An ion channel library for drug discovery and safety screening on automated platforms

Assay and Drug Development Technologies

Volumn 6, Issue 6, 2008, Pages 765-780

  Wible, Barbara A ^a   Kuryshev, Yuri A ^a   Smith, Stephen S ^a   Liu, Zhiqi ^a   Brown, Arthur M ^a  

^a ChanTest Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SENSING ION CHANNEL; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHLORIDE CHANNEL; COMPLEMENTARY DNA; CYCLIC NUCLEOTIDE GATED CHANNEL; ION CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL CELL CULTURE; AUTOMATION; CELL STRAIN HEK293; CHO CELL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; ELECTROPHYSIOLOGY; FEMALE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MEDICAL TECHNOLOGY; MOLECULAR CLONING; NONHUMAN; PROTEIN EXPRESSION; REVIEW; RISK ASSESSMENT;

ANIMALS; ASTEMIZOLE; AUTOMATION; CELL LINE; CHO CELLS; CLONING, ORGANISM; CRICETINAE; CRICETULUS; DNA, COMPLEMENTARY; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; DRUG TOXICITY; FLUORESCENT DYES; HUMANS; INHIBITORY CONCENTRATION 50; ION CHANNELS; PIMOZIDE; TERFENADINE;

EID: 58849153580     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2008.171     Document Type: Review

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