MC-002 exhibits positive effects against platelets aggregation and endothelial dysfunction through thromboxane A2 inhibition

Thrombosis Research

Volumn 133, Issue 4, 2014, Pages 610-615

  Fang, Weirong ^a   Wei, Jie ^a   Han, Dan ^a   Chen, Xi ^a   He, Guangwei ^b   Wu, Qiang ^b   Chu, Shaoxing ^b   Li, Yunman ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Hefei Yigong Medicine Co Ltd   (China)

Author keywords

Inflammation; MC 002; Platelet aggregation

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 3 [3 METHOXY 4 [(3,5,6 TRIMETHYLPYRAZIN 2 YL]METHOXY]PHENYL)SODIUM ACRYLATE; 6 OXOPROSTAGLANDIN F1 ALPHA; ANTITHROMBOCYTIC AGENT; CALCIUM; CELL ADHESION MOLECULE; ENDOTHELIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MC 002; NITRIC OXIDE; PADGEM PROTEIN; THROMBOXANE A2; THROMBOXANE B2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ACRYLIC ACID DERIVATIVE; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PYRAN DERIVATIVE; THROMBOXANE A2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MALE; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPECTROFLUOROMETRY; THORACIC AORTA; THROMBOCYTE AGGREGATION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR RING; VASOCONSTRICTION; VASODILATATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; RABBIT; RANDOMIZATION;

ACRYLATES; ANIMALS; HUMANS; MALE; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROSTAGLANDIN ANTAGONISTS; PYRANS; RABBITS; RANDOM ALLOCATION; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; THROMBOXANE A2;

EID: 84896120274     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2014.01.029     Document Type: Article

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