T cell receptor signaling can directly enhance the avidity of CD28 ligand binding

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Sanchez Lockhart, Mariano ^a,d   Rojas, Ana V ^b   Fettis, Margaret M ^a   Bauserman, Richard ^c   Higa, Trissha R ^a   Miao, Hongyu ^b   Waugh, Richard E ^c   Miller, Jim ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

^c University of Rochester   (United States)

^d UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; HOMODIMER; T LYMPHOCYTE RECEPTOR; B7 ANTIGEN; HYBRID PROTEIN; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; IN VITRO STUDY; LIGAND BINDING; MICROPIPETTE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MUTAGENESIS; MUTATIONAL ANALYSIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; MUTATION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD28; ANTIGENS, CD80; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; MOLECULAR DYNAMICS SIMULATION; MUTATION; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84896076324     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089263     Document Type: Article

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