Diagnostic vitrectomy for infectious uveitis

International Ophthalmology Clinics

Volumn 54, Issue 2, 2014, Pages 173-197

  Jeroudi, Abdallah ^a   Yeh, Steven ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY PRODUCTION; ANTIBODY TITER; AQUEOUS HUMOR; ARTICLE; BACTERIAL ENDOPHTHALMITIS; BACTERIUM CULTURE; BIOPSY FORCEPS; BLOOD EYE BARRIER; CHORIORETINAL BIOPSY; CILIARY DISK; CONNECTIVE TISSUE DISEASE; DIAGNOSTIC VALUE; DIAGNOSTIC VITRECTOMY; ENDOLASER; ENDOPHTHALMITIS; EYE BIOPSY; EYE INFECTION; EYE TUMOR; FUNGAL ENDOPHTHALMITIS; FUNGUS CULTURE; GRAFT RECIPIENT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTIOUS UVEITIS; INTRAOCULAR LYMPHOMA; INTRAOCULAR PRESSURE; MASQUERADE SYNDROME; METASTASIS; MYCOBACTERIUM TUBERCULOSIS; NOCARDIOSIS; OCULAR TOXOCARIASIS; OCULAR TUBERCULOSIS; PARS PLANA VITRECTOMY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETINA DETACHMENT; SCLEROTOMY; SYSTEMIC LUPUS ERYTHEMATOSUS; TOXOCARA CANIS; TOXOCARIASIS; TOXOPLASMA GONDII; TOXOPLASMOSIS; UVEA MELANOMA; UVEITIS; VITRECTOMY; VITREOUS BODY; VITRITIS;

DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC TECHNIQUES, OPHTHALMOLOGICAL; EYE INFECTIONS; HUMANS; REPRODUCIBILITY OF RESULTS; UVEITIS; VITRECTOMY; VITREOUS BODY;

EID: 84896273837     PISSN: 00208167     EISSN: 15369617     Source Type: Journal    
DOI: 10.1097/IIO.0000000000000017     Document Type: Article

References (150)

1. Carroll DM, Franklin RM. Vitreous biopsy in uveitis of unknown cause. Retina. 1981;1:245-251
2. Priem H, Verbraeken H, De Laey JJ. Diagnostic problems in chronic vitreous inflammation. Graefes Arch Clin Exp Ophthalmol. 1993;231:453-456
3. Palexas GN, Green WR, Goldberg MF, et al. Diagnostic pars plana vitrectomy report of a 21-year retrospective study. Trans Am Ophthalmol Soc. 1995;93:281-308
4. Verbraeken H. Diagnostic vitrectomy and chronic uveitis. Graefes Arch Clin Exp Ophthalmol. 1996;234:S2-S7
5. Akpek EK, Ahmed I, Hochberg FH, et al. Intraocular-central nervous system lymphoma: Clinical features, diagnosis, and outcomes. Ophthalmology. 1999;106: 1805-1810
6. Mruthyunjaya P, Jumper JM, McCallum R, et al. Diagnostic yield of vitrectomy in eyes with suspected posterior segment infection or malignancy. Ophthalmology. 2002;109:1123-1129
7. Coupland SE, Bechrakis NE, Anastassiou G, et al. Evaluation of vitrectomy specimens and chorioretinal biopsies in the diagnosis of primary intraocular lymphoma in patients with Masquerade syndrome. Graefes Arch Clin Exp Ophthalmol. 2003;241:860-870
8. Zaldivar RA, Martin DF, Holden JT, et al. Primary intraocular lymphoma: Clinical, cytologic, and flow cytometric analysis. Ophthalmology. 2004;111:1762-1767
9. Davis JL, Miller DM, Ruiz P. Diagnostic testing of vitrectomy specimens. Am J Ophthalmol. 2005;140:822-829
10. Margolis R, Brasil OF, Lowder CY, et al. Vitrectomy for the diagnosis and management of uveitis of unknown cause. Ophthalmology. 2007;114:1893-1897
11. Wittenberg LA, Maberley DA, Ma PE, et al. Contribution of vitreous cytology to final clinical diagnosis fifteen-year review of vitreous cytology specimens from one institution. Ophthalmology. 2008;115:1944-1950
