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Volumn 131, Issue 5, 2012, Pages

Loss of gene function as a consequence of human papillomavirus DNA integration

Author keywords

HPV; Insertional mutagenesis; Loss of gene function; Viral integration

Indexed keywords

MESSENGER RNA;

EID: 84863215000     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27433     Document Type: Article
Times cited : (60)

References (44)
  • 2
    • 0028943423 scopus 로고
    • The presence of persistent high-risk HPV genotypes in dysplastic cervical lesions is associated with progressive disease: Natural history up to 36 months
    • Remmink AJ, Walboomers JM, Helmerhorst TJ, Voorhorst FJ, Rozendaal L, Risse EK, Meijer CJ, Kenemans P. The presence of persistent high-risk HPV genotypes in dysplastic cervical lesions is associated with progressive disease: natural history up to 36 months. Int J Cancer 1995;61: 306-11.
    • (1995) Int J Cancer , vol.61 , pp. 306-311
    • Remmink, A.J.1    Walboomers, J.M.2    Helmerhorst, T.J.3    Voorhorst, F.J.4    Rozendaal, L.5    Risse, E.K.6    Meijer, C.J.7    Kenemans, P.8
  • 4
    • 33645937963 scopus 로고    scopus 로고
    • Presence of E6 and E7 mRNA from human papillomavirus types 16, 18, 31, 33, and 45 in the majority of cervical carcinomas
    • Kraus I, Molden T, Holm R, Lie AK, Karlsen F, Kristensen GB, Skomedal H. Presence of E6 and E7 mRNA from human papillomavirus types 16, 18, 31, 33, and 45 in the majority of cervical carcinomas. J Clin Microbiol 2006;44:1310-7.
    • (2006) J Clin Microbiol , vol.44 , pp. 1310-1317
    • Kraus, I.1    Molden, T.2    Holm, R.3    Lie, A.K.4    Karlsen, F.5    Kristensen, G.B.6    Skomedal, H.7
  • 5
    • 0034600355 scopus 로고    scopus 로고
    • Papillomaviruses causing cancer: Evasion from host-cell control in early events in carcinogenesis
    • zur Hausen H. Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst 2000;92:690-8.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 690-698
    • Zur Hausen, H.1
  • 6
    • 0035956215 scopus 로고    scopus 로고
    • The Human Papillomavirus E6 protein and its contribution to malignant progression
    • DOI 10.1038/sj/onc/1204869
    • Mantovani F, Banks L. The human papillomavirus E6 protein and its contribution to malignant progression. Oncogene 2001;20: 7874-87. (Pubitemid 33135314)
    • (2001) Oncogene , vol.20 , Issue.54 REV. ISS. 7 , pp. 7874-7887
    • Mantovani, F.1    Banks, L.2
  • 7
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • DOI 10.1016/S0168-1702(02)00190-9, PII S0168170202001909
    • Munger K, Howley PM. Human papillomavirus immortalization and transformation functions. Virus Res 2002;89:213-28. (Pubitemid 35351540)
    • (2002) Virus Research , vol.89 , Issue.2 , pp. 213-228
    • Munger, K.1    Howley, P.M.2
  • 8
    • 0034730196 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle
    • Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S, Gonzalez S, Crum CP, Munger K. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc Natl Acad Sci USA 2000;97: 10002-7.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10002-10007
    • Duensing, S.1    Lee, L.Y.2    Duensing, A.3    Basile, J.4    Piboonniyom, S.5    Gonzalez, S.6    Crum, C.P.7    Munger, K.8
  • 10
    • 33845905779 scopus 로고    scopus 로고
    • The natural history of cervical HPV infection: Unresolved issues
    • DOI 10.1038/nrc2050, PII NRC2050
