Absence of cardiovascular manifestations in a haploinsufficient Tgfbr1 mouse model

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Renard, Marjolijn ^a   Trachet, Bram ^b   Casteleyn, Christophe ^b,c   Campens, Laurence ^a   Cornillie, Pieter ^b   Callewaert, Bert ^a   Deleye, Steven ^b,c   Vandeghinste, Bert ^b   Van Heijningen, Paula M ^d   Dietz, Harry ^e   De Vos, Filip ^b   Essers, Jeroen ^d   Staelens, Steven ^b,c   Segers, Patrick ^b   Loeys, Bart ^a,f   Coucke, Paul ^a   De Paepe, Anne ^a   De Backer, Julie ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; PROTEIN SERINE THREONINE KINASE; STOP CODON; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA WALL; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; HAPLOINSUFFICIENCY; HETEROZYGOSITY; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MOUSE MUTANT; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; NONSENSE MUTATION; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1 GENE; VASCULARIZATION; WILD TYPE; ANIMAL; CARDIOVASCULAR MALFORMATION; DEFICIENCY; DISEASE MODEL; ECHOCARDIOGRAPHY; FLUORESCENCE; GENETICS; GENOTYPE; LOEYS DIETZ SYNDROME; MICRO-COMPUTED TOMOGRAPHY; NONPARAMETRIC TEST; PATHOPHYSIOLOGY; PHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; STOP CODON;

ANIMALS; CARDIOVASCULAR ABNORMALITIES; CODON, NONSENSE; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; FLUORESCENCE; GENOTYPE; HAPLOINSUFFICIENCY; IMMUNOHISTOCHEMISTRY; LOEYS-DIETZ SYNDROME; MICE; POSITRON-EMISSION TOMOGRAPHY; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; STATISTICS, NONPARAMETRIC; X-RAY MICROTOMOGRAPHY;

EID: 84896082253     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089749     Document Type: Article

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