12. Oahalou A, Schellekens PA, De Groot-Mijnes JD, et al. Diagnostic pars plana vitrectomy and aqueous analyses in patients with uveitis of unknown cause. Retina. 2014;34:108-114
13. Jabs DA, Nussenblatt RB, Rosenbaum JT. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. 2005;140:509-516
14. Rosenbaum JT,Wernick R. The utility of routine screening of patients with uveitis for systemic lupus erythematosus or tuberculosis. A Bayesian analysis. Arch Ophthalmol. 1990;108:1291-1293
15. Davis JL. Diagnostic dilemmas in retinitis and endophthalmitis. Eye (Lond). 2012;26:194-201
16. Conlon MR, Craig I, Harris JF, et al. Effect of vitrectomy and cytopreparatory techniques on cell survival and preservation. Can J Ophthalmol. 1992;27:168-171
17. Margolis R. Diagnostic vitrectomy for the diagnosis and management of posterior uveitis of unknown etiology. Curr Opin Ophthalmol. 2008;19:218-224
18. Bechrakis NE, Foerster MH, Bornfeld N. Biopsy in indeterminate intraocular tumors. Ophthalmology. 2002;109:235-242
19. Johnston RL, Tufail A, Lightman S, et al. Retinal and choroidal biopsies are helpful in unclear uveitis of suspected infectious or malignant origin. Ophthalmology. 2004; 111:522-528
20. Peyman GA, Juarez CP, Raichand M. Full-Thickness eye-wall biopsy: Long-Term results in 9 patients. Br J Ophthalmol. 1981;65:723-726
21. Martin DF, Chan CC, De Smet MD, et al. The role of chorioretinal biopsy in the management of posterior uveitis. Ophthalmology. 1993;100:705-714
22. Cassoux N, Charlotte F, Rao NA, et al. Endoretinal biopsy in establishing the diagnosis of uveitis: A clinicopathologic report of three cases. Ocul Immunol Inflamm. 2005;13:79-83
23. Kvanta A, Seregard S, Kopp ED, et al. Choroidal biopsies for intraocular tumors of indeterminate origin. Am J Ophthalmol. 2005;140:1002-1006
24. Lim LL, Suhler EB, Rosenbaum JT, et al. The role of choroidal and retinal biopsies in the diagnosis and management of atypical presentations of uveitis. Trans Am Ophthalmol Soc. 2005;103:84-92
25. Cole CJ, Kwan AS, Laidlaw DA, et al. A new technique of combined retinal and choroidal biopsy. Br J Ophthalmol. 2008;92:1357-1360
26. Seregard S, All-Ericsson C, Hjelmqvist L, et al. Diagnostic incisional biopsies in clinically indeterminate choroidal tumours. Eye (Lond). 2013;27:115-118
27. Bispo PJ, Melo GB, d'Azevedo PA, et al. Culture proven bacterial endophthalmitis: A 6-year review. Arq Bras Oftalmol. 2008;71:617-622
28. Han DP, Wisniewski SR, Kelsey SF, et al. Microbiologic yields and complication rates of vitreous needle aspiration versus mechanized vitreous biopsy in the Endophthalmitis Vitrectomy Study. Retina. 1999;19:98-102
29. Okhravi N, Adamson P, Carroll N, et al. PCR-based evidence of bacterial involvement in eyes with suspected intraocular infection. Invest Ophthalmol Vis Sci. 2000;41: 3474-3479
30. Chan RY, Yannuzzi LA, Foster CS. Ocular Whipple's disease: Earlier definitive diagnosis. Ophthalmology. 2001;108:2225-2231
31. Chiquet C, Lina G, Benito Y, et al. Polymerase chain reaction identification in aqueous humor of patients with postoperative endophthalmitis. J Cataract Refract Surg. 2007;33:635-641
32. Chiquet C, Maurin M, Thuret G, et al. Analysis of diluted vitreous samples from vitrectomy is useful in eyes with severe acute postoperative endophthalmitis. Ophthalmology. 2009;116:2437-2441, e1
