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Volumn 67, Issue , 2014, Pages 57-64

Baicalein inhibits lipid accumulation by regulating early adipogenesis and m-TOR signaling

Author keywords

3T3 L1; Adipogenesis; M TOR signaling pathway; Mitotic clonal expansion; Triglyceride signaling pathway; Zebrafish

Indexed keywords

BAICALEIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN DELTA; CURCUMIN; KROX 20 PROTEIN; KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 5; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PREF 1 PROTEIN; S6 KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; FLAVANONE DERIVATIVE; MTOR PROTEIN, HUMAN; PRIMER DNA; TARGET OF RAPAMYCIN KINASE;

EID: 84896056661     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.02.009     Document Type: Article
Times cited : (44)

References (42)
  • 1
    • 66349115342 scopus 로고    scopus 로고
    • Adipocyte metabolism and obesity
    • Attie A.D., Scherer P.E. Adipocyte metabolism and obesity. J. Lipid Res. 2009, 50:S395-S399.
    • (2009) J. Lipid Res. , vol.50
    • Attie, A.D.1    Scherer, P.E.2
  • 3
    • 0034181368 scopus 로고    scopus 로고
    • Rapamycin inhibits human adipocyte differentiation in primary culture
    • Bell A., Grunder L., Sorisky A. Rapamycin inhibits human adipocyte differentiation in primary culture. Obesity Res. 2000, 8:249-254.
    • (2000) Obesity Res. , vol.8 , pp. 249-254
    • Bell, A.1    Grunder, L.2    Sorisky, A.3
  • 4
    • 41449116010 scopus 로고    scopus 로고
    • Transcriptional regulation of adipogenesis by KLF4
    • Birsoy K., Chen Z., Friedman J. Transcriptional regulation of adipogenesis by KLF4. Cell Metab. 2008, 7:339-347.
    • (2008) Cell Metab. , vol.7 , pp. 339-347
    • Birsoy, K.1    Chen, Z.2    Friedman, J.3
  • 5
    • 33745817850 scopus 로고    scopus 로고
    • Baicalein inhibits adipocyte differentiation by enhancing COX-2 expression
    • Cha M.H., Kim I.C., Lee B.H., Yoon Y. Baicalein inhibits adipocyte differentiation by enhancing COX-2 expression. J. Med. Food 2006, 9:145-153.
    • (2006) J. Med. Food , vol.9 , pp. 145-153
    • Cha, M.H.1    Kim, I.C.2    Lee, B.H.3    Yoon, Y.4
  • 6
    • 1042298763 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase expression by baicalein in endotoxin/cytokine-stimulated microglia
    • Chen C.J., Raung S.L., Liao S.L., Chen S.Y. Inhibition of inducible nitric oxide synthase expression by baicalein in endotoxin/cytokine-stimulated microglia. Biochem. Pharmacol. 2004, 67:957-965.
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 957-965
    • Chen, C.J.1    Raung, S.L.2    Liao, S.L.3    Chen, S.Y.4
  • 7
    • 24344507734 scopus 로고    scopus 로고
    • Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms
    • Chen Z., Torrens J.I., Anand A., Spiegelman B.M., Friedman J.M. Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. Cell Metab. 2005, 1:93-106.
    • (2005) Cell Metab. , vol.1 , pp. 93-106
    • Chen, Z.1    Torrens, J.I.2    Anand, A.3    Spiegelman, B.M.4    Friedman, J.M.5
  • 8
    • 80054057662 scopus 로고    scopus 로고
    • Mammalian triacylglycerol metabolism: synthesis, lipolysis and signaling
    • Coleman R.A., Mashek D.G. Mammalian triacylglycerol metabolism: synthesis, lipolysis and signaling. Chem. Rev. 2011, 111:6359-6386.
    • (2011) Chem. Rev. , vol.111 , pp. 6359-6386
