Integration of sequence data from a consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Okada, Yukinori ^a,b,c,d   Diogo, Dorothee ^a,b   Greenberg, Jeffrey D ^e   Mouassess, Faten ^f   Achkar, Walid A L ^f   Fulton, Robert S ^g   Denny, Joshua C ^h   Gupta, Namrata ^b   Mirel, Daniel ^b   Gabriel, Stacy ^b   Li, Gang ^a   Kremer, Joel M ⁱ   Pappas, Dimitrios A ^j   Carroll, Robert J ^h   Eyler, Anne E ^h   Trynka, Gosia ^a,b   Stahl, Eli A ^k   Cui, Jing ^a   Saxena, Richa ^l   Coenen, Marieke J H ^m   Guchelaar, Henk Jan ⁿ   Huizinga, Tom W J ⁿ   Dieudé, Philippe ^o,p   Mariette, Xavier ^q   Barton, Anne ^r   Canhão, Helena ^s,t   Fonseca, João E ^s,t   De Vries, Niek ^u   Tak, Paul P ^u,v   Moreland, Larry W ^w   Bridges Jr , S Louis ^x   Miceli Richard, Corinne ^q   Choi, Hyon K ^a,y   Kamatani, Yoichiro ^d,z   Galan, Pilar ^aa   Lathrop, Mark ^ab   Raj, Towfique ^a,b,l   De Jager, Philip L ^a,b,l   Raychaudhuri, Soumya ^a,b,ac   Worthington, Jane ^r,ac   Padyukov, Leonid ^ad   Klareskog, Lars ^ad   Siminovitch, Katherine A ^ae,af,ag   Gregersen, Peter K ^ah   Mardis, Elaine R ^g   Arayssi, Thurayya ^ai   Kazkaz, Layla A ^aj,ak   Plenge, Robert M ^a,b   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d Institute of Physical and Chemical Research   (Japan)

^e NYU HOSPITAL FOR JOINT DISEASES   (United States)

^f Department of Molecular Biology and Biotechnology   (Syrian Arab Republic)

^g WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ Center for Rheumatology LLP   (United States)

^j Och Spine at New York Presbyterian Hospitals   (United States)

^k MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^l MASSACHUSETTS GENERAL HOSPITAL   (United States)

^m RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

ⁿ LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^o BICHAT HOSPITAL   (France)

^p UNIVERSITÉ PARIS DESCARTES   (France)

^q INSERM   (France)

^r UNIVERSITY OF MANCHESTER   (United Kingdom)

^s INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^t HOSPITAL DE SANTA MARIA   (Portugal)

^u UNIVERSITY OF AMSTERDAM   (Netherlands)

^v GLAXOSMITHKLINE   (United Kingdom)

^w UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^x University of Alabama at Birmingham   (United States)

^y BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^z FONDATION JEAN DAUSSET CEPH   (France)

^aa UNIVERSITÉ PARIS 13   (France)

^ab MCGILL UNIVERSITY   (Canada)

^ac MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^ad KAROLINSKA INSTITUTE   (Sweden)

^ae MOUNT SINAI HOSPITAL   (Canada)

^af UNIVERSITY HEALTH NETWORK   (Canada)

^ag UNIVERSITY OF TORONTO   (Canada)

^ah Northwell Health   (United States)

^ai WEILL CORNELL MEDICAL COLLEGE   (Qatar)

^aj Tishreen Hospital   (Syrian Arab Republic)

^ak Syrian Association for Rheumatology   (Syrian Arab Republic)

more..

Author keywords

[No Author keywords available]

Indexed keywords

LYSOPHOSPHOLIPASE;

ADULT; ALLELE; ARTICLE; CONSANGUINITY; CONTROLLED STUDY; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC RISK; HUMAN; IDENTITY; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PLB1 GENE; POPULATION DISPERSION; PROGENY; RHEUMATOID ARTHRITIS; SEQUENCE DATABASE; SINGLE NUCLEOTIDE POLYMORPHISM;

ARTHRITIS, RHEUMATOID; BASE SEQUENCE; COHORT STUDIES; CONSANGUINITY; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXOME; EXONS; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LYSOPHOSPHOLIPASE; MALE; META-ANALYSIS AS TOPIC; MUTATION; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; RISK FACTORS;

EID: 84895770158     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087645     Document Type: Article

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