33. Joseph CR, Lalitha P, Sivaraman KR, et al. Real-Time polymerase chain reaction in the diagnosis of acute postoperative endophthalmitis. Am J Ophthalmol. 2012;153: 1031-1037
34. Sugita S, Shimizu N, Watanabe K, et al. Diagnosis of bacterial endophthalmitis by broad-range quantitative PCR. Br J Ophthalmol. 2011;95:345-349
35. Bispo PJ, De Melo GB, Hofling-Lima AL, et al. Detection and gram discrimination of bacterial pathogens from aqueous and vitreous humor using real-Time PCR assays. Invest Ophthalmol Vis Sci. 2011;52:873-881
36. Gupta V, Gupta A, Rao NA. Intraocular tuberculosis-An update. Surv Ophthalmol. 2007;52:561-587
37. Vasconcelos-Santos DV, Zierhut M, Rao NA. Strengths and weaknesses of diagnostic tools for tuberculous uveitis. Ocul Immunol Inflamm. 2009;17:351-355
38. Biswas J, Madhavan HN, Gopal L, et al. Intraocular tuberculosis. Clinicopathologic study of five cases. Retina. 1995;15:461-468
39. Yeh S, Sen HN, Colyer M, et al. Update on ocular tuberculosis. Curr Opin Ophthalmol. 2012;23:551-556
40. Arora SK, Gupta V, Gupta A, et al. Diagnostic efficacy of polymerase chain reaction in granulomatous uveitis. Tuber Lung Dis. 1999;79:229-233
41. Gupta V, Arora S, Gupta A, et al. Management of presumed intraocular tuberculosis: Possible role of the polymerase chain reaction. Acta Ophthalmol Scand. 1998;76: 679-682
42. Gupta A, Gupta V, Arora S, et al. PCR-positive tubercular retinal vasculitis: Clinical characteristics and management. Retina. 2001;21:435-444
43. Gupta V, Gupta A, Arora S, et al. Presumed tubercular serpiginouslike choroiditis: Clinical presentations and management. Ophthalmology. 2003;110:1744-1749
44. Ortega-Larrocea G, Bobadilla-del-Valle M, Ponce-de-Leon A, et al. Nested polymerase chain reaction for Mycobacterium tuberculosis DNA detection in aqueous and vitreous of patients with uveitis. Arch Med Res. 2003;34:116-119
45. Lalitha P, Rajagopalan J, Prakash K, et al. Postcataract endophthalmitis in South India incidence and outcome. Ophthalmology. 2005;112:1884-1889
46. Scott M, Mehta S, Rahman HT, et al. Nocardia veterana endogenous endophthalmitis in a cardiac transplant patient. J Ophthalmic Inflamm Infect. 2013;3:44
47. Haripriya A, Lalitha P, Mathen M, et al. Nocardia endophthalmitis after cataract surgery: Clinicomicrobiological study. Am J Ophthalmol. 2005;139:837-846
48. Manikandan P, Bhaskar M, Revathi R, et al. Isolation and antimicrobial susceptibility pattern of Nocardia among people with culture-proven ocular infections attending a tertiary care eye hospital in Tamilnadu, South India. Eye (Lond). 2007;21:1102-1108
49. Errera MH, Goldschmidt P, Batellier L, et al. Real-Time polymerase chain reaction and intraocular antibody production for the diagnosis of viral versus toxoplasmic infectious posterior uveitis. Graefes Arch Clin Exp Ophthalmol. 2011;249:1837-1846
50. Eschle-Meniconi ME, Guex-Crosier Y, Wolfensberger TJ. Endogenous ocular nocardiosis: An interventional case report with a review of the literature. Surv Ophthalmol. 2011;56:383-415
