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Volumn 944, Issue , 2014, Pages 101-106
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A HPLC-MS/MS method for the simultaneous quantitation of six alkaloids of Rhizoma Corydalis Decumbentis in rat plasma and its application to a pharmacokinetic study
a
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Author keywords
Alkaloid; HPLC MS MS; Pharmacokinetics; Rat plasma; Rhizoma Corydalis Decumbentis
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Indexed keywords
ALKALOIDS;
BODY FLUIDS;
ELECTROSPRAY IONIZATION;
NITROGEN COMPOUNDS;
PHARMACOKINETICS;
ELECTROSPRAY IONIZATION (ESI);
HPLC-MS/MS;
PHARMACOKINETIC STUDIES;
PROTEIN PRECIPITATION;
RAT PLASMA;
RHIZOMA CORYDALIS DECUMBENTIS;
SIMULTANEOUS DETERMINATIONS;
TRIPLE-QUADRUPOLE MASS SPECTROMETRY;
METABOLITES;
BERBERINE;
BICUCULLINE;
JATRORRHIZINE;
PALMATINE;
PARACETAMOL;
PROTOPINE;
TETRAHYDROPALMATINE;
ACCURACY;
ANIMAL EXPERIMENT;
AREA UNDER THE CURVE;
ARTICLE;
CALIBRATION;
CONTROL;
CONTROLLED STUDY;
CORYDALIS;
CORYDALIS DECUMBENTIS;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG HALF LIFE;
ELECTROSPRAY MASS SPECTROMETRY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
LIMIT OF QUANTITATION;
MALE;
MAXIMUM PLASMA CONCENTRATION;
NONHUMAN;
PLASMA CONCENTRATION-TIME CURVE;
PRIORITY JOURNAL;
QUADRUPOLE MASS SPECTROMETRY;
RAT;
RHIZOME;
TANDEM MASS SPECTROMETRY;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;
ALKALOID;
HPLC-MS/MS;
PHARMACOKINETICS;
RAT PLASMA;
RHIZOMA CORYDALIS DECUMBENTIS;
ALKALOIDS;
ANIMALS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CORYDALIS;
LINEAR MODELS;
MALE;
PLANT EXTRACTS;
RATS;
RATS, SPRAGUE-DAWLEY;
REPRODUCIBILITY OF RESULTS;
RHIZOME;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
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EID: 84895765424
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2013.11.010 Document Type: Article |
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Times cited : (24)
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References (7)
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