Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 9, 2014, Pages 3602-3607

  Ma, Hongwei ^a   Thapa, Arjun ^a   Morris, Lynsie ^a   Redmond, T Michael ^b   Baehr, Wolfgang ^c   Ding, Xi Qin ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONE OPSIN; CYCLIC NUCLEOTIDE GATED CHANNEL; CYCLIC NUCLEOTIDE GATED CHANNEL B SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANYLATE CYCLASE; ISOMERASE; LIOTHYRONINE; RETINOL ISOMERASE; SODIUM PERCHLORATE; THIAMAZOLE; THYROID HORMONE; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL VIABILITY; COLOR BLINDNESS; CONTROLLED STUDY; DISEASE SEVERITY; HORMONE INHIBITION; LEBER CONGENITAL AMAUROSIS; LIOTHYRONINE BLOOD LEVEL; MOUSE; MOUSE MODEL; NEWBORN; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECESSIVE INHERITANCE; RETINA CONE; RETINA DEGENERATION; RETINA DYSTROPHY; SIGNAL TRANSDUCTION;

ANIMALS; ANTITHYROID AGENTS; CIS-TRANS-ISOMERASES; COLOR VISION DEFECTS; CONE OPSINS; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; GUANYLATE CYCLASE; LEBER CONGENITAL AMAUROSIS; METHIMAZOLE; MICE; MICE, KNOCKOUT; RECEPTORS, CELL SURFACE; RETINAL CONE PHOTORECEPTOR CELLS; RETINAL DEGENERATION; SIGNAL TRANSDUCTION; THYROID HORMONES; TRIIODOTHYRONINE;

EID: 84895799338     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1317041111     Document Type: Article

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