51. DeCroos FC, Garg P, Reddy AK, et al. Optimizing diagnosis and management of nocardia keratitis, scleritis, and endophthalmitis: 11-year microbial and clinical overview. Ophthalmology. 2011;118:1193-1200
52. Davitt B, Gehrs K, Bowers T. Endogenous Nocardia endophthalmitis. Retina. 1998; 18:71-73
53. Azap A, Arslan H, Ergin F, et al. Disseminated Nocardia asteroides and coinfection with Trichophyton rubrum in a renal transplant recipient. Transpl Infect Dis. 2002;4:223-225
54. Ng EW, Zimmer-Galler IE, Green WR. Endogenous Nocardia asteroides endophthalmitis. Arch Ophthalmol. 2002;120:210-213
55. De Silva T, Evans C, Mudhar HS, et al. Isolated endogenous endophthalmitis secondary to Nocardia spp in an immunocompetent adult. J Clin Pathol. 2006;59: 1226
56. Sher NA, Hill CW, Eifrig DE. Bilateral intraocular Nocardia asteroides infection. Arch Ophthalmol. 1977;95:1415-1418
57. Ishibashi Y, Watanabe R, Hommura S, et al. Endogenous Nocardia asteroides endophthalmitis in a patient with systemic lupus erythematosus. Br J Ophthalmol. 1990;74:433-436
58. Pelayes DE, Colombero D, Gioino JM, et al. Endogenous Nocardia asteroides endophthalmitis in a patient with systemic lupus erythematosus. Medicina (B Aires). 2004;64:146-148
59. Dodds EM, Echandi LV, Puente SI, et al. Subretinal abscess due to Nocardia farcinica resistant to trimethoprim-sulfamethoxazole in a patient with systemic lupus erythematosus. Ocul Immunol Inflamm. 2006;14:249-251
60. Zaatreh M, Alabulkarim W. Images in clinical medicine. Disseminated central nervous system nocardiosis. N Engl J Med. 2006;354:2802
61. Chen LY, Kesen MR, Ghafourian A, et al. Isolated endogenous Nocardia endophthalmitis after immunosuppression. J Ophthalmic Inflamm Infect. 2012;2:141-143
62. Yu E, Laughlin S, Kassel EE, et al. Nocardial endophthalmitis and subretinal abscess: CT and MR imaging features with pathologic correlation: A case report. AJNR Am J Neuroradiol. 2005;26:1220-1222
63. Gregor RJ, Chong CA, Augsburger JJ, et al. Endogenous Nocardia asteroides subretinal abscess diagnosed by transvitreal fine-needle aspiration biopsy. Retina. 1989;9:118-121
64. Knouse MC, Lorber B. Early diagnosis of Nocardia asteroides endophthalmitis by retinal biopsy: Case report and review. Rev Infect Dis. 1990;12:393-398
65. Phillips WB, Shields CL, Shields JA, et al. Nocardia choroidal abscess. Br J Ophthalmol. 1992;76:694-696
66. Bozbeyoglu S, Yilmaz G, Akova YA, et al. Choroidal abscess due to nocardial infection in a renal allograft recipient. Retina. 2004;24:164-166
67. Yin X, Liang S, Sun X, et al. Ocular nocardiosis: HSP65 gene sequencing for species identification of Nocardia spp. Am J Ophthalmol. 2007;144:570-573
68. Johnson MW, Greven GM, Jaffe GJ, et al. Atypical, severe toxoplasmic retinochoroiditis in elderly patients. Ophthalmology. 1997;104:48-57
69. Moshfeghi DM, Dodds EM, Couto CA, et al. Diagnostic approaches to severe, atypical toxoplasmosis mimicking acute retinal necrosis. Ophthalmology. 2004;111:716-725
70. Miller D, Davis J, Rosa R, et al. Utility of tissue culture for detection of Toxoplasma gondii in vitreous humor of patients diagnosed with toxoplasmic retinochoroiditis. J Clin Microbiol. 2000;38:3840-3842
