Coincidental metabolic syndrome increases the risk of liver fibrosis progression in patients with chronic hepatitis B - A prospective cohort study with paired transient elastography examinations

Alimentary Pharmacology and Therapeutics

Volumn 39, Issue 8, 2014, Pages 883-893

  Wong, G L H ^a,b   Chan, H L Y ^a,b   Yu, Z ^b   Chan, A W H ^a   Choi, P C L ^a   Chim, A M L ^a,b   Chan, H Y ^a,b   Tse, C H ^a,b   Wong, V W S ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HIGH DENSITY LIPOPROTEIN; VIRUS DNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; COHORT ANALYSIS; DISEASE ASSOCIATION; ELASTOGRAPHY; FEMALE; HEPATITIS B; HUMAN; HUMAN TISSUE; LIVER BIOPSY; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; OBESITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; VIRUS LOAD;

ADULT; ALANINE TRANSAMINASE; COHORT STUDIES; DISEASE PROGRESSION; ELASTICITY IMAGING TECHNIQUES; FEMALE; FOLLOW-UP STUDIES; HEPATITIS B, CHRONIC; HUMANS; LIVER CIRRHOSIS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; OBESITY, ABDOMINAL; PROSPECTIVE STUDIES; RISK FACTORS; VIRAL LOAD;

EID: 84896400692     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/apt.12658     Document Type: Article

References (48)

