Design, synthesis and in vitro evaluation of 18β-glycyrrhetinic acid derivatives for anticancer activity against human breast cancer cell line MCF-7

Current Medicinal Chemistry

Volumn 21, Issue 9, 2014, Pages 1160-1170

  Yadav, Dharmendra Kumar ^a   Kalani, Komal ^a   Singh, Abhishek K ^b   Khan, Feroz ^a   Srivastava, Santosh K ^a   Pant, Aditya B ^b  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

18 glycyrrhetinic acid; ADMET; Cell line MCF 7; Human breast cancer; QSAR

Indexed keywords

ANTINEOPLASTIC AGENT; BENZYL AMIDE; ETHYL OXALYL; GLYCYRRHETINIC ACID DERIVATIVE; OCTYLAMIDE; PACLITAXEL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BIOASSAY; BREAST CANCER; CANCER CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN MCF 7; CYTOTOXICITY; DIPOLE; DRUG DESIGN; DRUG SYNTHESIS; ENERGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL SURVIVAL; DRUG DESIGN; GLYCYRRHETINIC ACID; HUMANS; MCF-7 CELLS; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84896387635     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/09298673113206660330     Document Type: Article

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