Polymerase Chain Reaction Analysis of Aqueous and Vitreous Specimens in the Diagnosis of Posterior Segment Infectious Uveitis

American Journal of Ophthalmology

Volumn 147, Issue 1, 2009, Pages

  Harper, Thomas W ^a   Miller, Darlene ^a   Schiffman, Joyce C ^a   Davis, Janet L ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AQUEOUS HUMOR; ARTICLE; CHORIORETINITIS; CLINICAL FEATURE; CYTOMEGALOVIRUS; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; EPSTEIN BARR VIRUS; FEMALE; HERPES SIMPLEX VIRUS; HUMAN; IMMUNOCOMPROMISED PATIENT; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OPTIC NERVE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TOXOPLASMOSIS; UVEITIS; VARICELLA ZOSTER VIRUS; VITREOUS BODY;

EID: 57549094491     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2008.07.043     Document Type: Article

References (20)

1. Van Gelder R.N. CME review: polymerase chain reaction diagnostics for posterior segment disease. Retina 23 (2003) 445-452
2. Fox G.M., Crouse C.A., Chuang E., et al. Detection of herpesvirus DNA in vitreous and aqueous specimens by the polymerase chain reaction. Arch Ophthalmol 109 (1991) 266-271
3. de Boer J.H., Verhagen C., Bruinenberg M., et al. Serologic and polymerase chain reaction analysis of intraocular fluids in the diagnosis of infectious uveitis. Am J Ophthalmol 121 (1996) 650-658
4. Abe T., Tsuchida K., and Tamai M. A comparative study of the polymerase chain reaction and local antibody production in acute retinal necrosis syndrome and cytomegalovirus retinitis. Graefes Arch Clin Exp Ophthalmol 234 (1996) 419-424
5. Cunningham E.T., Short G.A., Irvine A.R., Duker J.S., and Margolis T.P. Acquired immunodeficiency syndrome-associated herpes simplex virus retinitis. Clinical description and use of a polymerase chain reaction-based assay as a diagnostic tool. Arch Ophthalmol 114 (1996) 834-840
6. McCann J.D., Margolis T.P., Wong M.G., et al. A sensitive and specific polymerase chain reaction-based assay for the diagnosis of cytomegalovirus retinitis. Am J Ophthalmol 120 (1995) 219-226
7. Short G.A., Margolis T.P., Kuppermann B.D., Irvine A.R., Martin D.F., and Chandler D. A polymerase chain reaction-based assay for the diagnosis of varicella-zoster virus retinitis in patients with AIDS. Am J Ophthalmol 123 (1997) 157-164
8. Pendergast S.D., Werner J., Drevon A., and Wiedbrauk D.L. Absence of herpes virus DNA by polymerase chain reaction in ocular fluids obtained from immunocompetent patients. Retina 20 (2000) 389-393
9. Davis J.L., Miller D.M., and Ruiz P. Diagnostic testing of vitrectomy specimens. Am J Ophthalmol 140 (2005) 822-829
10. Miller D., Davis J., Rosa R., Diaz M., and Perez E. Utility of tissue culture for detection of Toxoplasma gondii in vitreous humor of patients diagnosed with toxoplasmic chorioretinitis. J Clin Microbiol 38 (2000) 3840-3842
11. De Groot-Mijnes J.D., Rothova A., van Loon A.M., et al. Polymerase chain reaction and Goldmann-Witmer coefficient analysis are complimentary for the diagnosis of infectious uveitis. Am J Ophthalmol 141 (2006) 313-318
12. Davies N.W.S., Brown L.J., Gonde J., et al. Factors influencing PCR detection of viruses in cerebrospinal fluid of patients with suspected CNS infections. J Neurol Neurosurg Psychiatry 76 (2005) 82-87
13. Rothova A., de Boer J.H., Ten Dam-van Loon N.H., et al. Usefulness of aqueous humor analysis for the diagnosis of posterior uveitis. Ophthalmology 115 (2008) 306-311
14. Tran T.H., Rozenberg F., Cassoux N., Rao N.A., Lehoang P., and Bodaghi B. Polymerase chain reaction analysis of aqueous humour samples in necrotizing retinitis. Br J Ophthalmol 87 (2003) 79-83
15. Montoya J.G., Parmley S., Liesenfeld O., Jaffe G.J., and Remington J.S. Use of the polymerase chain reaction for diagnosis of ocular toxoplasmosis. Ophthalmology 106 (1999) 1554-1563
16. Fardeau C., Romand S., Rao N.A., et al. Diagnosis of toxoplasmic retinochoroiditis with atypical clinical features. Am J Ophthalmol 134 (2002) 196-203
17. Labalette P., Delhaes L., Margaron F., Fortier B., and Rouland J. Ocular toxoplasmosis after the fifth decade. Am J Ophthalmol 133 (2002) 506-515
18. Westeneng A.C., Rothova A., de Boer J.H., and de Groot-Mijnes J.D.F. Infectious uveitis in immunocompromised patients and the diagnostic value of polymerase chain reaction and Goldmann-Witmer coefficient in aqueous analysis. Am J Ophthalmol 144 (2007) 781-785
19. Moshfeghi D.M., Dodds E.M., Couto C.A., et al. Diagnostic approaches to severe, atypical toxoplasmosis mimicking acute retinal necrosis. Ophthalmology 111 (2004) 716-725
20. Sugita S., Shimizu N., Watanabe K., et al. Use of multiplex PCR and real-time PCR to detect human herpes virus genome in ocular fluids of patients with uveitis. Br J Ophthalmol 92 (2008) 928-932