Epstein-Barr virus maintains lymphomas via its miRNAs

Oncogene

Volumn 33, Issue 10, 2014, Pages 1258-1264

  Vereide, D T ^a   Seto, E ^b,c   Chiu, Y F ^a   Hayes, M ^a   Tagawa, T ^b,c   Grundhoff, A ^d   Hammerschmidt, W ^b,c   Sugden, B ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b German Center for Infection Research   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

apoptosis; BART miRNAs; Burkitt's lymphoma; EBV; RISC IP

Indexed keywords

CASPASE 3; MICRORNA;

APOPTOSIS; ARTICLE; B LYMPHOCYTE; BURKITT LYMPHOMA CELL; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; LYMPHOCYTE TRANSFORMATION; LYMPHOMA CELL; NONHUMAN; PRIORITY JOURNAL; VIRUS ONCOGENE;

HUMAN HERPESVIRUS 4;

APOPTOSIS; B-LYMPHOCYTES; BASE SEQUENCE; BINDING SITES; BURKITT LYMPHOMA; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; EPSTEIN-BARR VIRUS NUCLEAR ANTIGENS; GENE EXPRESSION REGULATION, NEOPLASTIC; HERPESVIRUS 4, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; MICRORNAS; RNA INTERFERENCE;

EID: 84895920376     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.71     Document Type: Article

References (30)

1. Nanbo A, Sugden A, Sugden B. The coupling of synthesis and partitioning of EBV's plasmid replicon is revealed in live cells. EMBO J 2007; 26: 4252-4262
2. Vereide D, Sugden B. Insights into the evolution of lymphomas induced by Epstein-Barr virus. Advances in cancer research 2010; 108: 1-19
3. Vereide DT, Sugden B. Lymphomas differ in their dependence on Epstein-Barr virus. Blood 2011; 117: 1977-1985
4. Kirchmaier AL, Sugden B. Dominant-negative inhibitors of EBNA-1 of Epstein-Barr virus. J Virol 1997; 71: 1766-1775
5. Kelly G, Bell A, Rickinson A. Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2. Nat Med 2002; 8: 1098-1104
6. Kuzembayeva M, Chiu YF, Sugden B. Comparing proteomics and RISC immunoprecipitations to identify targets of Epstein-Barr viral miRNAs. PLoS One 2012; 7: E47409
7. Choy EY, Siu KL, Kok KH, Lung RW, Tsang CM, To KF et al. An Epstein-Barr virusencoded microRNA targets PUMA to promote host cell survival. J Exp Med 2008; 205: 2551-2560
8. Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 2008; 132: 875-886
9. Oliver PM, Vass T, Kappler J, Marrack P. Loss of the proapoptotic protein, Bim, breaks B cell anergy. J Exp Med 2006; 203: 731-741
10. Anderton E, Yee J, Smith P, Crook T, White RE, Allday MJ. Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumoursuppressor Bim: Clues to the pathogenesis of Burkitt's lymphoma. Oncogene 2008; 27: 421-433
11. Clybouw C, McHichi B, Mouhamad S, Auffredou MT, Bourgeade MF, Sharma S et al. EBV infection of human B lymphocytes leads to down-regulation of Bim expression: Relationship to resistance to apoptosis. J Immunol 2005; 175: 2968-2973
12. Paschos K, Smith P, Anderton E, Middeldorp JM, White RE, Allday MJ. Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim. PLoS Pathog 2009; 5: E1000492
13. Bartel DP. MicroRNAs: Target recognition and regulatory functions. Cell 2009; 136: 215-233
14. Rajewsky N. microRNA target predictions in animals. Nat Genet 2006; 38(Suppl): S8-S13
15. Grundhoff A, Sullivan CS, Ganem D. A combined computational and microarraybased approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA 2006; 12: 733-750
16. Schafer A, Cai X, Bilello JP, Desrosiers RC, Cullen BR. Cloning and analysis of microRNAs encoded by the primate gamma-herpesvirus rhesus monkey rhadinovirus. Virology 2007; 364: 21-27
17. Walz N, Christalla T, Tessmer U, Grundhoff A. A global analysis of evolutionary conservation among known and predicted gammaherpesvirus microRNAs. J Virol 2010; 84: 716-728
18. Birkenbach M, Josefsen K, Yalamanchili R, Lenoir G, Kieff E. Epstein-Barr virusinduced genes: First lymphocyte-specific G protein-coupled peptide receptors. J Virol 1993; 67: 2209-2220
19. Riley KJ, Rabinowitz GS, Yario TA, Luna JM, Darnell RB, Steitz JA. EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency. EMBO J 2012; 31: 2207-2221
20. Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Kang D, Hafner M et al. The viral and cellular microRNA targetome in lymphoblastoid cell lines. PLoS Pathog 2012; 8: E1002484
21. Dolken L, Malterer G, Erhard F, Kothe S, Friedel CC, Suffert G et al. Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay. Cell Host Microbe 2010; 7: 324-334
22. Niwa H, Yamamura K, Miyazaki J. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 1991; 108: 193-199
23. Seto E, Moosmann A, Gromminger S, Walz N, Grundhoff A, Hammerschmidt W. Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. PLoS Pathogens 2010; 6: E1001063
24. Suffert G, Malterer G, Hausser J, Viiliainen J, Fender A, Contrant M et al. Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis. PLoS Pathogens 2011; 7: E1002405
25. Lee DY, Sugden B. The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis. Blood 2008; 111: 2280-2289
26. Gaillard C, Strauss F. Ethanol precipitation of DNA with linear polyacrylamide as carrier. Nucleic Acids Res 1990; 18: 378
27. Pratt ZL, Kuzembayeva M, Sengupta S, Sugden B. The microRNAs of Epstein-Barr Virus are expressed at dramatically differing levels among cell lines. Virology 2009; 386: 387-397
28. Pratt ZL, Zhang J, Sugden B. The latent membrane protein 1 (LMP1) oncogene of Epstein-Barr virus can simultaneously induce and inhibit apoptosis in B cells. J Virol 2012; 86: 4380-4393
29. Pruitt KD, Tatusova T, Klimke W, Maglott DR. NCBI reference sequences: Current status, policy and new initiatives. Nucleic Acids Res 2009; 37: D32-D36
30. Altmann M, Hammerschmidt W. Epstein-Barr virus provides a new paradigm: A requirement for the immediate inhibition of apoptosis. PLoS Biol 2005; 3: E404