    • Woodman CB, Collins SI, Young LS. The natural history of cervical HPV infection: unresolved issues. Nat Rev Cancer 2007;7:11-22. (Pubitemid 46020844)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.1 , pp. 11-22
    • Woodman, C.B.J.1    Collins, S.I.2    Young, L.S.3
  • 11
    • 2542550364 scopus 로고    scopus 로고
    • Systematic review of genomic integration sites of human papillomavirus genomes in epithelial dysplasia and invasive cancer of the female lower genital tract
    • DOI 10.1158/0008-5472.CAN-04-0009
    • Wentzensen N, Vinokurova S, von Knebel Doeberitz M. Systematic review of genomic integration sites of human papillomavirus genomes in epithelial dysplasia and invasive cancer of the female lower genital tract. Cancer Res 2004;64:3878-84. (Pubitemid 38697299)
    • (2004) Cancer Research , vol.64 , Issue.11 , pp. 3878-3884
    • Wentzensen, N.1    Vinokurova, S.2    Von Knebel, D.M.3
  • 13
    • 33845308208 scopus 로고    scopus 로고
    • Detection of human papillomavirus type 16 integration in pre-neoplastic cervical lesions and confirmation by DIPS-PCR and sequencing
    • DOI 10.1016/j.jcv.2006.09.008, PII S1386653206003441
    • De Marco L, Gillio-Tos A, Bonello L, Ghisetti V, Ronco G, Merletti F. Detection of human papillomavirus type 16 integration in preneoplastic cervical lesions and confirmation by DIPS-PCR and sequencing. J Clin Virol 2007;38: 7-13. (Pubitemid 44881419)
    • (2007) Journal of Clinical Virology , vol.38 , Issue.1 , pp. 7-13
    • De Marco, L.1    Gillio-Tos, A.2    Bonello, L.3    Ghisetti, V.4    Ronco, G.5    Merletti, F.6
  • 14
    • 0033572319 scopus 로고    scopus 로고
    • Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes
    • Klaes R, Woerner SM, Ridder R, Wentzensen N, Duerst M, Schneider A, Lotz B, Melsheimer P, von Knebel Doeberitz M. Detection of high-risk cervical intraepithelial neoplasia and cervical cancer by amplification of transcripts derived from integrated papillomavirus oncogenes. Cancer Res 1999;59:6132-6. (Pubitemid 30035633)
    • (1999) Cancer Research , vol.59 , Issue.24 , pp. 6132-6136
    • Klaes, R.1    Woerner, S.M.2    Ridder, R.3    Wentzensen, N.4    Duerst, M.5    Schneider, A.6    Lotz, B.7    Melsheimer, P.8    Von Knebel, D.M.9
  • 15
    • 0035313988 scopus 로고    scopus 로고
    • Detection of integrated papillomavirus sequences by ligation-mediated pcr (DIPS-PCR) and molecular characterization in cervical cancer cells
    • Luft F, Klaes R, Nees M, Durst M, Heilmann V, Melsheimer P, von Knebel Doeberitz M. Detection of integrated papillomavirus sequences by ligation-mediated PCR (DIPS-PCR) and molecular characterization in cervical cancer cells. Int J Cancer 2001;92:9-17. (Pubitemid 32187026)
    • (2001) International Journal of Cancer , vol.92 , Issue.1 , pp. 9-17
    • Luft, F.1    Klaes, R.2    Nees, M.3    Durst, M.4    Heilmann, V.5    Melsheimer, P.6    Von Doeberitz, M.K.7
  • 16
    • 0036196505 scopus 로고    scopus 로고
    • Integrated human papillomavirus type 16 is frequently found in cervical cancer precursors as demonstrated by a novel quantitative real-time PCR technique
    • DOI 10.1128/JCM.40.3.886-891.2002
    • Peitsaro P, Johansson B, Syrjanen S. Integrated human papillomavirus type 16 is frequently found in cervical cancer precursors as demonstrated by a novel quantitative real-time PCR technique. J Clin Microbiol 2002;40:886-91. (Pubitemid 34208640)
    • (2002) Journal of Clinical Microbiology , vol.40 , Issue.3 , pp. 886-891
    • Peitsaro, P.1    Johansson, B.2    Syrjanen, S.3
  • 17
    • 1242319406 scopus 로고    scopus 로고
