Human protein aging: Modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates

Aging Cell

Volumn 13, Issue 2, 2014, Pages 226-234

  Wang, Zhen ^a   Lyons, Brian ^b   Truscott, Roger J W ^c   Schey, Kevin L ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

Aging; Glutathione; Lens; Protein protein crosslinking

Indexed keywords

AMINO ACID; BETA CRYSTALLIN; DEHYDROALANINE; DEHYDROBUTYRINE; GLUTATHIONE; LENS PROTEIN; PHOSPHORIC ACID; PHOSPHOSERINE; PHOSPHOTHREONINE; SERINE; THREONINE; UNCLASSIFIED DRUG;

ADULT; AGED; AGING; ARTICLE; BETA ELIMINATION; CATARACT; ELIMINATION REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; METABOLITE; MIDDLE AGED; NUCLEOPHILICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CROSS LINKING; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; TANDEM MASS SPECTROMETRY; VERY ELDERLY;

AGING; GLUTATHIONE; LENS; PROTEIN-PROTEIN CROSSLINKING;

ADULT; AGED, 80 AND OVER; ALANINE; AMINO ACID SEQUENCE; AMINOBUTYRATES; CELL NUCLEUS; CROSS-LINKING REAGENTS; CRYSTALLINS; GLUTATHIONE; HUMANS; LENS, CRYSTALLINE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE; TANDEM MASS SPECTROMETRY; THREONINE; TIME FACTORS;

EID: 84895822337     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12164     Document Type: Article

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