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Volumn 167, Issue 6, 2013, Pages 2449-2455

Novel oral anticoagulants in acute coronary syndrome

Author keywords

Acute coronary syndrome; Anticoagulants; Myocardial infarction; Platelet aggregation; Thrombin

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTIVITAMIN K; APIXABAN; ATOPAXAR; BLOOD CLOTTING FACTOR 10A INHIBITOR; CARBAMAZEPINE; CLOPIDOGREL; DABIGATRAN; DAREXABAN; FONDAPARINUX; HEPARIN; HIRULOG; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; HYPERICUM PERFORATUM EXTRACT; ITRACONAZOLE; KETOCONAZOLE; LOW MOLECULAR WEIGHT HEPARIN; PHENOBARBITAL; PHENYTOIN; PLACEBO; POSACONAZOLE; RIFAMPICIN; RIVAROXABAN; THROMBIN INHIBITOR; UNINDEXED DRUG; VORAPAXAR; VORICONAZOLE; WARFARIN; XIMELAGATRAN;

EID: 84883749171     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.08.014     Document Type: Review
Times cited : (35)

References (51)
  • 1
    • 81255167006 scopus 로고    scopus 로고
    • The year in non-ST-segment elevation acute coronary syndrome
    • R.P. Giugliano, and E. Braunwald The year in non-ST-segment elevation acute coronary syndrome J Am Coll Cardiol 58 2011 2342 2354
    • (2011) J Am Coll Cardiol , vol.58 , pp. 2342-2354
    • Giugliano, R.P.1    Braunwald, E.2
  • 2
    • 0028059056 scopus 로고
    • Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture
    • P.R. Moreno, E. Falk, I.F. Palacios, J.B. Newell, V. Fuster, and J.T. Fallon Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture Circulation 90 1994 775 778
    • (1994) Circulation , vol.90 , pp. 775-778
    • Moreno, P.R.1    Falk, E.2    Palacios, I.F.3    Newell, J.B.4    Fuster, V.5    Fallon, J.T.6
  • 3
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • R. Ross Atherosclerosis-an inflammatory disease N Engl J Med 34 1999 115 126
    • (1999) N Engl J Med , vol.34 , pp. 115-126
    • Ross, R.1
  • 4
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • S.R. Coughlin Thrombin signalling and protease-activated receptors Nature 407 2000 258 264
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 5
    • 60849087332 scopus 로고    scopus 로고
    • Protease-activated receptors as targets for antiplatelet therapy
    • J.R. Hamilton Protease-activated receptors as targets for antiplatelet therapy Blood Rev 23 2009 61 65
    • (2009) Blood Rev , vol.23 , pp. 61-65
    • Hamilton, J.R.1
  • 6
    • 50649123533 scopus 로고    scopus 로고
    • Time course of events in acute coronary syndromes: Implications for clinical practice from the GRACE registry
    • K.A. Fox, F.A. Anderson Jr., and S.G. Goodman Time course of events in acute coronary syndromes: Implications for clinical practice from the GRACE registry Nat Clin Pract Cardiovasc Med 5 2008 580 589
    • (2008) Nat Clin Pract Cardiovasc Med , vol.5 , pp. 580-589
    • Fox, K.A.1    Anderson, Jr.F.A.2    Goodman, S.G.3
  • 7
    • 0035899289 scopus 로고    scopus 로고
    • The Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • The Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation N Engl J Med 345 2001 494 502
    • (2001) N Engl J Med , vol.345 , pp. 494-502
  • 8
    • 84856158305 scopus 로고    scopus 로고
    • ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)