    • Mechanisms of genomic instability in human cancer: Insights from studies with human papillomavirus oncoproteins
    • DOI 10.1002/ijc.11691
    • Duensing S, Munger K. Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. Int J Cancer 2004;109:157-62. (Pubitemid 38240914)
    • (2004) International Journal of Cancer , vol.109 , Issue.2 , pp. 157-162
    • Duensing, S.1    Munger, K.2
  • 18
    • 1242316161 scopus 로고    scopus 로고
    • Acquisition of High-Level Chromosomal Instability Is Associated with Integration of Human Papillomavirus Type 16 in Cervical Keratinocytes
    • DOI 10.1158/0008-5472.CAN-03-3214
    • Pett MR, Alazawi WO, Roberts I, Dowen S, Smith DI, Stanley MA, Coleman N. Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes. Cancer Res 2004;64:1359-68. (Pubitemid 38235604)
    • (2004) Cancer Research , vol.64 , Issue.4 , pp. 1359-1368
    • Pett, M.R.1    Alazawi, W.O.F.2    Roberts, I.3    Dowen, S.4    Smith, D.I.5    Stanley, M.A.6    Coleman, N.7
  • 19
    • 2442602302 scopus 로고    scopus 로고
    • DNA Aneuploidy and Integration of Human Papillomavirus Type 16 E6/E7 Oncogenes in Intraepithelial Neoplasia and Invasive Squamous Cell Carcinoma of the Cervix Uteri
    • DOI 10.1158/1078-0432.CCR-03-0565
    • Melsheimer P, Vinokurova S, Wentzensen N, Bastert G, von Knebel Doeberitz M. DNA aneuploidy and integration of human papillomavirus type 16 e6/e7 oncogenes in intraepithelial neoplasia and invasive squamous cell carcinoma of the cervix uteri. Clin Cancer Res 2004;10:3059-63. (Pubitemid 38619683)
    • (2004) Clinical Cancer Research , vol.10 , Issue.9 , pp. 3059-3063
    • Melsheimer, P.1    Vinokurova, S.2    Wentzensen, N.3    Bastert, G.4    Von Knebel, D.M.5
  • 20
    • 40449129515 scopus 로고    scopus 로고
    • Integration of the HPV16 genome does not invariably result in high levels of viral oncogene transcripts
    • DOI 10.1038/sj.onc.1210791, PII 1210791
    • Hafner N, Driesch C, Gajda M, Jansen L, Kirchmayr R, Runnebaum IB, Durst M. Integration of the HPV16 genome does not invariably result in high levels of viral oncogene transcripts. Oncogene 2008;27:1610-7. (Pubitemid 351347875)
    • (2008) Oncogene , vol.27 , Issue.11 , pp. 1610-1617
    • Hafner, N.1    Driesch, C.2    Gajda, M.3    Jansen, L.4    Kirchmayr, R.5    Runnebaum, I.B.6    Durst, M.7
  • 22
    • 66349112294 scopus 로고    scopus 로고
    • Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses
    • Kadaja M, Isok-Paas H, Laos T, Ustav E, Ustav M. Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses. PLoS Pathog 2009;5:e1000397.
    • (2009) PLoS Pathog , vol.5
    • Kadaja, M.1    Isok-Paas, H.2    Laos, T.3    Ustav, E.4    Ustav, M.5
  • 25
    • 77951156890 scopus 로고    scopus 로고
    • Prognostic significance of HPV physical status and integration sites in cervical cancer
    • Nambaru L, Meenakumari B, Swaminathan R, Rajkumar T. Prognostic significance of HPV physical status and integration sites in cervical cancer. Asian Pac J Cancer Prev 2009;10:355-60.
    • (2009) Asian Pac J Cancer Prev , vol.10 , pp. 355-360
    • Nambaru, L.1    Meenakumari, B.2    Swaminathan, R.3    Rajkumar, T.4
  • 26
    • 62549166628 scopus 로고    scopus 로고
    • Identification of human papillomavirus type 16 integration sites in high-grade precancerous cervical lesions
    • Matovina M, Sabol I, Grubisic G, Gasperov NM, Grce M. Identification of human papillomavirus type 16 integration sites in high-grade precancerous cervical lesions. Gynecol Oncol 2009;113:120-7.