71. Figueroa MS, Bou G, Marti-Belda P, et al. Diagnostic value of polymerase chain reaction in blood and aqueous humor in immunocompetent patients with ocular toxoplasmosis. Retina. 2000;20:614-619, 1
72. Bou G, Figueroa MS, Marti-Belda P, et al. Value of PCR for detection of Toxoplasma gondii in aqueous humor and blood samples from immunocompetent patients with ocular toxoplasmosis. J Clin Microbiol. 1999;37:3465-3468
73. Garweg JG, Jacquier P, Boehnke M. Early aqueous humor analysis in patients with human ocular toxoplasmosis. J Clin Microbiol. 2000;38:996-1001
74. Labalette P, Delhaes L, Margaron F, et al. Ocular toxoplasmosis after the fifth decade. Am J Ophthalmol. 2002;133:506-515
75. Fardeau C, Romand S, Rao NA, et al. Diagnosis of toxoplasmic retinochoroiditis with atypical clinical features. Am J Ophthalmol. 2002;134:196-203
76. Lee SE, Hong SH, Lee SH, et al. Detection of ocular Toxoplasma gondii infection in chronic irregular recurrent uveitis by PCR. Korean J Parasitol. 2012;50:229-231
77. Montoya JG, Parmley S, Liesenfeld O, et al. Use of the polymerase chain reaction for diagnosis of ocular toxoplasmosis. Ophthalmology. 1999;106:1554-1563
78. Fekkar A, Bodaghi B, Touafek F, et al. Comparison of immunoblotting, calculation of the Goldmann-Witmer coefficient, and real-Time PCR using aqueous humor samples for diagnosis of ocular toxoplasmosis. J Clin Microbiol. 2008;46:1965-1967
79. Talabani H, Asseraf M, Yera H, et al. Contributions of immunoblotting, real-Time PCR, and the Goldmann-Witmer coefficient to diagnosis of atypical toxoplasmic retinochoroiditis. J Clin Microbiol. 2009;47:2131-2135
80. Santos FF, Commodaro AG, Souza AV, et al. Real-Time PCR in infectious uveitis as an alternative diagnosis. Arq Bras Oftalmol. 2011;74:258-261
81. Uy HS, Foster CS. Diagnostic vitrectomy and uveitis. Int Ophthalmol Clin. 1999;39: 223-235
82. Rothova A, De Boer JH, Ten Dam-van Loon NH, et al. Usefulness of aqueous humor analysis for the diagnosis of posterior uveitis. Ophthalmology. 2008;115:306-311
83. De Groot-Mijnes JD, Rothova A, Van Loon AM, et al. Polymerase chain reaction and Goldmann-Witmer coefficient analysis are complimentary for the diagnosis of infectious uveitis. Am J Ophthalmol. 2006;141:313-318
84. Westeneng AC, Rothova A, De Boer JH, et al. Infectious uveitis in immunocompromised patients and the diagnostic value of polymerase chain reaction and Goldmann-Witmer coefficient in aqueous analysis. Am J Ophthalmol. 2007;144:781-785
85. Matos K, Muccioli C, Belfort Junior R, et al. Correlation between clinical diagnosis and PCR analysis of serum, aqueous, and vitreous samples in patients with inflammatory eye disease. Arq Bras Oftalmol. 2007;70:109-114
86. Sugita S, Shimizu N, Watanabe K, et al. Use of multiplex PCR and real-Time PCR to detect human herpes virus genome in ocular fluids of patients with uveitis. Br J Ophthalmol. 2008;92:928-932
87. Harper TW, Miller D, Schiffman JC, et al. Polymerase chain reaction analysis of aqueous and vitreous specimens in the diagnosis of posterior segment infectious uveitis. Am J Ophthalmol. 2009;147:140-147
88. Schneier AJ, Durand ML. Ocular toxocariasis: Advances in diagnosis and treatment. Int Ophthalmol Clin. 2011;51:135-144