    • C.W. Hamm, J.P. Bassand, and S. Agewall ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC) Eur Heart J 32 2011 2999 3054
    • (2011) Eur Heart J , vol.32 , pp. 2999-3054
    • Hamm, C.W.1    Bassand, J.P.2    Agewall, S.3
  • 9
    • 0000189825 scopus 로고    scopus 로고
    • Low-molecular-weight heparin during instability in coronary artery disease, Fragmin during instability in coronary artery disease (FRISC) study group
    • Low-molecular-weight heparin during instability in coronary artery disease, Fragmin during instability in coronary artery disease (FRISC) study group Lancet 347 1996 561 568
    • (1996) Lancet , vol.347 , pp. 561-568
  • 11
    • 71749087343 scopus 로고    scopus 로고
    • Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: A retrospective analysis of nationwide registry data
    • R. Sørensen, M.L. Hansen, and S.Z. Abildstrom Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data Lancet 374 2009 1967 1974
    • (2009) Lancet , vol.374 , pp. 1967-1974
    • Sørensen, R.1    Hansen, M.L.2    Abildstrom, S.Z.3
  • 12
    • 0026432629 scopus 로고
    • Oral anticoagulant drugs
    • J. Hirsh Oral anticoagulant drugs N Engl J Med 324 1991 1865 1875
    • (1991) N Engl J Med , vol.324 , pp. 1865-1875
    • Hirsh, J.1
  • 13
    • 4644230820 scopus 로고    scopus 로고
    • The pharmacology and management of the vitamin K antagonists: The seventh ACCP conference on antithrombotic and thrombolytic therapy
    • J. Ansell, J. Hirsh, L. Poller, H. Bussey, A. Jacobson, and E. Hylek The pharmacology and management of the vitamin K antagonists: the seventh ACCP conference on antithrombotic and thrombolytic therapy Chest 126 2004 204S 233S
    • (2004) Chest , vol.126
    • Ansell, J.1    Hirsh, J.2    Poller, L.3    Bussey, H.4    Jacobson, A.5    Hylek, E.6
  • 14
    • 0041829444 scopus 로고    scopus 로고
    • Oral ximelagatran for secondary prophylaxis after myocardial infarction: The ESTEEM randomised controlled trial
    • L. Wallentin, R.G. Wilcox, and W.D. Weaver Oral ximelagatran for secondary prophylaxis after myocardial infarction: the ESTEEM randomised controlled trial Lancet 362 2003 789 797
    • (2003) Lancet , vol.362 , pp. 789-797
    • Wallentin, L.1    Wilcox, R.G.2    Weaver, W.D.3
  • 16
    • 80052825103 scopus 로고    scopus 로고
    • Apixaban versus warfarin in patients with atrial fibrillation
    • C.B. Granger, J.H. Alexander, and J.J. McMurray Apixaban versus warfarin in patients with atrial fibrillation NEJM 365 2011 981 992
    • (2011) NEJM , vol.365 , pp. 981-992
    • Granger, C.B.1    Alexander, J.H.2    McMurray, J.J.3
  • 17
    • 77953661122 scopus 로고    scopus 로고
    • LB-MO-005 Late breaking clinical trial: The ADVANCE - 2 study: A randomized double-blind trial comparing apixaban with enoxaparin for thromboprophylaxis after total knee replacement
    • [Boston, MA.]
    • M.R. Lassen, A.S. Gallus, G.F. Pineo, and G.E. Raskob LB-MO-005 Late breaking clinical trial: The ADVANCE - 2 study: A randomized double-blind trial comparing apixaban with enoxaparin for thromboprophylaxis after total knee replacement Presented at XXII Congress of the International Society on Thrombosis and Hemostasis July 11-16 2009 [Boston, MA.]
