Evaluation of single-cell biomechanics as potential marker for oral squamous cell carcinomas: A pilot study

Oral Diseases

Volumn 20, Issue 3, 2014, Pages

  Runge, J ^a   Reichert, T E ^b   Fritsch, A ^a   Kas J ^a   Bertolini, J ^a   Remmerbach, T W ^a,c  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c GRIFFITH UNIVERSITY   (Australia)

Author keywords

Early cancer detection; Optical stretcher; Oral cancer; OSCC

Indexed keywords

BIOLOGICAL MARKER;

ARTICLE; BIOMECHANICS; CANCER CELL CULTURE; CARCINOMA CELL; CELL GROWTH; CONTROLLED STUDY; CYTOSKELETON; EARLY CANCER; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LASER; LIGHT EXPOSURE; MAJOR CLINICAL STUDY; MALE; MICROFLUIDICS; MOUTH CANCER; MOUTH SQUAMOUS CELL CARCINOMA; OPTICAL STRETCHER; PILOT STUDY; PRIMARY TUMOR; PRIORITY JOURNAL; SINGLE CELL ANALYSIS; SURFACE STRESS; TUMOR GROWTH; VISCOELASTICITY; ADULT; AGED; CYTOLOGY; MIDDLE AGED; MOUTH TUMOR; PATHOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL CULTURE;

ADULT; AGED; BIOMECHANICAL PHENOMENA; CARCINOMA, SQUAMOUS CELL; CYTOLOGICAL TECHNIQUES; HUMANS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; PILOT PROJECTS; TUMOR CELLS, CULTURED;

EID: 84896072377     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/odi.12171     Document Type: Article

References (25)

1. Clauß G, Finze FR, Partzsch L (2004). Statistik für Soziologen, Pädagogen, Psychologen und Mediziner: Grundlagen, Vol. 5. Verlag Harri Deutsch: Frankfurt am Main.
2. Dickson MA, Hahn WC, Ino Y et al (2000). Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol 20: 1436-1447.
3. Discher DE, Janmey P, Wang YL (2005). Tissue cells feel and respond to the stiffness of their substrate. Science 310: 1139-1143.
4. Elson EL (1988). Cellular mechanics as an indicator of cytoskeletal structure and function. Annu Rev Biophys Biophys Chem 17: 397-430.
5. Fritsch A, Höckel M, Kiessling T et al (2010). Are biomechanical changes necessary for tumour progression? Nat Phys 6: 730-732.
6. Gioanni J, Fischel JL, Lambert JC et al (1988). Two new human tumor cell lines derived from squamous cell carcinomas of the tongue: establishment, characterization and response to cytotoxic treatment. Eur J Cancer Clin Oncol 24: 1445-1455.
7. Greenlee R, Murray T, Bolden S, Wingo PA (2000). Cancer statistics, 2000. CA Cancer J Clin 50: 57-33.
8. Guck J, Ananthakrishnan R, Moon TJ, Cunningham CC, Käs J (2000). Optical deformability of soft biological dielectrics. Phys Rev Lett 84: 5451-5454.
9. Guck J, Ananthakrishnan R, Mahmood H, Moon TJ, Cunningham CC, Käs J (2001). The optical stretcher: a novel laser tool to micromanipulate cells. Biophys J 81: 767-784.
10. Guck J, Schinkinger S, Lincoln B et al (2005). Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence. Biophys J 88: 3689-3698.
11. Heo DS, Snyderman C, Gollin SM et al (1989). Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines. Cancer Res 49: 5167-5175.
12. Howlader N, Noone A, Krapcho M, Neyman N, Aminou R, Waldron W (2011). SEER Cancer Statistics Review, 1975-2008.
13. Katsantonis J, Tosca A, Koukouritaki SB, Theodoropoulos PA, Gravanis A, Stournaras C (1994). Differences in the G/total actin ratio and microfilament stability between normal and malignant human keratinocytes. Cell Biochem Funct 12: 267-274.
14. Kitano H (2003). Cancer robustness: tumour tactics. Nature 426: 125.
15. Lindl TG, Gstraunthaler G (2008). Zell- und Gewebekultur, von den Grundlagen zur Laborbank, Vol. 6. Springer: Heidelberg.
16. Martin M, Müller K, Cadenas C et al (2012). ERBB2 overexpression triggers transient high mechanoactivity of breast tumor cells. Cytoskeleton (Hoboken) 69: 267-277.
17. Mehrotra R, Gupta A, Singh M, Ibrahim R (2006). Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. Mol Cancer 5: 11.
18. Müller-Richter UD, Dowejko A, Reuther T, Kleinheinz J, Reichert TE, Driemel O (2009). Analysis of expression profiles of MAGE-A antigens in oral squamous cell carcinoma cell lines. Head Face Med 5: 10.
19. Remmerbach T, Weidenbach H, Hemprich A, Boecking A (2003). Earliest detection of oral cancer using non-invasive brush biopsy including DNA-image-cytometry: report on four cases. Anal Cell Pathol 25: 159-166.
20. Remmerbach TW, Wottawah F, Dietrich J, Lincoln B, Wittekind C, Guck J (2009). Oral cancer diagnosis by mechanical phenotyping. Cancer Res 69: 1728-1732.
21. Rheinwald JG, Hahn WC, Ramsey MR et al (2002). A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol Cell Biol 22: 5157-5172.
22. Sacchi M, Snyderman CH, Heo DS et al (1990). Local adoptive immunotherapy of human head and neck cancer xenografts in nude mice with lymphokine-activated killer cells and interleukin 2. Cancer Res 50: 3113-3118.
23. Sciubba JJ (2001). Oral cancer. The importance of early diagnosis and treatment. Am J Clin Dermatol 2: 239-251.
24. Wittekind C, Meyer HJ, Bootz F (2005). TNM KLassifikation maligner Tumoren, Vol. 7. Springer: Berlin.
25. Wottawah F (2006). Optical cell rheology: from the microscopic origins of cellular elasticity to oral cancer diagnosis. Diss., University of Leipzig: Leipzig, p. 115.