89. De Visser L, Rothova A, De Boer JH, et al. Diagnosis of ocular toxocariasis by establishing intraocular antibody production. Am J Ophthalmol. 2008;145:369-374
90. Stewart JM, Cubillan LD, Cunningham ET Jr. Prevalence, clinical features, and causes of vision loss among patients with ocular toxocariasis. Retina. 2005;25:1005-1013
91. Yokoi K, Goto H, Sakai J, et al. Clinical features of ocular toxocariasis in Japan. Ocul Immunol Inflamm. 2003;11:269-275
92. Acar N, Kapran Z, Utine CA, et al. Pars plana vitrectomy revealed Toxocara canis organism. Int Ophthalmol. 2007;27:277-280
93. Gonvers M, Mermoud A, Uffer S, et al. Ocular Toxocara canis in a 30-year-old adult. Klin Monbl Augenheilkd. 1992;200:522-524
94. Amin HI, McDonald HR, Han DP, et al. Vitrectomy update for macular traction in ocular toxocariasis. Retina. 2000;20:80-85
95. Maguire AM, Green WR, Michels RG, et al. Recovery of intraocular Toxocara canis by pars plana vitrectomy. Ophthalmology. 1990;97:675-680
96. Werner JC, Ross RD, Green WR, et al. Pars plana vitrectomy and subretinal surgery for ocular toxocariasis. Arch Ophthalmol. 1999;117:532-534
97. Meyer-Riemann W, Petersen J, Vogel M. An attempt to extract an intraretinal nematode located in the papillomacular bundle. Klin Monbl Augenheilkd. 1999;214: 116-119
98. De Souza EC, Nakashima Y. Diffuse unilateral subacute neuroretinitis. Report of transvitreal surgical removal of a subretinal nematode. Ophthalmology. 1995;102:1183-1186
99. Felberg NT, Shields JA, Federman JL. Antibody to Toxocara canis in the aqueous humor. Arch Ophthalmol. 1981;99:1563-1564
100. Benitez Del Castillo JM, Herreros G, Guillen JL, et al. Bilateral ocular toxocariasis demonstrated by aqueous humor enzyme-linked immunosorbent assay. Am J Ophthalmol. 1995;119:514-516
101. Yoshida M, Shirao Y, Asai H, et al. A retrospective study of ocular toxocariasis in Japan: Correlation with antibody prevalence and ophthalmological findings of patients with uveitis. J Helminthol. 1999;73:357-361
102. Alabiad CR, Albini TA, Santos CI, et al. Ocular toxocariasis in a seronegative adult. Ophthalmic Surg Lasers Imaging. 2010;41:1-3
103. Hagler WS, Pollard ZF, Jarrett WH, et al. Results of surgery for ocular Toxocara canis. Ophthalmology. 1981;88:1081-1086
104. Lim SJ, Lee SE, Kim SH, et al. Prevalence of Toxoplasma gondii and Toxocara canis among patients with uveitis. Ocul Immunol Inflamm. 2013. Doi:10.3109/ 09273948.2013.839798. [Epub ahead of print
105. Fox GM, Crouse CA, Chuang EL, et al. Detection of herpesvirus DNA in vitreous and aqueous specimens by the polymerase chain reaction. Arch Ophthalmol. 1991; 109:266-271
106. Pendergast SD, Werner J, Drevon A, et al. Absence of herpesvirus DNA by polymerase chain reaction in ocular fluids obtained from immunocompetent patients. Retina. 2000;20:389-393
107. Abe T, Tsuchida K, Tamai M. A comparative study of the polymerase chain reaction and local antibody production in acute retinal necrosis syndrome and cytomegalovirus retinitis. Graefes Arch Clin Exp Ophthalmol. 1996;234:419-424
108. Pavesio CE, Mitchell SM, Barton K, et al. Progressive outer retinal necrosis (PORN) in AIDS patients: A different appearance of varicella-zoster retinitis. Eye (Lond). 1995;9:271-276