    • (2009) Presented at XXII Congress of the International Society on Thrombosis and Hemostasis , vol.11
    • Lassen, M.R.1    Gallus, A.S.2    Pineo, G.F.3    Raskob, G.E.4
  • 18
    • 67649563209 scopus 로고    scopus 로고
    • Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: Results of the apixaban for prevention of acute ischemic and safety events (APPRAISE) trial
    • J.H. Alexander, R.C. Becker, and D.L. Bhatt Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: results of the apixaban for prevention of acute ischemic and safety events (APPRAISE) trial Circulation 119 2009 2877 2885
    • (2009) Circulation , vol.119 , pp. 2877-2885
    • Alexander, J.H.1    Becker, R.C.2    Bhatt, D.L.3
  • 19
    • 23044505564 scopus 로고    scopus 로고
    • Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients
    • S. Schulman, and C. Kearon Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients J Thromb Haemost 3 2005 692 694
    • (2005) J Thromb Haemost , vol.3 , pp. 692-694
    • Schulman, S.1    Kearon, C.2
  • 20
    • 80052162121 scopus 로고    scopus 로고
    • APPRAISE-2 Investigators. Apixaban with antiplatelet therapy after acute coronary syndrome
    • J.H. Alexander, R.D. Lopes, and S. James APPRAISE-2 Investigators. Apixaban with antiplatelet therapy after acute coronary syndrome NEJM 365 2011 699 708
    • (2011) NEJM , vol.365 , pp. 699-708
    • Alexander, J.H.1    Lopes, R.D.2    James, S.3
  • 22
    • 78650619315 scopus 로고    scopus 로고
    • Oral rivaroxaban for symptomatic venous thromboembolism
    • R. Bauersachs, S.D. Berkowitz, and B. Brenner Oral rivaroxaban for symptomatic venous thromboembolism N Engl J Med 363 2010 2499 2510
    • (2010) N Engl J Med , vol.363 , pp. 2499-2510
    • Bauersachs, R.1    Berkowitz, S.D.2    Brenner, B.3
  • 23
    • 77952037752 scopus 로고    scopus 로고
    • Rivaroxaban: A Direct Factor Xa Inhibitor for VTE Prophylaxis in Patients Undergoing Total Knee or Hip Replacement Surgery
    • H. Wong, N. Nunokawa, and J.C. Song 'Rivaroxaban: A Direct Factor Xa Inhibitor for VTE Prophylaxis in Patients Undergoing Total Knee or Hip Replacement Surgery.' Formulary 44 2009 226 236
    • (2009) Formulary , vol.44 , pp. 226-236
    • Wong, H.1    Nunokawa, N.2    Song, J.C.3
  • 24
    • 80052592404 scopus 로고    scopus 로고
    • Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
    • M.R. Patel, K.W. Mahaffey, and J. Garg Rivaroxaban versus warfarin in nonvalvular atrial fibrillation NEJM 365 2011 883 891
    • (2011) NEJM , vol.365 , pp. 883-891
    • Patel, M.R.1    Mahaffey, K.W.2    Garg, J.3
  • 25
    • 67649562905 scopus 로고    scopus 로고
    • Rivaroxaban versus placebo in patients with acute coronary syndromes (Atlas Acs-Timi 46): A randomised, double-blind, phase II trial
    • J.L. Mega, E. Braunwald, and S. Mohanavelu Rivaroxaban versus placebo in patients with acute coronary syndromes (Atlas Acs-Timi 46): a randomised, double-blind, phase II trial Lancet 374 2009 29 38
    • (2009) Lancet , vol.374 , pp. 29-38
    • Mega, J.L.1    Braunwald, E.2    Mohanavelu, S.3
  • 26
    • 84862907587 scopus 로고    scopus 로고
    • ATLAS ACS 2-TIMI 51 Investigators. Rivaroxaban in patients with a recent acute coronary syndrome
    • J.L. Mega, E. Braunwald, and S.D. Wiviott ATLAS ACS 2-TIMI 51 Investigators. Rivaroxaban in patients with a recent acute coronary syndrome NEJM 366 2012 9 19
    • (2012) NEJM , vol.366 , pp. 9-19
    • Mega, J.L.1    Braunwald, E.2    Wiviott, S.D.3
  • 27
    • 80054759751 scopus 로고    scopus 로고
