Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Olthof, Nadine C ^a   Speel, Ernst Jan M ^a   Kolligs, Jutta ^b   Haesevoets, Annick ^a   Henfling, Mieke ^a   Ramaekers, Frans C S ^a   Preuss, Simon F ^c   Drebber, Uta ^c   Wieland, Ulrike ^c   Silling, Steffi ^c   Lam, Wan L ^d   Vucic, Emily A ^d   Kremer, Bernd ^a   Klussmann, Jens P ^e   Huebbers, Christian U ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^d BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^e UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN E6; PROTEIN E7; ONCOPROTEIN; VIRUS DNA; VIRUS RNA;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; E2 GENE; E6 GENE; E7 GENE; FEMALE; GENE DISRUPTION; GENE DOSAGE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OROPHARYNGEAL SQUAMOUS CELL CARCINOMA; OROPHARYNX CARCINOMA; POLYMERASE CHAIN REACTION; VERY ELDERLY; VIRUS DNA CELL DNA INTERACTION; VIRUS ONCOGENE; GENETICS; MIDDLE AGED; OROPHARYNX TUMOR; PAPILLOMAVIRUS INFECTION; SQUAMOUS CELL CARCINOMA; VIRUS GENE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; DNA, VIRAL; FEMALE; GENE EXPRESSION; GENES, VIRAL; HUMAN PAPILLOMAVIRUS 16; HUMANS; MALE; MIDDLE AGED; ONCOGENE PROTEINS, VIRAL; OROPHARYNGEAL NEOPLASMS; PAPILLOMAVIRUS E7 PROTEINS; PAPILLOMAVIRUS INFECTIONS; RNA, MESSENGER; RNA, VIRAL; VIRUS INTEGRATION;

EID: 84896124922     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088718     Document Type: Article

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