109. Itoh N, Matsumura N, Ogi A, et al. High prevalence of herpes simplex virus type 2 in acute retinal necrosis syndrome associated with herpes simplex virus in Japan. Am J Ophthalmol. 2000;129:404-405
110. Ganatra JB, Chandler D, Santos C, et al. Viral causes of the acute retinal necrosis syndrome. Am J Ophthalmol. 2000;129:166-172
111. Tran TH, Rozenberg F, Cassoux N, et al. Polymerase chain reaction analysis of aqueous humour samples in necrotising retinitis. Br J Ophthalmol. 2003;87:79-83
112. Yeh S, Fahle G, Forooghian F, et al. Polymerase chain reaction-based ganciclovir resistance testing of ocular fluids for cytomegalovirus retinitis. Arch Ophthalmol. 2012;130:113-115
113. Read RW, Zamir E, Rao NA. Neoplastic masquerade syndromes. Surv Ophthalmol. 2002;47:81-124
114. Tsai T, O'Brien JM. Masquerade syndromes: Malignancies mimicking inflammation in the eye. Int Ophthalmol Clin. 2002;42:115-131
115. Rothova A, Ooijman F, Kerkhoff F, et al. Uveitis masquerade syndromes. Ophthalmology. 2001;108:386-399
116. Davis JL, Viciana AL, Ruiz P. Diagnosis of intraocular lymphoma by flow cytometry. Am J Ophthalmol. 1997;124:362-372
117. Davis JL. Intraocular lymphoma: A clinical perspective. Eye (Lond). 2013;27: 153-162
118. Yap EY, Robertson DM, Buettner H. Scleritis as an initial manifestation of choroidal malignant melanoma. Ophthalmology. 1992;99:1693-1697
119. Moshari A, Cheeseman EW, McLean IW. Totally necrotic choroidal and ciliary body melanomas: Associations with prognosis, episcleritis, and scleritis. Am J Ophthalmol. 2001;131:232-236
120. Kafkala C, Daoud YJ, Paredes I, et al. Masquerade scleritis. Ocul Immunol Inflamm. 2005;13:479-482
121. Palamar M, Thangappan A, Shields CL, et al. Necrotic choroidal melanoma with scleritis and choroidal effusion. Cornea. 2009;28:354-356
122. Martin B. Diffuse malignant melanoma of the iris. Trans Ophthalmol Soc U K. 1973;93: 473-475
123. al-Haddab S, Hidayat A, Tabbara KF. Ciliary body melanoma with optic nerve invasion. Br J Ophthalmol. 1990;74:123-124
124. Mathew B, Brownstein S, Kertes PJ, et al. Clinically unsuspected diffuse uveal melanoma presenting as recurrent iritis. Can J Ophthalmol. 2004;39:464-467
125. Kearns C, Boyer S, Gay D. Two differing presentations, treatments, and outcomes of malignant choroidal melanoma. Optometry. 2008;79:365-370
126. Nagpal A, Biswas J. Pseudouveitis-Analysis of cases misdiagnosed as posterior uveitis. Ocul Immunol Inflamm. 2006;14:13-20
127. Nguyen QD, Foster CS. Ciliary body melanoma masquerading as chronic uveitis. Ocul Immunol Inflamm. 1998;6:253-256
128. Sood NN, Ratnaraj A. Malignant melanoma of choroid presenting as panophthalmitis. J All India Ophthalmol Soc. 1968;16:67-69
129. Kline LB, Bright M, Brownstein S. Uveal melanoma presenting as post-Traumatic choroidal hemorrhage and panophthalmitis. Can J Ophthalmol. 1977;12:226-229
130. Pizzuto D, deLuise V, Zimmerman N. Choroidal malignant melanoma appearing as acute panophthalmitis. Am J Ophthalmol. 1986;101:249-251
131. Fraser DJ Jr, Font RL. Ocular inflammation and hemorrhage as initial manifestations of uveal malignant melanoma. Incidence and prognosis. Arch Ophthalmol. 1979;97:1311-1314
