References (40)

1. Takebayashi H., Nabeshima Y., Yoshida S., Chisaka O., Ikenaka K., Nabeshima Y. Curr. Biol. 2002, 12:1157-1163.
2. Zhou Q., Anderson D.J. Cell 2002, 109:61-73.
3. Lecca D., Trincavelli M.L., Gelosa P., Sironi L., Fumagalli M., Verderio C., Grumelli C., Guerrini U., Tremoli E., Rosa P., Cuboni S., Martini C., Buffo A., Cimino M., Abbracchio M.P. PLoS One 2008, 3:3579-3593.
4. Chen Y., Wu H., Wang S., Koito H., Li J., Ye F., Hoang J., Escobar S.S., Gow A., Arnett H.A., Trapp B.D., Karandikar N.J., Hsieh J., Lu Q.R. Nat. Neurosci. 2009, 12:1398-1406.
5. Fumagalli M., Daniele S., Lecca D., Lee P.R., Parravicini C., Fields R.D., Rosa P., Antonucci F., Verderio C., Trincavelli M.L., Bramanti P., Martini C., Abbracchio M.P. J. Biol. Chem. 2011, 286:10593-10604.
6. Boda E., Viganò F., Rosa P., Fumagalli M., Labat-Gest V., Tempia F., Abbracchio M.P., Dimou L., Buffo A. Glia 2011, 59:1958-1973.
7. Ceruti S., Viganò F., Boda E., Ferrario F., Magni G., Bocazzi M., Rosa P., Buffo A., Abbracchio M.P. Glia 2011, 59:363-378.
8. Fratangeli A., Parmigiani E., Fumagalli M., Lecca D., Benfante R., Passafaro M., Buffo A., Abbracchio M.P., Rosa P. J. Biol. Chem. 2013, 288:5241-5256.
9. Franke H., Parravicini C., Lecca D., Zanier E.R., Heine C., Bremicker K., Fumagalli M., Rosa P., Longhi L., Stocchetti N., De Simoni M.G., Weber M., Abbracchio M.P. Purinergic Signal 2013, 9:451-462.
10. Dougherty J.D., Fomchenko E.L., Akuffo A.A., Schmidt E., Helmy K.Y., Bazzoli E., Brennan C.W., Holland E.C., Milosevic A. Cancer Res. 2012, 72:4856-4868.
11. Ferguson S.S. Pharmacol. Rev. 2001, 53:1-24.
12. Gurevich E.V., Tesmer J.J., Mushegian A., Gurevich V.V. J. Pharmacol. Exp. Ther. 2012, 133:40-69.
13. Mai L., Pei G. J. Cell Sci. 2007, 120:213-218.
14. Ng S.W., Bakowski D., Nelson C., Mehta R., Almeyda R., Bates G., Parekh A.B. Nature 2012, 482:111-115.
15. Giorelli M., Livrea P., Trojano M. J. Neuroimmunol. 2004, 155:143-149.
16. Vroon A., Heijnen C.J., Kavelaars A. J. Leukoc. Biol. 2006, 80:1214-1221.
17. Lombardi M.S., Kavelaars A., Schedlowski M., Bijlsma J.W., Okihara K.L., Van de Pol M., Ochsmann S., Pawlak C., Schmidt R.E., Heijnen C.J. FASEB J. 1999, 13:715-725.
18. Giorelli M., Livrea P., Defazio G., Iacovelli L., Capobianco L., Picascia A., Sellese M., Martino D., Aniello M.S., Trojano M., De Blasi A. Cell. Signal. 2002, 14:673-678.
19. Vroon A., Lombardi M.S., Kavelaars A., Heijnen C.J. J. Neuroimmunol. 2003, 137:79-86.
20. De Blasi A., Parruti G., Sallese M. J. Clin. Invest. 1995, 95:203-210.
21. Vroon A., Kavelaars A., Limmroth V., Lombardi M.S., Goebel M.U., Van Dam A.M., Caron M.G., Schedlowski M., Heijenen C.J. J. Immunol. 2005, 174:4400-4406.
22. Spurney R.F. Calcif. Tissue Int. 2003, 73:153-160.
23. Daniele S., Trincavelli M.L., Gabelloni P., Lecca D., Rosa P., Abbracchio M.P., Martini C. J. Pharmacol. Exp. Ther. 2011, 338:559-567.
24. Carotenuto A., Cipolletta E., Gomez-Monterrey I., Sala M., Vernieri E., Limatola A., Bertamino A., Musella S., Sorriento D., Grieco P., Trimarco B., Novellino E., Iaccarino G., Campiglia P. Eur. J. Med. Chem. 2013, 69:384-392.
25. Chuang T.T., Paolucci L., De Blasi A. J. Biol. Chem. 1996, 271:28691-28696.
26. Daniele S., Lecca D., Trincavelli M.L., Ciampi O., Abbracchio M.P., Martini C. Cell. Signal. 2010, 22:697-706.
27. Martini C., Da Pozzo E., Carmassi C., Cuboni S., Trincavelli M.L., Massimetti G., Marazziti D., Dell'Osso L. World J. Biol. Psychiatry 2013, 14:396-402.
28. Coppi E., Cellai L., Maraula G., Pugliese A.M., Pedata F. Neuropharmacol. 2013, 73:301-310.
29. Communi D., Gonzales N.S., Detheux M., Brèzillon S., Lannoy V., Parmentier M., Boeynaems J.M. J. Biol. Chem. 2001, 276:41479-41485.
30. Luttrell L.M., Gesty-Palmer D. Pharmacol. Rev. 2010, 62:305-330.
31. Yang S.H., Sharrocks A.D., Whitmarsh A.J. Gene 2013, 513:1-13.
32. DeWire S.M., Ahn S., Lefkowitz R.J., Shenoy S.K. Annu. Rev. Physiol. 2007, 69:483-510.
33. Zheng H., Loh H.H., Law P.Y. Mol. Pharmacol. 2008, 73:178-190.
34. Hennen S., Wang H., Peters L., Merten N., Simon K., Spinrath A., Blättermann S., Akkari R., Schrage R., Schröder R., Schulz D., Vermeiren C., Zimmermann K., Kehraus S., Drewke C., Pfeifer A., König G.M., Mohr K., Gillard M., Müller C.E., Lu Q.R., Gomeza J., Kostenis E. Sci. Signal. 2013, 22:ra93.
35. Ishii A., Furusho M., Bansal R. J. Neurosci. 2013, 33:175-186.
36. Urban J.D., Clarke W.P., von Zastrow M., Nichols D.E., Kobilka B., Weinstein H., Javitch J.A., Roth B.L., Christopoulos A., Sexton P.M. J. Pharmacol. Exp. Ther. 2007, 320:1-13.
37. Kim J., Clarke W.P., von Zastrow M., Nichols D.E., Kobilka B., Weinstein H., Javitch J.A., Roth B.L., Christopoulos A., Sexton P.M., Miller K.J., Spedding M., Mailman R.B. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:1442-1447.
38. Ren X.R., Reiter E., Ahn S., Kim J., Chen W., Lefkowitz R.J. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:1448-1453.
39. Shenoy S.K., Drake M.T., Nelson C.D., Houtz D.A., Xiao K., Madabushi S., Reiter E., Premont R.T., Lichtarge O., Lefkowitz R.J. J. Biol. Chem. 2005, 281:1261-1273.
40. Sato-Bigbee C., Pal S., Chu A.K. J. Neurochem. 1999, 72:139-147.