Protective mechanisms of coenzyme-Q10 may involve up-regulation of testicular P-glycoprotein in doxorubicin-induced toxicity

Environmental Toxicology and Pharmacology

Volumn 37, Issue 2, 2014, Pages 772-781

  El Sheikh, Azza A K ^a   Morsy, Mohamed A ^a   Mahmoud, Marwa M ^a   Rifaai, Rehab A ^a  

^a Minia University   (Egypt)

Author keywords

Coenzyme Q10; Doxorubicin; P glycoprotein; Testicular toxicity

Indexed keywords

ANTIOXIDANT; CASPASE 3; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; UBIDECARENONE; ANTINEOPLASTIC ANTIBIOTIC; CATALASE; GLUTATHIONE; MALONALDEHYDE; NITRIC ACID DERIVATIVE; NITRITE; PROTECTIVE AGENT; UBIQUINONE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; HISTOPATHOLOGY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SINGLE DRUG DOSE; TESTIS INJURY; UPREGULATION; YOUNG ADULT; ANALOGS AND DERIVATIVES; ANIMAL; BODY WEIGHT; DRUG EFFECTS; METABOLISM; ORGAN SIZE; PATHOLOGY; TESTIS; TOXICITY; WISTAR RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BODY WEIGHT; CATALASE; DOXORUBICIN; GLUTATHIONE; MALE; MALONDIALDEHYDE; NITRATES; NITRITES; ORGAN SIZE; P-GLYCOPROTEIN; PROTECTIVE AGENTS; RATS, WISTAR; TESTIS; UBIQUINONE; UP-REGULATION;

EID: 84896038831     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2014.02.010     Document Type: Article

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