    • (2009) Gynecol Oncol , vol.113 , pp. 120-127
    • Matovina, M.1    Sabol, I.2    Grubisic, G.3    Gasperov, N.M.4    Grce, M.5
  • 28
    • 0037468256 scopus 로고    scopus 로고
    • Common fragile sites are preferential targets for HPV16 integrations in cervical tumors
    • DOI 10.1038/sj.onc.1206170
    • Thorland EC, Myers SL, Gostout BS, Smith DI. Common fragile sites are preferential targets for HPV16 integrations in cervical tumors. Oncogene 2003;22:1225-37. (Pubitemid 36363386)
    • (2003) Oncogene , vol.22 , Issue.8 , pp. 1225-1237
    • Thorland, E.C.1    Myers, S.L.2    Gostout, B.S.3    Smith, D.I.4
  • 29
    • 0038677462 scopus 로고    scopus 로고
    • A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques
    • DOI 10.1038/sj.onc.1206629
    • Ziegert C, Wentzensen N, Vinokurova S, Kisseljov F, Einenkel J, Hoeckel M, von Knebel Doeberitz M. A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques. Oncogene 2003;22:3977-84. (Pubitemid 36819671)
    • (2003) Oncogene , vol.22 , Issue.25 , pp. 3977-3984
    • Ziegert, C.1    Wentzensen, N.2    Vinokurova, S.3    Kisseljov, F.4    Einenkel, J.5    Hoeckel, M.6    Von Knebel, D.M.7
  • 30
    • 42049098182 scopus 로고    scopus 로고
    • The majority of viral-cellular fusion transcripts in cervical carcinomas cotranscribe cellular sequences of known or predicted genes
    • DOI 10.1158/0008-5472.CAN-07-2776
    • Kraus I, Driesch C, Vinokurova S, Hovig E, Schneider A, von Knebel Doeberitz M, Durst M. The majority of viral-cellular fusion transcripts in cervical carcinomas cotranscribe cellular sequences of known or predicted genes. Cancer Res 2008;68:2514-22. (Pubitemid 351521828)
    • (2008) Cancer Research , vol.68 , Issue.7 , pp. 2514-2522
    • Kraus, I.1    Driesch, C.2    Vinokurova, S.3    Hovig, E.4    Schneider, A.5    Doeberitz, M.V.K.6    Durst, M.7
  • 34
    • 0032472376 scopus 로고    scopus 로고
    • APM-1, a novel human gene, identified by aberrant co-transcription with papillomavirus oncogenes in a cervical carcinoma cell line, encodes a BTB/POZ-zinc finger protein with growth inhibitory activity
    • DOI 10.1093/emboj/17.1.215
    • Reuter S, Bartelmann M, Vogt M, Geisen C, Napierski I, Kahn T, Delius H, Lichter P, Weitz S, Korn B, Schwarz E. APM-1, a novel human gene, identified by aberrant cotranscription with papillomavirus oncogenes in a cervical carcinoma cell line, encodes a BTB/POZ-zinc finger protein with growth inhibitory activity. EMBO J 1998;17:215-22. (Pubitemid 28041062)
    • (1998) EMBO Journal , vol.17 , Issue.1 , pp. 215-222
    • Reuter, S.1    Bartelmann, M.2    Vogt, M.3    Geisen, C.4    Napierski, I.5    Kahn, T.6    Delius, H.7    Lichter, P.8    Weitz, S.9    Korn, B.10    Schwarz, E.11
  • 35
    • 33646124020 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation
    • Liu Z, Yang X, Tan F, Cullion K, Thiele CJ. Molecular cloning and characterization of human Castor, a novel human gene upregulated during cell differentiation. Biochem Biophys Res Commun 2006;344:834-44.