132. Kavanagh MC, Everman KR, Opremcak EM, et al. Uveal melanoma with massive extrascleral extension via pars plana vitrectomy sites. Ophthal Plast Reconstr Surg. 2008;24:334-336
133. Sakuma T, Iseki R, Mimura A, et al. Rapid cytologic diagnosis of choroidal malignant melanoma by vitreous smear. J Fr Ophtalmol. 2012;35:535.e1-535.e4
134. Shields CL, Ganguly A, Materin MA, et al. Chromosome 3 analysis of uveal melanoma using fine-needle aspiration biopsy at the time of plaque radiotherapy in 140 consecutive cases. Trans Am Ophthalmol Soc. 2007;105:43-53
135. Bagger M, Tebering JF, Kiilgaard JF. The ocular consequences and applicability of minimally invasive 25-gauge transvitreal retinochoroidal biopsy. Ophthalmology. 2013;120:2565-2572
136. Schefler AC, Gologorsky D, Marr BP, et al. Extraocular extension of uveal melanoma after fine-needle aspiration, vitrectomy, and open biopsy. JAMA Ophthalmol. 2013; 131:1220-1224
137. Talegaonkar SK. Anterior uveal tract metastasis as the presenting feature of bronchial carcinoma. Br J Ophthalmol. 1969;53:123-126
138. Morgan WE III, Malmgren RA, Albert DM. Metastatic carcinoma of the ciliary body simulating uveitis. Diagnosis by cytologic examination of aqueous humor. Arch Ophthalmol. 1970;83:54-58
139. Denslow GT, Kielar RA. Metastatic adenocarcinoma to the anterior uvea and increased carcinoembryonic antigen levels. Am J Ophthalmol. 1978;85:363-367
140. Scholz R, GreenWR, Baranano EC, et al.Metastatic carcinoma to the iris. Diagnosis by aqueous paracentesis and response to irradiation and chemotherapy. Ophthalmology. 1983;90:1524-1527
141. Takahashi T, Oda Y, Chiba T, et al. Metastatic carcinoma of the iris and ciliary body simulating iridocyclitis. Ophthalmologica. 1984;188:266-272
142. Woog JJ, Chess J, Albert DM, et al. Metastatic carcinoma of the iris simulating iridocyclitis. Br J Ophthalmol. 1984;68:167-173
143. Michelson JB, Grossman KR, Lozier JR, et al. Iridocyclitis masquerade syndrome. Surv Ophthalmol. 1986;31:125-130
144. Lieb WE, Shields JA, Shields CL, et al. Mucinous adenocarcinoma metastatic to the iris, ciliary body, and choroid. Br J Ophthalmol. 1990;74:373-376
145. Kesen MR, Edward DP, Ulanski LJ, et al. Pulmonary metastasis masquerading as anterior uveitis. Arch Ophthalmol. 2008;126:572-574
146. Iannetti L, Corsi C, Iafrate F, et al. Bilateral uveitis with hypopyon as a presenting symptom of metastatic peritoneal carcinomatosis. Eur J Ophthalmol. 2010;20: 948-951
147. Payne JF, Rahman HT, Grossniklaus HE, et al. Retinal metastasis simulating cytomegalovirus retinitis. Ophthalmic Surg Lasers Imaging. 2012;43:e90-e93
148. Jaissle GB, Szurman P, Rohrbach JM, et al. A case of cutaneous melanoma metastatic to the vitreous cavity: Possible pathomechanism and review of the literature. Graefes Arch Clin Exp Ophthalmol. 2007;245:733-740
149. Konstantinidis L, Rospond-Kubiak I, Zeolite I, et al. Management of patients with uveal metastases at the Liverpool Ocular Oncology Centre. Br J Ophthalmol. 2014;98:92-98
150. Shields JA, Shields CL, Ehya H, et al. Fine-needle aspiration biopsy of suspected intraocular tumors. The 1992 Urwick Lecture. Ophthalmology. 1993;100:1677-1684