The hypoxic ventilatory response and TRPA1 antagonism in conscious mice

Acta Physiologica

Volumn 210, Issue 4, 2014, Pages 928-938

  Pokorski, M ^a,b   Takeda, K ^a   Sato, Y ^c   Okada, Y ^a  

^a NATIONAL HOSPITAL ORGANIZATION MURAYAMA MEDICAL CENTER   (Japan)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Carotid chemoreceptors; Chemosensing; Hypercapnia; Hyperventilation; Hypoxia; Oxygen sensor

Indexed keywords

N (4 ISOPROPYLPHENYL) 2 (1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXO 7H PURIN 7 YL)ACETAMIDE; OXYGEN; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY PLETHYSMOGRAPH; BREATHING RATE; CAROTID BODY CHEMORECEPTOR; CONTROLLED STUDY; HUMAN; HYPERCAPNIA; HYPOXIA; HYPOXIC VENTILATORY RESPONSE; LUNG MINUTE VOLUME; LUNG VENTILATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TIDAL VOLUME;

CAROTID CHEMORECEPTORS; CHEMOSENSING; HYPERCAPNIA; HYPERVENTILATION; HYPOXIA; OXYGEN SENSOR;

ACETANILIDES; ANIMALS; ANOXIA; CAROTID BODY; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED C57BL; OXYGEN CONSUMPTION; PULMONARY VENTILATION; PURINES; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84896036395     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12202     Document Type: Article

References (43)

