Expression of chimeric receptor CD4ζ by natural killer cells derived from human pluripotent stem cells improves in vitro activity but does not enhance suppression of HIV infection in vivo

Stem Cells

Volumn 32, Issue 4, 2014, Pages 1021-1031

  Ni, Zhenya ^a   Knorr, David A ^a   Bendzick, Laura ^a   Allred, Jeremy ^a   Kaufman, Dan S ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

HIV 1 infection inhibition; Human embryonic stem cells; In vitro; In vivo; Induced pluripotent stem cells; Natural killer cells

Indexed keywords

ANTIGEN; CD3ZETA ANTIGEN; CD4ZETA ANTIGEN; UNCLASSIFIED DRUG; CD4 ANTIGEN; HYBRID PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; EMBRYONIC STEM CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PLURIPOTENT STEM CELL; VIRUS LOAD; VIRUS REPLICATION; ANIMAL; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PATHOLOGY; STEM CELL TRANSPLANTATION;

ANIMALS; ANTIGENS, CD4; CELL LINE; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HIV INFECTIONS; HIV-1; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KILLER CELLS, NATURAL; MICE; RECOMBINANT FUSION PROTEINS; STEM CELL TRANSPLANTATION;

EID: 84896324199     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1611     Document Type: Article

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