    • Coleman, R.A.1    Mashek, D.G.2
  • 9
    • 0032515065 scopus 로고    scopus 로고
    • The role of C/EBP genes in adipocyte differentiation
    • Darlington G.J., Ross S.E., MacDougald O.A. The role of C/EBP genes in adipocyte differentiation. J. Biol. Chem. 1998, 273:30057-30060.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30057-30060
    • Darlington, G.J.1    Ross, S.E.2    MacDougald, O.A.3
  • 11
    • 0345732640 scopus 로고    scopus 로고
    • M-TOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
    • Fingar D.C., Richardson C.J., Tee A.R., Cheatham L., Tsou C., Blenis J. M-TOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol. Cell. Biol. 2004, 24:200-216.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 200-216
    • Fingar, D.C.1    Richardson, C.J.2    Tee, A.R.3    Cheatham, L.4    Tsou, C.5    Blenis, J.6
  • 12
    • 69449086580 scopus 로고    scopus 로고
    • Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)
    • Flynn E.J., Trent C.M., Rawls J.F. Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio). J. Lipid Res. 2009, 50:1641-1652.
    • (2009) J. Lipid Res. , vol.50 , pp. 1641-1652
    • Flynn, E.J.1    Trent, C.M.2    Rawls, J.F.3
  • 13
    • 0034823939 scopus 로고    scopus 로고
    • Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion
    • Gagnon A., Lau S., Sorisky A. Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion. J. Cell. Physiol. 2001, 189:14-22.
    • (2001) J. Cell. Physiol. , vol.189 , pp. 14-22
    • Gagnon, A.1    Lau, S.2    Sorisky, A.3
  • 14
    • 84864765761 scopus 로고    scopus 로고
    • Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish
    • Hasumura T., Shimada Y., Kuroyanagi J., Nishimura Y., Meguro S., Takema Y., Tanaka T. Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish. Nutrit. Metab. 2012, 9:73.
    • (2012) Nutrit. Metab. , vol.9 , pp. 73
    • Hasumura, T.1    Shimada, Y.2    Kuroyanagi, J.3    Nishimura, Y.4    Meguro, S.5    Takema, Y.6    Tanaka, T.7
  • 16
    • 0028180553 scopus 로고
    • Effects of baicalein and esculetin on transduction signals and growth factors expression in T-lymphoid leukemia cells
    • Huang H.C., Hsieh L.M., Chen H.W., Lin Y.S., Chen J.S. Effects of baicalein and esculetin on transduction signals and growth factors expression in T-lymphoid leukemia cells. Eur. J. Pharmacol. 1994, 268:73-78.
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 73-78
    • Huang, H.C.1    Hsieh, L.M.2    Chen, H.W.3    Lin, Y.S.4    Chen, J.S.5
  • 17
    • 0034025809 scopus 로고    scopus 로고
    • Antitumor effects of Scutellariae Radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines
    • Ikemoto S., Sugimura K., Yoshida N., Yasumoto R., Wada S., Yamamoto K., Kishimoto T. Antitumor effects of Scutellariae Radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. Urology 2000, 55:951-955.
    • (2000) Urology , vol.55 , pp. 951-955
    • Ikemoto, S.1    Sugimura, K.2    Yoshida, N.3    Yasumoto, R.4    Wada, S.5    Yamamoto, K.6    Kishimoto, T.7
  • 18
    • 0027296347 scopus 로고
    • Cell cycle analysis by flow cytometry: principles and applications
    • Jayat C., Ratinaud M.H. Cell cycle analysis by flow cytometry: principles and applications. Biol. Cell. 1993, 78:15-25.
    • (1993) Biol. Cell. , vol.78 , pp. 15-25
    • Jayat, C.1    Ratinaud, M.H.2