    • Co-administration of darexaban (YM150), an oral direct factor Xa inhibitor, with acetylsalicylic acid, clopidogrel and naproxen: No evidence of clinically relevant interactions
    • M. Heeringa, D. Groenendaal, and G. Strabach Co-administration of darexaban (YM150), an oral direct factor Xa inhibitor, with acetylsalicylic acid, clopidogrel and naproxen: no evidence of clinically relevant interactions J Thromb Hemost 9 Suppl. 2 2007 360
    • (2007) J Thromb Hemost , vol.9 , Issue.SUPPL. 2 , pp. 360
    • Heeringa, M.1    Groenendaal, D.2    Strabach, G.3
  • 28
    • 80054738278 scopus 로고    scopus 로고
    • The pharmacokinetics of YM150, an oral direct factor Xa inhibitor, are not affected to a clinically relevant degree by strong inhibition or induction of CYP3A4 and P-gp
    • M. Heeringa, D. Groenendaal, and G. Strabach The pharmacokinetics of YM150, an oral direct factor Xa inhibitor, are not affected to a clinically relevant degree by strong inhibition or induction of CYP3A4 and P-gp J Thromb Hemost 9 Suppl. 2 2011 359 360
    • (2011) J Thromb Hemost , vol.9 , Issue.SUPPL. 2 , pp. 359-360
    • Heeringa, M.1    Groenendaal, D.2    Strabach, G.3
  • 29
    • 77649141852 scopus 로고    scopus 로고
    • ONYX-2 STUDY GROUP. Prevention of venous thromboembolism with an oral factor Xa inhibitor, YM150, after total hip arthroplasty. A dose finding study (ONYX-2)
    • B.I. Eriksson, A.G.G. Turpie, and M.R. Lassen ONYX-2 STUDY GROUP. Prevention of venous thromboembolism with an oral factor Xa inhibitor, YM150, after total hip arthroplasty. A dose finding study (ONYX-2) J Thromb Haemost 8 2010 714 721
    • (2010) J Thromb Haemost , vol.8 , pp. 714-721
    • Eriksson, B.I.1    Turpie, A.G.G.2    Lassen, M.R.3
  • 31
    • 80054733922 scopus 로고    scopus 로고
    • RUBY-1 Investigators. RUBY-1: A randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome
    • P.G. Steg, S.R. Mehta, and J.W. Jukema RUBY-1 Investigators. RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome Eur Heart J 32 2011 2541 2554
    • (2011) Eur Heart J , vol.32 , pp. 2541-2554
    • Steg, P.G.1    Mehta, S.R.2    Jukema, J.W.3
  • 32
    • 34548031359 scopus 로고    scopus 로고
    • The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
    • J. Stangier, K. Rathgen, H. Stahle, D. Gansser, and W. Roth The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects Br J Clin Pharmacol 64 2007 292 303
    • (2007) Br J Clin Pharmacol , vol.64 , pp. 292-303
    • Stangier, J.1    Rathgen, K.2    Stahle, H.3    Gansser, D.4    Roth, W.5
  • 34
    • 78650034786 scopus 로고    scopus 로고
    • Novel anticoagulants for stroke prevention in atrial fibrillation: Current clinical evidence and future developments
    • S.H. Schirmer, M. Baumhakel, and H.R. Neuberger Novel anticoagulants for stroke prevention in atrial fibrillation: current clinical evidence and future developments J Am Coll Cardiol 56 2010 2067 2076
    • (2010) J Am Coll Cardiol , vol.56 , pp. 2067-2076
    • Schirmer, S.H.1    Baumhakel, M.2    Neuberger, H.R.3
  • 35
    • 71849117615 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in the treatment of acute venous thromboembolism
    • S. Schulman, C. Kearon, and A.K. Kakkar Dabigatran versus warfarin in the treatment of acute venous thromboembolism NEMJ 361 2009 2342 2352
    • (2009) NEMJ , vol.361 , pp. 2342-2352
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 36
    • 77956977472 scopus 로고    scopus 로고
    • Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: An analysis of the Re-Ly trial
