Protective action of corynoline, acetylcorynoline and protopine against experimental liver injury in mice

Yaoxue Xuebao

Volumn 32, Issue 5, 1997, Pages 331-336

  Wei, H L ^a   Liu, G T ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Acetyl corynoline; Corynoline; Cytochrome P450; Liver damage; Protopine

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALOID; BENZOPHENANTHRIDINE DERIVATIVE; BERBERINE DERIVATIVE; CYTOCHROME P450; PARACETAMOL; PROTOPINE; THIOACETAMIDE;

ANIMAL; ARTICLE; BLOOD; INTOXICATION; LIVER; LIVER MICROSOME; MALE; METABOLISM; MOUSE; PATHOLOGY; TOXIC HEPATITIS;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ALKALOIDS; ANIMALS; BENZOPHENANTHRIDINES; BERBERINE ALKALOIDS; CARBON TETRACHLORIDE POISONING; CYTOCHROME P-450 ENZYME SYSTEM; HEPATITIS, TOXIC; LIVER; MALE; MICE; MICROSOMES, LIVER; THIOACETAMIDE;

EID: 0031128940     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Fang OL, Lin M, Weng QM. Chemical study of alkaloids from Corydalis lonspersa . Planta Med, 1984,50:25
2. Chen YY, Shu ZB, Li LN. Studies on Fructus schisandrae. IV. Isolation and determination of the active compounds (in lowering high SGPT levels) of Schisandrae chinensis Bail. Sci Sin, 1976,19:276
3. Bao TT, Xu GF, Liu GT, et al. A comparison of the pharmacological actions of seven constitutents isolated from Fructus Schizandrae. Acta Pharm Sin, 1979,14:1
4. Liu KT, Lesca P. Pharmacological properties of dibenzo (a, c) cyclooctene derivatives isolated from Fructus Schizandrae chinensis. II. Induction of phenobarbital-like hepatic monoxygenases. Chem Biol Interact, 1982,39:315
5. Lowry, OH, Rosebrough, NJ, Farr AL, et al. Protein measurement with the Folinphenol reagent. J Biol Chem, 1951,193:265
6. Omura T, Sato R. The carbon monoxide pigment of liver microsomes. 1. Evidence for its haemoprotein nature. J Biol Chem, 1964,239:2370
7. French JS, Coon MJ. Properties of NADPH-cytochrome P450 reductase purified from rabbit liver microsomes. Arch Biochem Biophys, 1979,195:565
8. Brodie BB, Axelrod J. The fate of aminopyrine (pyramidon) in man and methods for the estimation of aminopyrine and its metabolites in biological material. J Pharmacol Exp Ther, 1950,99:171
9. Jerina DM, Dansette PM, Lu AYH, et al. Hepatic microosmal epoxide hydrase: a sensitive radiometric assay for hydration of arene oxide of carcinogenic aromatic hydrocarbons. Mol Pharmacol, 1972,13:342
10. King J. A study of human serum transaminase. J Med Lab Technol, 1960,17:1
11. Wolf CR, Harrelson Jr, Nastainczyk WM, et al. Metabolism of carbon tetrachloride in hepatic microsomes and reconstituted monooxygenase systems and its relationship to lipid peroxidation. Mol Pharmacol, 1980,18:553
12. Buege JA, Aust SD. Microsomal lipid peroxidation, In: Fleischer S, Packer L, eds. Method in Enzymology. Vol III. Biomembranes Part C. New York: Academic Press, 1978:302
13. Schanne FAX. Galactosamine-induced cell death in primary cultures of hepatocytes. Am J Pathol, 1980,100:25