  • 21
    • 7044234995 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis
    • Kim J.E., Chen J. Regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis. Diabetes 2004, 53:2748-2756.
    • (2004) Diabetes , vol.53 , pp. 2748-2756
    • Kim, J.E.1    Chen, J.2
  • 22
    • 80053104570 scopus 로고    scopus 로고
    • Curcumin inhibits adipocyte differentiation through modulation of mitotic clonal expansion
    • Kim C.Y., Le T.T., Chen C., Cheng J.X., Kim K.H. Curcumin inhibits adipocyte differentiation through modulation of mitotic clonal expansion. J. Nutrit. Biochem. 2011, 22:910-920.
    • (2011) J. Nutrit. Biochem. , vol.22 , pp. 910-920
    • Kim, C.Y.1    Le, T.T.2    Chen, C.3    Cheng, J.X.4    Kim, K.H.5
  • 23
    • 0021228426 scopus 로고
    • Studies on Scutellariae Radix. VII. Anti-arthritic and anti-inflammatory actions of methanolic extract and flavonoid components from Scutellariae Radix
    • Kubo M., Matsuda H., Tanaka M., Kimura Y., Okuda H., Higashino M., Tani T., Namba K., Arichi S. Studies on Scutellariae Radix. VII. Anti-arthritic and anti-inflammatory actions of methanolic extract and flavonoid components from Scutellariae Radix. Chem. Pharmaceut. Bull. (Tokyo) 1984, 32:2724-2729.
    • (1984) Chem. Pharmaceut. Bull. (Tokyo) , vol.32 , pp. 2724-2729
    • Kubo, M.1    Matsuda, H.2    Tanaka, M.3    Kimura, Y.4    Okuda, H.5    Higashino, M.6    Tani, T.7    Namba, K.8    Arichi, S.9
  • 24
    • 70450204007 scopus 로고    scopus 로고
    • An emerging role of m-TOR in lipid biosynthesis
    • Laplante M., Sabatini D.M. An emerging role of m-TOR in lipid biosynthesis. Curr. Biol. 2009, 19:R1046-R1052.
    • (2009) Curr. Biol. , vol.19
    • Laplante, M.1    Sabatini, D.M.2
  • 25
    • 84858009261 scopus 로고    scopus 로고
    • Pycnogenol® inhibits lipid accumulation in 3T3-L1 adipocytes with the modulation of reactive oxygen species (ROS) production associated with antioxidant enzyme responses
    • Lee O.H., Seo M.J., Choi H.S., Lee B.Y. Pycnogenol® inhibits lipid accumulation in 3T3-L1 adipocytes with the modulation of reactive oxygen species (ROS) production associated with antioxidant enzyme responses. Phytother. Res. 2012, 26:403-411.
    • (2012) Phytother. Res. , vol.26 , pp. 403-411
    • Lee, O.H.1    Seo, M.J.2    Choi, H.S.3    Lee, B.Y.4
  • 27
    • 67349217986 scopus 로고    scopus 로고
    • Molecular mechanisms of m-TOR-mediated translational control
    • Ma X.M., Blenis J. Molecular mechanisms of m-TOR-mediated translational control. Nat. Rev. Mol. Cell Biol. 2009, 10:307-318.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 307-318
    • Ma, X.M.1    Blenis, J.2
  • 29
    • 0035657098 scopus 로고    scopus 로고
    • The art and design of genetic screens: zebrafish
    • Patton E.E., Zon L.I. The art and design of genetic screens: zebrafish. Nat. Rev. Genet. 2001, 2:956-966.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 956-966
    • Patton, E.E.1    Zon, L.I.2
  • 32
    • 0033830783 scopus 로고    scopus 로고
    • Transcriptional control of adipogenesis
    • Rangwala S.M., Lazar M.A. Transcriptional control of adipogenesis. Annu. Rev. Nutr. 2000, 20:535-559.
    • (2000) Annu. Rev. Nutr. , vol.20 , pp. 535-559
    • Rangwala, S.M.1    Lazar, M.A.2
  • 33
    • 0033552914 scopus 로고    scopus 로고
    • Analysis of cell cycle arrest in adipocyte differentiation