    • L. Wallentin, S. Yusuf, and M.D. Ezekowitz Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the Re-Ly trial Lancet 376 2010 975 983
    • (2010) Lancet , vol.376 , pp. 975-983
    • Wallentin, L.1    Yusuf, S.2    Ezekowitz, M.D.3
  • 37
    • 80052232522 scopus 로고    scopus 로고
    • RE-DEEM Investigators. Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: A randomized, double-blind, phase II trial
    • J. Oldgren, A. Budaj, and C.B. Granger RE-DEEM Investigators. Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial Eur Heart J 32 2011 2781 2789
    • (2011) Eur Heart J , vol.32 , pp. 2781-2789
    • Oldgren, J.1    Budaj, A.2    Granger, C.B.3
  • 38
    • 33947316375 scopus 로고    scopus 로고
    • Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischaemic events: Observations from the ESTEEM Trial
    • C. Christersson, J. Oldgren, A. Bylock, A. Siegbahn, and L. Wallentin Early decrease in coagulation activity after myocardial infarction is associated with lower risk of new ischaemic events: observations from the ESTEEM Trial Eur Heart J 28 2007 692 698
    • (2007) Eur Heart J , vol.28 , pp. 692-698
    • Christersson, C.1    Oldgren, J.2    Bylock, A.3    Siegbahn, A.4    Wallentin, L.5
  • 39
    • 76549094772 scopus 로고    scopus 로고
    • Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases
    • J.M. Siller-Matula, J. Krumphuber, and B. Jilma Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases Br J Pharmacol 15 2010 502 517
    • (2010) Br J Pharmacol , vol.15 , pp. 502-517
    • Siller-Matula, J.M.1    Krumphuber, J.2    Jilma, B.3
  • 40
    • 61849180442 scopus 로고    scopus 로고
    • TRA-PCI Investigators. Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: A randomised, double-blind, placebo-controlled phase II study
    • R.C. Becker, D.J. Moliterno, and L.K. Jennings TRA-PCI Investigators. Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study Lancet 373 2009 919 928
    • (2009) Lancet , vol.373 , pp. 919-928
    • Becker, R.C.1    Moliterno, D.J.2    Jennings, L.K.3
  • 41
    • 77649207578 scopus 로고    scopus 로고
    • Safety and exploratory efficacy of the novel thrombin receptor (PAR-1) antagonist SCH530348 for non-ST-segment elevation acute coronary syndrome
    • S. Goto, T. Yamaguchi, Y. Ikeda, K. Kato, H. Yamaguchi, and P. Jensen Safety and exploratory efficacy of the novel thrombin receptor (PAR-1) antagonist SCH530348 for non-ST-segment elevation acute coronary syndrome J Atheroscler Thromb 17 2010 156 164
    • (2010) J Atheroscler Thromb , vol.17 , pp. 156-164
    • Goto, S.1    Yamaguchi, T.2    Ikeda, Y.3    Kato, K.4    Yamaguchi, H.5    Jensen, P.6
  • 42
    • 83655177669 scopus 로고    scopus 로고
    • TRACER Investigators. Thrombin-receptor antagonist vorapaxar in acute coronary syndromes
    • P. Tricoci, Z. Huang, and C. Held TRACER Investigators. Thrombin-receptor antagonist vorapaxar in acute coronary syndromes NEMJ 366 2012 20 33
    • (2012) NEMJ , vol.366 , pp. 20-33
    • Tricoci, P.1    Huang, Z.2    Held, C.3
  • 43
    • 85027946204 scopus 로고    scopus 로고
    • LANCELOT-ACS Investigators. Safety and tolerability of atopaxar in the treatment of patients with acute coronary syndromes: The lessons from antagonizing the cellular effects of Thrombin-Acute Coronary Syndromes Trial
    • M.L. O'Donoghue, D.L. Bhatt, and S.D. Wiviott LANCELOT-ACS Investigators. Safety and tolerability of atopaxar in the treatment of patients with acute coronary syndromes: the lessons from antagonizing the cellular effects of Thrombin-Acute Coronary Syndromes Trial Circulation 123 2011 1843 1853
