Metronidazole or cotrimoxazole therapy is associated with a decrease in intestinal bioavailability of common antiretroviral drugs

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Dossou Yovo, Flore ^a   Mamadou, Godefroy ^b   Soudy, Imar Djibrine ^b,c   Limas Nzouzi, Nicolas ^b   Miantezila, Joe ^b   Desjeux, Jehan François ^d   Eto, Bruno ^b  

^a University of Paris Cité   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Institut Universitaire des Sciences et Technique d'Abéché   (Chad)

^d ACADÉMIE NATIONALE DE MÉDECINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATAZANAVIR; COTRIMOXAZOLE; METRONIDAZOLE; RITONAVIR; ANTIRETROVIRUS AGENT; OLIGOPEPTIDE; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASCENDING COLON; COLON MUCOSA; CONTROLLED STUDY; DESCENDING COLON; DRUG BIOAVAILABILITY; ELECTRIC CONDUCTIVITY; MALE; NONHUMAN; RAT; THICKNESS; TRANSEPITHELIAL ELECTRICAL CONDUCTANCE; ANALYSIS OF VARIANCE; ANIMAL; BIOAVAILABILITY; COLON; DRUG EFFECTS; HIV INFECTIONS; INTESTINE ABSORPTION; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ANIMALS; ANTI-RETROVIRAL AGENTS; ATAZANAVIR SULFATE; BIOLOGICAL AVAILABILITY; COLON; ELECTRIC CONDUCTIVITY; HIV INFECTIONS; INTESTINAL ABSORPTION; MALE; METRONIDAZOLE; OLIGOPEPTIDES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RITONAVIR; TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION;

EID: 84896349630     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089943     Document Type: Article

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