Synthesis and in vitro cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6- diazacyclopenta[b]anthracene-5,10-diones

Archives of Pharmacal Research

Volumn 33, Issue 5, 2010, Pages 663-667

  Kwak, Jae Hwan ^a   Namgoong, Kwon ^a   Jung, Jae Kyung ^a   Han, Sang Bae ^a   Cho, Jungsook ^b   Kim, Hwan Mook ^c   Park, Song Gyu ^c   Lee, Kiho ^c   Kang, Jong Soon ^c   Lee, Heesoon ^a  

^a Chungbuk National University   (South Korea)

^b Dongguk University College of Medicine   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Cytotoxic activity; Diazacyclopenta b anthracene 5,10 diones

Indexed keywords

2 (2 DIETHYLAMINOETHYL) 2,3 DIHYDRO 1H 2,6 DIAZACYCLOPENTA[B] ANTHRACENE 5,10 DIONE; 2 BUTYL 2,3 DIHYDRO 1H 2,6 DIAZACYCLOPENTA[B] ANTHRACENE 5,10 DIONE; 2 CYCLOBUTYL 2,3 DIHYDRO 1H 2,6 DIAZACYCLOPENTA[B] ANTHRACENE 5,10 DIONE; 2 CYCLOHEXYL 2,3 DIHYDRO 1H 2,6 DIAZACYCLOPENTA[B] ANTHRACENE 5,10 DIONE; 2 CYCLOPENTYL 2,3 DIHYDRO 1H 2,6 DIAZACYCLOPENTA[B]ANTHRACENE 5,10 DIONE; 2 CYCLOPROPYL 2,3 DIHYDRO 1H 2,6 DIAZACYCLOPENTA[B] ANTHRACENE 5,10 DIONE; ANTHRACENE DERIVATIVE; DOXORUBICIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG RESISTANCE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANTHRACENES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77954532381     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-0503-z     Document Type: Article

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