microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris

British Journal of Dermatology

Volumn 165, Issue 5, 2011, Pages 1003-1010

  Ichihara, A ^a   Jinnin, M ^a   Yamane, K ^a   Fujisawa, A ^a   Sakai, K ^a   Masuguchi, S ^a   Fukushima, S ^a   Maruo, K ^a   Ihn, H ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; SMALL INTERFERING RNA; CCNE1 PROTEIN, HUMAN; MIRN424 MICRORNA, HUMAN; ONCOPROTEIN;

ADULT; AGED; ARTICLE; ATOPIC DERMATITIS; CELL COUNT; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; IN VIVO CULTURE; KERATINOCYTE; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PSORIASIS VULGARIS; UPREGULATION; CASE CONTROL STUDY; CELL CULTURE; METABOLISM; MIDDLE AGED; PATHOLOGY; PSORIASIS;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN E; FEMALE; HUMANS; KERATINOCYTES; MALE; MAP KINASE KINASE 1; MICRORNAS; MIDDLE AGED; ONCOGENE PROTEINS; PSORIASIS;

EID: 84856401413     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2011.10497.x     Document Type: Article

References (30)

1. Roberson E, Bowcock A. Psoriasis genetics: breaking the barrier. Trends Genet 2010; 26:415-23.
2. Henseler T, Christophers E. Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol 1985; 13:450-6. (Pubitemid 15016489)
3. Stuart P, Malick F, Nair R et al. Analysis of phenotypic variation in psoriasis as a function of age at onset and family history. Arch Dermatol Res 2002; 294:207-13. (Pubitemid 34762295)
4. Sand M, Gambichler T, Sand D et al. MicroRNAs and the skin: tiny players in the body's largest organ. J Dermatol Sci 2009; 53:169-75.
5. Friedman R, Farh K, Burge C et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009; 19:92-105.
6. Bostjancic E, Glavac D. Importance of microRNAs in skin morphogenesis and diseases. Acta Dermatovenerol Alp Panonica Adriat 2008; 17:95-102.
7. Herrera B, Lockstone H, Taylor J et al. Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia 2010; 53:1099-109.
8. Chen Y, Gorski D. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 2008; 111:1217-26. (Pubitemid 351213403)
9. Davidson-Moncada J, Papavasiliou F, Tam W. MicroRNAs of the immune system: roles in inflammation and cancer. Ann N Y Acad Sci 2010; 1183:183-94.
10. Kuehbacher A, Urbich C, Dimmeler S. Targeting microRNA expression to regulate angiogenesis. Trends Pharmacol Sci 2008; 29:12-15.
11. Furer V, Greenberg J, Attur M et al. The role of microRNA in rheumatoid arthritis and other autoimmune diseases. Clin Immunol 2010; 136:1-15.
12. Kroh EM, Parkin RK, Mitchell PS et al. Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR). Methods 2010; 50:298-301.
13. Mitchell PS, Parkin RK, Kroh EM et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA 2008; 105:10513-18.
14. Gilad S, Meiri E, Yogev Y et al. Serum microRNAs are promising novel biomarkers. PLoS ONE 2008; 3:e3148.
15. Zhu W, Qin W, Atasoy U et al. Circulating microRNAs in breast cancer and healthy subjects. BMC Res Notes 2009; 2:89.
16. Jinnin M, Ihn H, Asano Y et al. Platelet derived growth factor induced tenascin-C transcription is phosphoinositide 3-kinase/Akt-dependent and mediated by Ets family transcription factors. J Cell Physiol 2006; 206:718-27. (Pubitemid 43191047)
17. Makino T, Jinnin M, Muchemwa F et al. Basic fibroblast growth factor stimulates the proliferation of human dermal fibroblasts via the ERK1/2 and JNK pathways. Br J Dermatol 2010; 162:717-23.
18. Lewis B, Burge C, Bartel D. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120:15-20. (Pubitemid 40094598)
19. Greulich H, Erikson R. An analysis of Mek1 signaling in cell proliferation and transformation. J Biol Chem 1998; 273:13280-8. (Pubitemid 28246901)
20. Möröy T, Geisen C. Cyclin E. Int J Biochem Cell Biol 2004; 36:1424-39.
21. Carthew R, Sontheimer E. Origins and mechanisms of miRNAs and siRNAs. Cell 2009; 136:642-55.
22. Sonkoly E, Wei T, Janson P et al. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS ONE 2007; 2:e610.
23. Sonkoly E, Ståhle M, Pivarcsi A. MicroRNAs: novel regulators in skin inflammation. Clin Exp Dermatol 2008; 33:312-15. (Pubitemid 351550660)
24. Zibert J, Løvendorf M, Litman T et al. MicroRNAs and potential target interactions in psoriasis. J Dermatol Sci 2010; 58:177-85.
25. Scholl FA, Dumesic PA, Khavari PA. Mek1 alters epidermal growth and differentiation. Cancer Res 2004; 64:6035-40. (Pubitemid 39129401)
26. Haase I, Hobbs R, Romero M et al. A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis. J Clin Invest 2001; 108:527-36. (Pubitemid 32777732)
27. Hwang H, Clurman B. Cyclin E in normal and neoplastic cell cycles. Oncogene 2005; 24:2776-86. (Pubitemid 40638089)
28. Caldon C, Musgrove E. Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer. Cell Div 2010; 5:2.
29. Ramos J. The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells. Int J Biochem Cell Biol 2008; 40:2707-19.
30. Keenan S, Bellone C, Baldassare J. Cyclin-dependent kinase 2 nucle-ocytoplasmic translocation is regulated by extracellular regulated kinase. J Biol Chem 2001; 276:22404-9.