Smoking is not associated with autoantibody production in systemic lupus erythematosus patients, unaffected first-degree relatives, nor healthy controls

Lupus

Volumn 23, Issue 4, 2014, Pages 360-369

  Young, K A ^a   Terrell, D R ^b   Guthridge, J M ^c   Kamen, D L ^d   Gilkeson, G S ^d   Karp, D R ^e   Ishimori, M L ^f   Weisman, M H ^f   Holers, V M ^g   Harley, J B ^h   Norris, J M ^a   James, J A ^c,i  

^a Global Health and Health Disparities   (United States)

^b Oklahoma University Health Science Center   (United States)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f CEDARS SINAI MEDICAL CENTER   (United States)

^g UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^h Children's Medical Center   (United States)

ⁱ UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

autoantibodies; Smoking; systemic lupus erythematosus

Indexed keywords

AUTOANTIBODY; NUCLEAR RIBONUCLEOPROTEIN 68; SMALL NUCLEAR RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG; ANTINUCLEAR ANTIBODY;

ADULT; AGED; ANTIBODY PRODUCTION; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FIRST DEGREE RELATIVE; HUMAN; IMMUNOFLUORESCENCE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OUTCOME VARIABLE; PRIORITY JOURNAL; QUESTIONNAIRE; RISK FACTOR; SMOKING; SYSTEMIC LUPUS ERYTHEMATOSUS; CASE CONTROL STUDY; FAMILY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY;

ADULT; ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; CASE-CONTROL STUDIES; FAMILY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; QUESTIONNAIRES; SMOKING;

EID: 84896129224     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203314520838     Document Type: Article

References (44)

