Hypoxic redistribution of iron and calcium in the cat glomus cells

Advances in Experimental Medicine and Biology

Volumn 758, Issue , 2012, Pages 99-103

  Pokorski, Mieczyslaw ^a   Faff, Lidia ^a   Di Giulio, Camillo ^b  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

Calcium; Carotid body; Chemoreceptor cells; Hypoxia; Iron

Indexed keywords

CALCIUM; IRON;

ANIMAL CELL; CALCIUM CELL LEVEL; CAROTID BODY; CELL COMPOSITION; CELL HYPOXIA; CELL NUCLEUS; CELL VACUOLE; CHEMORECEPTOR; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPLASM; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; ROENTGEN SPECTROSCOPY; TISSUE SLICE;

EID: 84870416315     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-94-007-4584-1_13     Document Type: Conference Paper

References (15)

1. Baby SM, Roy A, Mokashi AM, Lahiri S (2003) Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1 a and -1 b in the rat carotid body and glomus cells. Histochem Cell Biol 120:343-352
2. Buerk DG, Osanai S, Chugh DK, Mokashi A, Lahiri S (1997) Calcium-dependent O2 sensitivity of cat carotid body. Adv Exp Med Biol 411:1-5
3. Conde SV, Caceres AI, Vicario I, Rocher A, Obeso A, Gonzalez C (2006) An overview on the homeostasis of Ca2+ in glomus cells of the rabbit and rat carotid bodies. Adv Exp Med Biol 580:215-222
4. Daudu PA, Roy A, Rozanov C, Mokashi A, Lahiri S (2002) Extra- and intracellular free iron and the carotid body responses. Respir Physiol Neurobiol 130:21-31
5. Faff L, van der Meulen H, Koerten HK, Walski M, Pokorski M (2001) Calcium handling by the cat carotid body - a pyroantimonate study. Acta Hisotochem 103:305-313
6. Fandrey J, Gassmann M (2009) Oxygen sensing and the activation of the hypoxia inducible factor 1 (HIF-1). Adv Exp Med Biol 648:197-206
7. Kell DB (2009) Iron behaving badly: Inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive in fl ammatory and degenerative diseases. BMC Med Genomics 2:2. doi: 10.1186/1755-8794-2-2
8. Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J (2004) Hepcidin regulates cellular iron ef fl ux by binding to ferroportin and inducing its internalization. Science 306:2090-2093
9. Nguyen MVC, Pouvreau S, El Hajjaji FZ, Denavit-Saubie M, Pequignot JM (2007) Desferrioxamine enhances hypoxic ventilatory response and induces tyrosine hydroxylase gene expression in the rat brainstem in vivo. J Neurosci Res 1119-1125
10. Nicolas G, Chauvet C, Viatte L, Danan JL, Bigard X, Devaux I, Beaumont C, Kahn A, Vaulont S (2002) The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and in fl ammation. J Clin Invest 110:1037-1044
11. Pokorski M, Sakagami H, Kondo H (2000) Classical protein kinase C and its hypoxic stimulus-induced translocation in the cat and rat carotid body. Eur Respir J 16:459-463
12. Pokorski M, Antosiewicz J, Di Giulio C, Lahiri S (2009) Iron chelation and the ventilatory response to hypoxia. Adv Exp Med Biol 648:215-221
13. Roy A, Li J, Baby SM, Mokashi A, Burek DG, Lahiri S (2004a) Effects of iron-chelators on ion-channels and HIF-1 a in the carotid body. Respir Physiol Neurobiol 141:115-123
14. Roy A, Volgin DV, Baby SM, Mokashi A, Kubin L, Lahiri S (2004b) Activation of HIF-1 a mRNA by hypoxia and iron chelator in isolated rat carotid body. Neurosci Lett 363:229-232
15. Strosznajder RP, Pokorski M (2000) Regulation of phospholipase C activity by calcium ions and guanine nucleotide in the normoxic cat carotid body. Neurochem Res 25:739-743