Evaluating state dependence and subtype selectivity of calcium channel modulators in automated electrophysiology assays

Assay and Drug Development Technologies

Volumn 12, Issue 2, 2014, Pages 110-119

  Kuryshev, Yuri A ^a   Brown, Arthur M ^a   Duzic, Emir ^a   Kirsch, Glenn E ^a  

^a ChanTest Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; MIBEFRADIL; NIFEDIPINE; PIMOZIDE; RECEPTOR SUBTYPE; VERAPAMIL; VOLTAGE GATED CALCIUM CHANNEL; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT;

ARTICLE; AUTOMATION; CALCIUM TRANSPORT; ELECTROPHYSIOLOGY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; PATCH CLAMP TECHNIQUE; RECEPTOR SENSITIVITY; VALIDATION PROCESS; ANIMAL; CHO CELL LINE; CRICETULUS; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HAMSTER; HEK293 CELL LINE; MEMBRANE POTENTIAL; PHYSIOLOGY; PROCEDURES;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION; ELECTROPHYSIOLOGICAL PHENOMENA; HEK293 CELLS; HUMANS; MEMBRANE POTENTIALS;

EID: 84896347624     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2013.552     Document Type: Article

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