1. Ghaussy NO, Sibbitt WL Jr, Qualls CR. Cigarette smoking, alcohol consumption, and the risk of systemic lupus erythematosus: A case-control study. J Rheumatol. 2001 ; 28: 2449-2453
2. Kiyohara C, Washio M, Horiuchi T, et al. Cigarette smoking, N-acetyltransferase 2 polymorphisms and systemic lupus erythematosus in a Japanese population. Lupus. 2009 ; 18: 630-638
3. Washio M, Horiuchi T, Kiyohara C, et al. Smoking, drinking, sleeping habits, and other lifestyle factors and the risk of systemic lupus erythematosus in Japanese females: Findings from the KYSS study. Mod Rheumatol. 2006 ; 16: 143-150
4. Hardy CJ, Palmer BP, Muir KR, Sutton AJ, Powell RJ. Smoking history, alcohol consumption, and systemic lupus erythematosus: A case-control study. Ann Rheum Dis. 1998 ; 57: 451-455
5. Kiyohara C, Washio M, Horiuchi T, et al. Cigarette smoking, alcohol consumption, and risk of systemic lupus erythematosus: A case-control study in a Japanese population. J Rheumatol. 2012 ; 39: 1363-1370
6. Nagata C, Fujita S, Iwata H, et al. Systemic lupus erythematosus: A case-control epidemiologic study in Japan. Int J Dermatol. 1995 ; 34: 333-337
7. Freemer MM, King TE Jr, Criswell LA. Association of smoking with dsDNA autoantibody production in systemic lupus erythematosus. Ann Rheum Dis. 2006 ; 65: 581-584
8. Karabulut G, Kitapcioglu G, Inal V, et al. Cigarette smoking in primary Sjögren's syndrome: Positive association only with ANA positivity. Mod Rheumatol. 2011 ; 21: 602-607
9. Heliovaara M, Aho K, Aromaa A, Knekt P, Reunanen A. Smoking and risk of rheumatoid arthritis. J Rheumatol. 1993 ; 20: 1830-1835
10. Klareskog L, Stolt P, Lundberg K, et al. A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis Rheum. 2006 ; 54: 38-46
11. Linn-Rasker SP, van der Helm-van Mil AH, van Gaalen FA, et al. Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles. Ann Rheum Dis. 2006 ; 65: 366-371
12. Mahdi H, Fisher BA, Källberg H, et al. Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis. Nat Gen. 2009 ; 41: 1319-1324
13. Masdottir B, Jónsson T, Manfredsdottir V, Víkingsson A, Brekkan A, Valdimarsson H. Smoking, rheumatoid factor isotypes and severity of rheumatoid arthritis. Rheumatology (Oxford). 2000 ; 39: 1202-1205
14. Mattey DL, Dawes PT, Clarke S, et al. Relationship among the HLA-DRB1 shared epitope, smoking, and rheumatoid factor production in rheumatoid arthritis. Arthritis Rheum. 2002 ; 47: 403-407
15. Michou L, Teixeira VH, Pierlot C, et al. Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis. Ann Rheum Dis. 2008 ; 67: 466-470
16. Pedersen M, Jacobsen S, Klarlund M, et al. Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides. Arthritis Res Ther. 2006 ; 8: R133 - R133
17. Uhlig T, Hagen KB, Kvien TK. Current tobacco smoking, formal education, and the risk of rheumatoid arthritis. J Rheumatol. 1999 ; 26: 47-54
18. van der Helm-van Mil AH, Verpoort KN, le Cessie S, Huizinga TW, de Vries RR, Toes RE. The HLA-DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide. Arthritis Rheum. 2007 ; 56: 425-432
19. Verpoort KN, Cheung K, Ioan-Facsinay A, et al. Fine specificity of the anti-citrullinated protein antibody response is influenced by the shared epitope alleles. Arthritis Rheum. 2007 ; 56: 3949-3952
20. Bijl M. Endothelial activation, endothelial dysfunction and premature atherosclerosis in systemic autoimmune diseases. Neth J Med. 2003 ; 61: 273-277
21. Kirkham PA, Spooner G, Rahman I, Rossi AG. Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products. Biochem Biophys Res Commun. 2004 ; 318: 32-37
22. Reefman E, Horst G, Nijk MT, Limburg PC, Kallenberg CG, Bijl M. Opsonization of late apoptotic cells by systemic lupus erythematosus autoantibodies inhibits their uptake via an Fcgamma receptor-dependent mechanism. Arthritis Rheum. 2007 ; 56: 3399-3411
23. Grimaldi CM, Cleary J, Dagtas AS, Moussai D, Diamond B. Estrogen alters thresholds for B cell apoptosis and activation. J Clin Invest. 2002 ; 109: 1625-1633
24. Lawrence JS, Martins CL, Drake GL. A family survey of lupus erythematosus. 1. Heritability. J Rheumatol. 1987 ; 14: 913-921
25. Deapen D, Escalante A, Weinrib L, et al. A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum. 1992 ; 35: 311-318
26. Alarcón-Segovia D, Alarcón-Riquelme ME, Cardiel MH, et al. Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort. Arthritis Rheum. 2005 ; 52: 1138-1147
27. Ramos PS, Kelly JA, Gray-McGuire C, et al. Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus. Genes Immun. 2006 ; 7: 417-432
28. Bruner BF, Guthridge JM, Lu R, et al. Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients with systemic lupus erythematosus and family members. Arthritis Rheum. 2012 ; 64: 3677-3686
29. Arbuckle MR, McClain MT, Rubertone MV, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med. 2003 ; 349: 1526-1533
30. Rasmussen A, Sevier S, Kelly JA, et al. The lupus family registry and repository. Rheumatology (Oxford). 2011 ; 50: 47-59
31. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997 ; 40: 1725-1725
32. Lu R, Robertson JM, Bruner BF, et al. Multiple autoantibodies display association with lymphopenia, proteinuria, and cellular casts in a large, ethnically diverse SLE patient cohort. Autoimmune Dis. 2012 ; 2012: 819634-819634
33. Rubin RL, Hermanson TM, Bedrick EJ, et al. Effect of cigarette smoke on autoimmunity in murine and human systemic lupus erythematosus. Toxicol Sci. 2005 ; 87: 86-96
34. Ghaussy NO, Sibbitt W Jr, Bankhurst AD, Qualls CR. Cigarette smoking and disease activity in systemic lupus erythematosus. J Rheumatol. 2003 ; 30: 1215-1221
35. Calvo-Alén J, Toloza SM, Fernández M, et al. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA). XXV. Smoking, older age, disease activity, lupus anticoagulant, and glucocorticoid dose as risk factors for the occurrence of venous thrombosis in lupus patients. Arthritis Rheum. 2005 ; 52: 2060-2068
36. Turchin I, Bernatsky S, Clarke AE, St-Pierre Y, Pineau CA. Cigarette smoking and cutaneous damage in systemic lupus erythematosus. J Rheumatol. 2009 ; 36: 2691-2693
37. Ward MM, Studenski S. Clinical prognostic factors in lupus nephritis. The importance of hypertension and smoking. Arch Intern Med. 1992 ; 152: 2082-2088
38. Heinlen LD, McClain MT, Ritterhouse LL, et al. 60 kD Ro and nRNP A frequently initiate human lupus autoimmunity. PloS One. 2010 ; 5: e9599 - e9599
39. Lee HS, Irigoyen P, Kern M, et al. Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: A mixed picture in three large North American rheumatoid arthritis cohorts. Arthritis Rheum. 2007 ; 56: 1745-1753
40. Willemze A, van der Woude D, Ghidey W, et al. The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens. Arthritis Rheum. 2011 ; 63: 1823-1832
41. Nizri E, Irony-Tur-Sinai M, Lory O, Orr-Urtreger A, Lavi E, Brenner T. Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses. J Immunol. 2009 ; 183: 6681-6688
42. Carrillo T, Rodriguez de Castro F, Cuevas M, Diaz F, Cabrera P. Effect of cigarette smoking on the humoral immune response in pigeon fanciers. Allergy. 1991 ; 46: 241-244
43. Pryor WA, Stone K, Zang LY, Bermúdez E. Fractionation of aqueous cigarette tar extracts: Fractions that contain the tar radical cause DNA damage. Chem Res Toxicol. 1998 ; 11: 441-448
44. Tanigawa T, Araki S, Nakata A, et al. Increase in memory (CD4+CD29+ and CD4+CD45RO+) T and naive (CD4+CD45RA+) T-cell subpopulations in smokers. Arch Environ Health. 1998 ; 53: 378-383