Degradation kinetics of metronidazole and olsalazine by bacteria in ascending colon and in feces of healthy adults

International Journal of Pharmaceutics

Volumn 413, Issue 1-2, 2011, Pages 81-86

  Vertzoni, Maria ^a   Carlsson, Anders ^b   Abrahamsson, Bertil ^b   Goumas, Konstantinos ^c   Reppas, Christos ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b ASTRAZENECA R AND D   (Sweden)

^c RED CROSS HOSPITAL   (Greece)

Author keywords

Ascending colon; Degradation kinetics; Feces; Metronidazole; Olsalazine

Indexed keywords

METRONIDAZOLE; OLSALAZINE; SODIUM CHLORIDE;

ADULT; ANAEROBIC DIGESTION; ARTICLE; ASCENDING COLON; CONTROLLED STUDY; DEGRADATION KINETICS; DIET RESTRICTION; DRUG BIOAVAILABILITY; EX VIVO STUDY; FECES ANALYSIS; HUMAN; HUMAN EXPERIMENT; MATERIAL STATE; NORMAL HUMAN; PRECIPITATION; PRIORITY JOURNAL; ULTRACENTRIFUGATION;

ADULT; AMINOSALICYLIC ACIDS; ANTI-INFECTIVE AGENTS; BACTERIA; COLON, ASCENDING; FECES; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; MALE; METRONIDAZOLE; MIDDLE AGED; YOUNG ADULT;

EID: 79958000416     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.028     Document Type: Article

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