3, 3′5 triiodo l thyronine induces apoptosis in human breast cancer MCF-7cells, repressing SMP30 expression through negative thyroid response elements

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Sar, Pranati ^a   Peter, Rosalima ^a   Rath, Bandita ^a   Das Mohapatra, Aloks ^a   Mishra, Sandip K ^a  

^a INSTITUTE OF LIFE SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3,3',5' TRIIODOTHYRONINE; HISTONE H3; REGUCALCIN; RETINOID X RECEPTOR ALPHA; STEROID RECEPTOR COACTIVATOR 1; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR ALPHA; TRICHOSTATIN A; CALCIUM BINDING PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; RGN PROTEIN, HUMAN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SIGNAL PEPTIDE; THYROID HORMONE RECEPTOR BETA;

APOPTOSIS; ARTICLE; CANCER CELL; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; GENE REPRESSION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; PROMOTER REGION; PROTEIN EXPRESSION; SENESCENCE MARKER PROTEIN 30 GENE; THYROID RESPONSE ELEMENT; TRANSACTIVATION; BINDING SITE; BREAST TUMOR; CELL STRAIN HEK293; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; METASTASIS; PATHOLOGY; THYROID GLAND; TRANSCRIPTION INITIATION;

RATTUS;

APOPTOSIS; BINDING SITES; BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOPLASM METASTASIS; PROMOTER REGIONS, GENETIC; RESPONSE ELEMENTS; SELECTIVE ESTROGEN RECEPTOR MODULATORS; THYROID GLAND; THYROID HORMONE RECEPTORS BETA; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRIIODOTHYRONINE, REVERSE;

EID: 79958127005     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020861     Document Type: Article

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