    • (2011) Circulation , vol.123 , pp. 1843-1853
    • O'Donoghue, M.L.1    Bhatt, D.L.2    Wiviott, S.D.3
  • 44
    • 78149355554 scopus 로고    scopus 로고
    • J-LANCELOT (Japanese-Lesson from Antagonizing the Cellular Effect of Thrombin) Investigators. Double-blind, placebo-controlled Phase II studies of the protease-activated receptor 1 antagonist E5555 (atopaxar) in Japanese patients with acute coronary syndrome or high-risk coronary artery disease
    • S. Goto, H. Ogawa, M. Takeuchi, M.D. Flather, and D.L. Bhatt J-LANCELOT (Japanese-Lesson from Antagonizing the Cellular Effect of Thrombin) Investigators. Double-blind, placebo-controlled Phase II studies of the protease-activated receptor 1 antagonist E5555 (atopaxar) in Japanese patients with acute coronary syndrome or high-risk coronary artery disease Eur Heart J 31 2010 2601 2613
    • (2010) Eur Heart J , vol.31 , pp. 2601-2613
    • Goto, S.1    Ogawa, H.2    Takeuchi, M.3    Flather, M.D.4    Bhatt, D.L.5
  • 45
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: A randomized, placebo-controlled, crossover study in healthy subjects
    • E.S. Eerenberg, P.W. Kamphuisen, M.K. Sijpkens, J.C. Meijers, H.R. Buller, and M. Levi Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects Circulation 124 2011 1573 1579
    • (2011) Circulation , vol.124 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3    Meijers, J.C.4    Buller, H.R.5    Levi, M.6
  • 46
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate - A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • J. van Ryn, J. Stangier, and S. Haertter Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity Thromb Haemost 103 2010 1116 1127
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • Van Ryn, J.1    Stangier, J.2    Haertter, S.3
  • 48
    • 78649736882 scopus 로고    scopus 로고
    • Clinical laboratory measurement of direct factor Xa inhibitors: Anti-Xa assay is preferable to prothrombin time assay
    • Y.C. Barrett, Z. Wang, C. Frost, and A. Shenker Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay Thromb Haemost 104 2010 1263 1267
    • (2010) Thromb Haemost , vol.104 , pp. 1263-1267
    • Barrett, Y.C.1    Wang, Z.2    Frost, C.3    Shenker, A.4
  • 49
    • 84859800192 scopus 로고    scopus 로고
    • Clinical pharmacology basis of deriving dosing recommendations for dabigatran in patients with severe renal impairment
    • S. Hariharan, and R. Madabushi Clinical pharmacology basis of deriving dosing recommendations for dabigatran in patients with severe renal impairment J Clin Pharmacol 52 2012 119S 125S
    • (2012) J Clin Pharmacol , vol.52
    • Hariharan, S.1    Madabushi, R.2
  • 50
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • S. Wiviott, E. Braunwald, and C. McCabe Prasugrel versus clopidogrel in patients with acute coronary syndromes NEMJ 357 2007 2001 2015
    • (2007) NEMJ , vol.357 , pp. 2001-2015
    • Wiviott, S.1    Braunwald, E.2    McCabe, C.3
  • 51
    • 70149101223 scopus 로고    scopus 로고
    • For the PLATO Investigators. Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • L. Wallentin, R.C. Becker, and A. Budaj for the PLATO Investigators. Ticagrelor versus clopidogrel in patients with acute coronary syndromes NEMJ 361 2009 1045 1057
    • (2009) NEMJ , vol.361 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3


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