Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5′-exonuclease activity

Journal of Biological Chemistry

Volumn 289, Issue 11, 2014, Pages 7825-7834

  Li, Sicong ^a   Chang, Howard H ^a   Niewolik, Doris ^b   Hedrick, Michael P ^c   Pinkerton, Anthony B ^c   Hassig, Christian A ^c   Schwarz, Klaus ^b   Lieber, Michael R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b German Red Cross Blood Transfusion Service Baden Württemberg Hessen and University Hospital Ulm   (Germany)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

ACTIVE SITE RESIDUES; DIVALENT CATION; ENDONUCLEASE ACTIVITIES; ENDONUCLEASES; EXONUCLEASE ACTIVITY; PROTEIN FAMILY; SINGLE-STRANDED DNA; SMALL MOLECULE INHIBITOR;

DNA;

ARTEMIS; DEOXYRIBONUCLEASE; METALLO BETA LACTAMASE; PHOSPHODIESTERASE I; UNCLASSIFIED DRUG;

ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SPECIFICITY; HOST CELL; POINT MUTATION; PRIORITY JOURNAL;

DNA REPAIR; NONHOMOLOGOUS DNA END JOINING; NUCLEIC ACID; NUCLEIC ACID ENZYMOLOGY; NUCLEIC ACID STRUCTURE; PROTEIN DNA-INTERACTION;

CHROMATOGRAPHY; CIRCULAR DICHROISM; DEOXYRIBONUCLEASE I; DNA; DNA END-JOINING REPAIR; EXODEOXYRIBONUCLEASES; HEK293 CELLS; HUMANS; MUTAGENESIS; NUCLEAR PROTEINS; NUCLEOTIDASES; OLIGONUCLEOTIDES; POINT MUTATION; TRANSFECTION;

EID: 84896289647     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.544874     Document Type: Article

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