    • Reichert M., Eick D. Analysis of cell cycle arrest in adipocyte differentiation. Oncogene 1999, 18:459-466.
    • (1999) Oncogene , vol.18 , pp. 459-466
    • Reichert, M.1    Eick, D.2
  • 34
    • 80054057662 scopus 로고    scopus 로고
    • Mammalian triacylglycerol metabolism: synthesis, lipolysis and signaling
    • Rosalind A.C., Douglas G.M. Mammalian triacylglycerol metabolism: synthesis, lipolysis and signaling. Chem. Rev. 2011, 111:6359-6386.
    • (2011) Chem. Rev. , vol.111 , pp. 6359-6386
    • Rosalind, A.C.1    Douglas, G.M.2
  • 35
    • 0020429373 scopus 로고
    • Selective inhibition of platelet lipoxygenase by baicalein
    • Sekiya K., Okuda H. Selective inhibition of platelet lipoxygenase by baicalein. Biochem. Biophys. Res. Commun. 1982, 105:1090-1095.
    • (1982) Biochem. Biophys. Res. Commun. , vol.105 , pp. 1090-1095
    • Sekiya, K.1    Okuda, H.2
  • 37
    • 0027465113 scopus 로고
    • Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes
    • Spiegelman B.M., Choy L., Hotamisligil G.S., Graves R.A., Tontonoz P. Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes. J. Biol. Chem. 1993, 268:6823-6826.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6823-6826
    • Spiegelman, B.M.1    Choy, L.2    Hotamisligil, G.S.3    Graves, R.A.4    Tontonoz, P.5
  • 38
    • 0033200389 scopus 로고    scopus 로고
    • Activation and centromeric localization of CCAAT/enhancer binding proteins during the mitotic clonal expansion of adipocyte differentiation
    • Tang Q.Q., Lane M.D. Activation and centromeric localization of CCAAT/enhancer binding proteins during the mitotic clonal expansion of adipocyte differentiation. Genes Develop. 1999, 13:2231-2241.
    • (1999) Genes Develop. , vol.13 , pp. 2231-2241
    • Tang, Q.Q.1    Lane, M.D.2
  • 39
    • 0037422569 scopus 로고    scopus 로고
    • Mitotic clonal expansion: a synchronous process required for adipogenesis
    • Tang Q.Q., Otto T.C., Lane M.D. Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc. Natl. Acad. Sci. USA 2003, 100:44-49.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 44-49
    • Tang, Q.Q.1    Otto, T.C.2    Lane, M.D.3
  • 40
    • 33845322632 scopus 로고    scopus 로고
    • Pref-1, a preadipocyte secreted factor that inhibits adipogenesis
    • Wang Y., Kim K.A., Kim J.H., Sul H.S. Pref-1, a preadipocyte secreted factor that inhibits adipogenesis. J. Nutrit. 2006, 136:2953-2956.
    • (2006) J. Nutrit. , vol.136 , pp. 2953-2956
    • Wang, Y.1    Kim, K.A.2    Kim, J.H.3    Sul, H.S.4
  • 41
    • 0028885873 scopus 로고
    • Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells
    • Yeh W.C., Bierer B.E., McKnight S.L. Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. Proc. Natl. Acad. Sci. USA 1995, 92:11086-11090.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11086-11090
    • Yeh, W.C.1    Bierer, B.E.2    McKnight, S.L.3
  • 42
    • 50949098238 scopus 로고    scopus 로고
    • Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis
    • Zhang P., O'Loughlin L., Brindley D.N., Reue K. Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis. J. Lipid Res. 2008, 49:1519-1528.
    • (2008) J. Lipid Res. , vol.49 , pp. 1519-1528
    • Zhang, P.1    O'Loughlin, L.2    Brindley, D.N.3    Reue, K.4


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