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 834-844
    • Liu, Z.1    Yang, X.2    Tan, F.3    Cullion, K.4    Thiele, C.J.5
  • 36
    • 79954539319 scopus 로고    scopus 로고
    • CASZ1b, the short isoform of CASZ1 gene, coexpresses with CASZ1a during neurogenesis and suppresses neuroblastoma cell growth
    • Liu Z, Naranjo A, Thiele CJ. CASZ1b, the short isoform of CASZ1 gene, coexpresses with CASZ1a during neurogenesis and suppresses neuroblastoma cell growth. PLoS One 2011;6: e18557.
    • (2011) PLoS One , vol.6
    • Liu, Z.1    Naranjo, A.2    Thiele, C.J.3
  • 38
    • 0032190216 scopus 로고    scopus 로고
    • Endocrine tumors of the cervix: Morphologic assessment, expression of human papillomavirus, and evaluation for loss of heterozygosity on 1p, 3p, 11q, and 17p
    • DOI 10.1002/(SICI)1097-0142(19981001)83:7<1391::AID-CNCR17>3.0. CO;2-#
    • Mannion C, Park WS, Man YG, Zhuang Z, Albores-Saavedra J, Tavassoli FA. Endocrine tumors of the cervix: morphologic assessment, expression of human papillomavirus, and evaluation for loss of heterozygosity on 1p,3p, 11q, and 17p. Cancer 1998;83:1391-400. (Pubitemid 28460091)
    • (1998) Cancer , vol.83 , Issue.7 , pp. 1391-1400
    • Mannion, C.1    Park, W.-S.2    Man, Y.G.3    Zhuang, Z.4    Albores-Saavedra, J.5    Tavassoli, F.A.6
  • 39
    • 0344980366 scopus 로고    scopus 로고
    • Allelic loss on chromosome 1 is associated with tumor progression of cervical carcinoma
    • DOI 10.1002/(SICI)1097-0142(19991001)86:7<1294::AID-CNCR26>3.0. CO;2-O
    • Cheung TH, Chung TK, Poon CS, Hampton GM, Wang VW, Wong YF. Allelic loss on chromosome 1 is associated with tumor progression of cervical carcinoma. Cancer 1999; 86:1294-8. (Pubitemid 29447014)
    • (1999) Cancer , vol.86 , Issue.7 , pp. 1294-1298
    • Cheung, T.H.1    Chung, T.K.H.2    Poon, C.S.3    Hampton, G.M.4    Wang, V.W.5    Wong, Y.F.6
  • 41
    • 0026440781 scopus 로고
    • Castor encodes a novel zinc finger protein required for the development of a subset of CNS neurons in Drosophila
    • Mellerick DM, Kassis JA, Zhang SD, Odenwald WF. castor encodes a novel zinc finger protein required for the development of a subset of CNS neurons in Drosophila. Neuron 1992;9:789-803.
    • (1992) Neuron , vol.9 , pp. 789-803
    • Mellerick, D.M.1    Kassis, J.A.2    Zhang, S.D.3    Odenwald, W.F.4
  • 42
    • 0027099862 scopus 로고
    • Ming is expressed in neuroblast sublineages and regulates gene expression in the Drosophila central nervous system
    • Cui X, Doe CQ. ming is expressed in neuroblast sublineages and regulates gene expression in the Drosophila central nervous system. Development 1992;116:943-52. (Pubitemid 23042435)
    • (1992) Development , vol.116 , Issue.4 , pp. 943-952
    • Cui, X.1    Doe, C.Q.2
  • 44
    • 41649104495 scopus 로고    scopus 로고
    • Vertebrate CASTOR Is Required for Differentiation of Cardiac Precursor Cells at the Ventral Midline
    • DOI 10.1016/j.devcel.2008.01.009, PII S1534580708000373
    • Christine KS, Conlon FL. Vertebrate CASTOR is required for differentiation of cardiac precursor cells at the ventral midline. Dev Cell 2008;14: 616-23. (Pubitemid 351479934)
    • (2008) Developmental Cell , vol.14 , Issue.4 , pp. 616-623
    • Christine, K.S.1    Conlon, F.L.2


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