1. Chan HL, Sung JJ,. Hepatocellular carcinoma and hepatitis B virus. Semin Liver Dis 2006; 26: 153-61.
2. Chan HL, Tse CH, Mo F, et al,. High viral load and hepatitis B virus subgenotype ce are associated with increased risk of hepatocellular carcinoma. J Clin Oncol 2008; 26: 177-82.
3. Lai CL, Ratziu V, Yuen MF, Poynard T,. Viral hepatitis B. Lancet 2003; 362: 2089-94.
4. Wong GL, Chan HL, Chan HY, et al,. Accuracy of risk scores for patients with chronic hepatitis B receiving entecavir treatment. Gastroenterology 2013; 144: 933-44.
5. Wong VW, Chan SL, Mo F, et al,. Clinical scoring system to predict hepatocellular carcinoma in chronic hepatitis B carriers. J Clin Oncol 2010; 28: 1660-5.
6. Wong GL, Wong VW, Choi PC, et al,. Metabolic syndrome increases the risk of liver cirrhosis in chronic hepatitis B. Gut 2009; 58: 111-7.
7. Chitturi S, Wong VW, Farrell G,. Nonalcoholic fatty liver in Asia: firmly entrenched and rapidly gaining ground. J Gastroenterol Hepatol 2011; 26 (Suppl. 1): 163-72.
8. Wong VW, Wong GL, Yu J, et al,. Interaction of adipokines and hepatitis B virus on histological liver injury in the Chinese. Am J Gastroenterol 2010; 105: 132-8.
9. Wong GL,. Transient elastography: kill two birds with one stone World J Hepatol 2013; 5: 264-74.
10. Chan HL, Wong GL, Choi PC, et al,. Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B. J Viral Hepat 2009; 16: 36-44.
11. Wong GL, Wong VW, Choi PC, Chan AW, Chan HL,. Development of a non-invasive algorithm with transient elastography (Fibroscan) and serum test formula for advanced liver fibrosis in chronic hepatitis B. Aliment Pharmacol Ther 2010; 31: 1095-103.
12. Wong VW, Vergniol J, Wong GL, et al,. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology 2010; 51: 454-62.
13. Wong GL, Wong VW, Choi PC, et al,. Evaluation of alanine transaminase and hepatitis B virus DNA to predict liver cirrhosis in hepatitis B e antigen-negative chronic hepatitis B using transient elastography. Am J Gastroenterol 2008; 103: 3071-81.
14. Wong GL, Wong VW, Choi PC, et al,. Clinical factors associated with liver stiffness in hepatitis B e antigen-positive chronic hepatitis B patients. Clin Gastroenterol Hepatol 2009; 7: 227-33.
15. Wong GL, Chan HL, Yu Z, Chan HY, Tse CH, Wong VW,. Liver fibrosis progression is uncommon in patients with inactive chronic hepatitis B-a prospective cohort study with paired transient elastography examination. J Gastroenterol Hepatol 2013; 28: 1842-8.
16. Wong GL, Chan HL, Yu Z, Chan HY, Tse CH, Wong VW,. Liver fibrosis progression in chronic hepatitis B patients positive for hepatitis B e antigen: a prospective cohort study with paired transient elastography examination. J Gastroenterol Hepatol 2013; 28: 1762-9.
17. WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004; 363: 157-63.
18. Chan HL, Chui AK, Lau WY, et al,. Factors associated with viral breakthrough in lamivudine monoprophylaxis of hepatitis B virus recurrence after liver transplantation. J Med Virol 2002; 68: 182-7.
19. Chan HL, Thompson A, Martinot-Peignoux M, et al,. Hepatitis B surface antigen quantification: Why and how to use it in 2011-a core group report. J Hepatol 2011; 55: 1121-31.
20. Grundy SM, Cleeman JI, Daniels SR, et al,. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 2735-52.
21. Wong GL, Wong VW, Choi PC, et al,. Assessment of fibrosis by transient elastography compared with liver biopsy and morphometry in chronic liver diseases. Clin Gastroenterol Hepatol 2008; 6: 1027-35.
22. Wong VW, Wong GL, Chan FK,. Liver stiffness measurement: simplicity is prerequisite for reliability. Gastroenterology 2013; 144: 243-4.
23. Wong GL, Wong VW, Choi PC, et al,. On-treatment monitoring of liver fibrosis with transient elastography in chronic hepatitis B patients. Antivir Ther 2011; 16: 165-72.
24. European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of chronic hepatitis B virus infection. J Hepatol 2012; 57: 167-85.
25. Liaw YF, Kao JH, Piratvisuth T, et al,. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update. Hepatol Int 2012; 6: 531-61.
26. Lok AS, McMahon BJ,. Chronic hepatitis B: update 2009. Hepatology 2009; 50: 661-2.
27. Ishak K, Baptista A, Bianchi L, et al,. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22: 696-9.
28. Yoon H, Lee JG, Yoo JH, et al,. Effects of metabolic syndrome on fibrosis in chronic viral hepatitis. Gut Liver 2013; 7: 469-74.
29. Wong VW, Chu WC, Wong GL, et al,. Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: a population study using proton-magnetic resonance spectroscopy and transient elastography. Gut 2012; 61: 409-15.
30. Wong VW, Wong GL, Chu WC, et al,. Hepatitis B virus infection and fatty liver in the general population. J Hepatol 2012; 56: 533-40.
31. Rubbia-Brandt L, Fabris P, Paganin S, et al,. Steatosis affects chronic hepatitis C progression in a genotype specific way. Gut 2004; 53: 406-12.
32. Cheng YL, Wang YJ, Kao WY, et al,. Inverse association between hepatitis B virus infection and fatty liver disease: a large-scale study in populations seeking for check-up. PLoS ONE 2013; 8: e72049.
33. Minakari M, Molaei M, Shalmani HM, et al,. Liver steatosis in patients with chronic hepatitis B infection: host and viral risk factors. Eur J Gastroenterol Hepatol 2009; 21: 512-6.
34. Sebastiani G, Tempesta D, Alberti A,. Hepatic iron overload is common in chronic hepatitis B and is more severe in patients coinfected with hepatitis D virus. J Viral Hepat 2012; 19: e170-6.
35. Thomopoulos KC, Arvaniti V, Tsamantas AC, et al,. Prevalence of liver steatosis in patients with chronic hepatitis B: a study of associated factors and of relationship with fibrosis. Eur J Gastroenterol Hepatol 2006; 18: 233-7.
36. Paradis V, Perlemuter G, Bonvoust F, et al,. High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis. Hepatology 2001; 34 (4 Pt 1): 738-44.
37. Chao LT, Wu CF, Sung FY, et al,. Insulin, glucose and hepatocellular carcinoma risk in male hepatitis B carriers: results from 17-year follow-up of a population-based cohort. Carcinogenesis 2011; 32: 876-81.
38. Zhao J, Zhao Y, Wang H, Gu X, Ji J, Gao C,. Association between metabolic abnormalities and HBV related hepatocelluar carcinoma in Chinese: a cross-sectional study. Nutr J 2011; 10: 49.
39. Marcellin P, Gane E, Buti M, et al,. Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study. Lancet 2013; 381: 468-75.
40. Ko GT, Tang JS,. Metabolic syndrome in the Hong Kong community: the United Christian Nethersole Community Health Service primary healthcare programme 2001-2002. Singapore Med J 2007; 48: 1111-6.
41. Nestel P, Lyu R, Low LP, et al,. Metabolic syndrome: recent prevalence in East and Southeast Asian populations. Asia Pac J Clin Nutr 2007; 16: 362-7.
42. Surgeon General's report on physical activity and health. From the Centers for Disease Control and Prevention. JAMA 1996; 276: 522.
43. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000; 894: i-xii, 1-253.
44. Summers LK, Fielding BA, Bradshaw HA, et al,. Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity. Diabetologia 2002; 45: 369-77.
45. Vessby B, Uusitupa M, Hermansen K, et al,. Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: the KANWU Study. Diabetologia 2001; 44: 312-9.
46. Wong VW, Chan RS, Wong GL, et al,. Community-based lifestyle modification programme for non-alcoholic fatty liver disease: a randomized controlled trial. J Hepatol 2013; 59: 536-42.
47. Wong GL, Wong VW, Chim AM, et al,. Factors associated with unreliable liver stiffness measurement and its failure with transient elastography in the Chinese population. J Gastroenterol Hepatol 2011; 26: 300-5.
48. Wong GL, Chan HL, Choi PC, et al,. Association between anthropometric parameters and measurements of liver stiffness by transient elastography. Clin Gastroenterol Hepatol 2013; 11: 295-302.e1-3.