1. Belvisi, M.G., Dubuis, E. & Birrell, M.A. 2011. Transient receptor potential A1 channels. Insights into cough and airway inflammatory diseases. Chest 140, 1040-1047.
2. Bessac, B.F., Sivula, M., von Hehn, C.A., Escalera, J., Cohn, L. & Jordt, S.E. 2008. TRPA1 is a major oxidant sensor in murine airway sensory neurons. J Clin Invest 118, 1899-1910.
3. 2+ concentrations. Annu Rev Pharmacol Toxicol 49, 395-426.
4. Borisenko, S.A. 1988. Effect of carbidopa and dimethyl sulfoxide on the permeability of the hemato-encephalic barrier for 14C-tyrosine and 14C-DOPA in rats. Biull Eksp Biol Med 106, 686-688 (Article in Russian).
5. Brouns, I., Pintelon, I., Timmermans, J.P. & Adriaensen, D. 2012. Novel insights in the neurochemistry and function of pulmonary sensory receptors. Adv Anat Embryol Cell Biol 211, 1-115.
6. Cardell, L.O., Lou, Y.P., Takeyama, K., Ueki, I.F., Lausier, J. & Nadel, J.A. 1998. Carbon monoxide, a cyclic GMP-related messenger, involved in hypoxic bronchodilation in vivo. Pulm Pharmacol Ther 11, 309-315.
7. Dillon, G.H. & Waldrop, T.G. 1993. Responses of feline caudal hypothalamic cardiorespiratory neurons to hypoxia and hypercapnia. Exp Brain Res 96, 260-272.
8. Eid, S.R., Crown, E.D., Moore, E.L., Liang, H.A., Choong, K.-C., Dima, S., Henze, D.A., Kane, S.A. & Urban, M.O. 2008. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Mol Pain 4, 48.
9. Ginsberg, M.D., Medoff, R. & Reivich, M. 1976. Heterogeneities of regional cerebral blood flow during hypoxia-ischemia in the rat. Stroke 7, 132-134.
10. Greenberg, H.E., Sica, A., Batson, D. & Scharf, S.M. 1999. Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia. J Appl Physiol 86, 298-305.
11. Honda, Y. 1985. Role of carotid chemoreceptors in control of breathing at rest and in exercise: studies on human subjects with bilateral carotid body resection. Jpn J Physiol 35, 535-544.
12. Hondoha, A., Ishidab, Y., Ugawab, S., Uedab, T., Shibatab, Y., Yamadab, T., Shikanob, M., Murakamia, S. & Shimadab, S. 2010. Distinct expression of cold receptors (TRPM8 and TRPA1) in the rat nodose-petrosal ganglion complex. Brain Res 1319, 60-69.
13. Hsu, C.C., Lin, R.L., Lee, L.Y. & Lin, Y.S. 2013. Hydrogen sulfide induces hypersensitivity of rat capsaicin-sensitive lung vagal neurons: role of TRPA1 receptors. Am J Physiol Regul Integr Comp Physiol 305, R769-R779.
14. Ichinose, M., Inoue, H., Miura, M., Yafuso, N., Nogami, H. & Takishima, T. 1987. Possible sensory receptor of nonadrenergic inhibitory nervous system. J Appl Physiol 63, 923-929.
15. Kim, Y.S., Son, J.Y., Kim, T.H., Paik, S.K., Dai, Y., Noguchi, K., Ahn, D.K. & Bae, Y.C. 2010. Expression of transient receptor potential ankyrin 1 (TRPA1) in the rat trigeminal sensory afferents and spinal dorsal horn. J Comp Neurol 518, 687-698.
16. Kunert-Keil, C., Bisping, F., Krüger, J. & Brinkmeier, H. 2006. Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains. BMC Genomics 7, 159.
17. Lee, S.M., Cho, Y.S., Kim, T.H., Jin, M.U., Ahn, D.K., Noguchi, K. & Bae, Y.C. 2012. An ultrastructural evidence for the expression of transient receptor potential ankyrin 1 (TRPA1) in astrocytes in the rat trigeminal caudal nucleus. J Chem Neuroanat 45, 45-49.
18. Lembrechts, R., Brouns, I., Schnorbusch, K., Pintelon, I., Kemp, P.J., Timmermans, J.P., Riccardi, D. & Adriaensen, D. 2013. Functional expression of the multimodal extracellular calcium-sensing receptor in pulmonary neuroendocrine cells. J Cell Sci 126, 4490-4501.
19. Marczak, M. & Pokorski, M. 2003. Oxygen breathing and ventilation. J Physiol Pharmacol 55, 127-134.
20. Matta, J.A., Cirnett, P.M., Miyares, R.L., Abe, K., Sahibzada, N. & Ahern, G.P. 2008. General anesthetics activate a nociceptive ion channel to enhance pain and inflammation. Proc Natl Acad Sci USA 105, 8784-8789.
21. McNamara, C.R., Mandel-Brehm, J., Bautista, D.M., Siemens, J., Deranian, K.L., Zhao, M., Hayward, N.J., Chong, J.A., Julius, D., Moran, M.M. & Fanger, C.M. 2007. TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA 104, 13525-13530.
22. Nassenstein, C., Kwong, K., Taylor-Clark, T., Kollarik, M., Macglashan, D.M., Braun, A. & Undem, B.J. 2008. Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs. J Physiol 586, 1595-1604.
23. Nilius, B., Appendino, G. & Owsianik, G. 2012. The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflügers Arch 464, 425-458.
24. 2+ channels in stimulus-evoked catecholamine release from chemoreceptor cells of the carotid body. Neuroscience 47, 463-472.
25. Peers, C. & Buckler, K.J. 1995. Transduction of chemostimuli by the type I carotid body cells. J Membr Biol 144, 1-9.
26. Persson, P.B. & Henriksson, J. 2011. Good publication practise in physiol. Acta Physiol (Oxford) 203, 403-407.
27. Piskuric, N.A., Vollmer, C. & Nurse, C.A. 2011. Confocal immunofluorescence study of rat aortic body chemoreceptors and associated neurons in situ and in vitro. J Comp Neurol 519, 856-873.
28. Pokorski, M. & Antosiewicz, J. 2012. Hypoxic ventilatory response in limited iron in the rat. J Biol Regul Homeost Agents 26, 653-661.
29. Pokorski, M. & Lahiri, S. 1983. Relative peripheral and central chemosensory responses to metabolic alkalosis. Am J Physiol Regul Integr Comp Physiol 245, R873-R880.
30. Pokorski, M. & Strosznajder, R. 1992. Phosphoinositides and signal transduction in the cat carotid body. In: Y. Honda, Y. Miyamoto, K. Konno & J.G. Widdicombe, (eds) Control of Breathing and Its Modelling Perspective, pp. 367-370. Plenum, New York.
31. Pokorski, M., Mokashi, A., Mulligan, E., Nishiro, T. & Lahiri, S. 1981. Responses of aortic chemoreceptors before and after pneumothorax in the cat. J Appl Physiol 51, 665-670.
32. Pokorski, M., Faff, L. & Di Giulio, C. 2012a. Hypoxic redistribution of iron and calcium in the cat glomus cells. Adv Exp Med Biol 758, 99-103.
33. Pokorski, M., Sakagami, H. & Okada, Y. 2012b. Calcium/calmodulin-dependent protein kinases in the carotid body: an immunohistochemical study. SpringerPlus 1, 16.
34. Ponte, J. & Sadler, C.L. 1989. Interactions between hypoxia, acetylcholine and dopamine in the carotid body of rabbit and cat. J Physiol 410, 395-410.
35. Rech, J.C., Eckert, W.A., Maher, M.P., Banke, T., Bhattacharya, A. & Wickenden, A.D. 2010. Recent advances in the biology and medicinal chemistry of TRPA1. Future Med Chem 2, 843-858.
36. Soliz, J., Soulage, C., Borter, E., van Patot, M.T. & Gassmann, M. 2008. Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice. Am J Physiol Regul Integr Comp Physiol 295, R649-R658.
37. Story, G.M., Peier, A.M., Reeve, A.J., Eid, S.R., Mosbacher, J., Hricik, T.R., Earley, T.J., Hergarden, A.C., Andersson, D.A., Hwang, S.W., McIntyre, P., Jegla, T., Bevan, S. & Patapoutian, A. 2003. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112, 819-829.
38. Sun, B., Bang, S.I. & Jin, Y.H. 2009. Transient receptor potential A1 increase glutamate release on brain stem neurons. NeuroReport 20, 1002-1006.
39. 2. Nat Chem Biol 7, 701-711.
40. Taylor-Clark, T.E. & Undem, B.J. 2011. Sensing pulmonary oxidative stress by lung vagal afferents. Respir Physiol Neurobiol 178, 406-413.
41. Ward, J.P. 2008. Oxygen sensors in context. Biochim Biophys Acta 1777, 1-14.
42. Weller, K., Reeh, P.W. & Sauer, S.K. 2011. TRPV1, TRPA1, and CB1 in the isolated vagus nerve-axonal chemosensitivity and control of neuropeptide release. Neuropeptides 45, 391-400.
43. Wetzel, R.C., Herold, C.J., Zerhouni, E.A. & Robotham, J.L. 1992. Hypoxic bronchodilation. J Appl Physiol 73, 1202-1206.