Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes

Cell Metabolism

Volumn 19, Issue 3, 2014, Pages 484-497

  Lee, Sahmin ^a   Lee, Hyun Chae ^b   Kwon, Yoo Wook ^b   Lee, Sang Eun ^a   Cho, Youngjin ^a   Kim, Joonoh ^b   Lee, Soobeom ^b   Kim, Ju Young ^b   Lee, Jaewon ^b   Yang, Han Mo ^a   Mook Jung, Inhee ^a   Nam, Ky Youb ^c,d   Chung, Junho ^a   Lazar, Mitchell A ^e   Kim, Hyo Soo ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Yonsei University   (South Korea)

^d Gachon University   (South Korea)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADENYLYL CYCLASE ASSOCIATED PROTEIN 1; BINDING PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RESISTIN; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WHITE ADIPOSE TISSUE;

AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE PROTEINS; CELL LINE; CYCLIC AMP; CYTOKINES; CYTOSKELETAL PROTEINS; HEK293 CELLS; HUMANS; MICE; MICE, TRANSGENIC; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MONOCYTES; NF-KAPPA B; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RESISTIN; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84895761930     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.01.013     Document Type: Article

References (45)

1. B. Aruna, S. Ghosh, A.K. Singh, S.C. Mande, V. Srinivas, R. Chauhan, and N.Z. Ehtesham Human recombinant resistin protein displays a tendency to aggregate by forming intermolecular disulfide linkages Biochemistry 42 2003 10554 10559
2. B. Aruna, A. Islam, S. Ghosh, A.K. Singh, M. Vijayalakshmi, F. Ahmad, and N.Z. Ehtesham Biophysical analyses of human resistin: oligomer formation suggests novel biological function Biochemistry 47 2008 12457 12466
3. M. Bokarewa, I. Nagaev, L. Dahlberg, U. Smith, and A. Tarkowski Resistin, an adipokine with potent proinflammatory properties J. Immunol. 174 2005 5789 5795
4. M.S. Burnett, C.W. Lee, T.D. Kinnaird, E. Stabile, S. Durrani, M.K. Dullum, J.M. Devaney, C. Fishman, S. Stamou, and D. Canos et al. The potential role of resistin in atherogenesis Atherosclerosis 182 2005 241 248
5. R. Chen, and Z. Weng A novel shape complementarity scoring function for protein-protein docking Proteins 51 2003 397 408
6. R. Chen, L. Li, and Z. Weng ZDOCK: an initial-stage protein-docking algorithm Proteins 52 2003 80 87
7. Y. Cheng, and W.H. Prusoff Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction Biochem. Pharmacol. 22 1973 3099 3108
8. Y. Cho, S.E. Lee, H.C. Lee, J. Hur, S. Lee, S.W. Youn, J. Lee, H.J. Lee, T.K. Lee, and J. Park et al. Adipokine resistin is a key player to modulate monocytes, endothelial cells, and smooth muscle cells, leading to progression of atherosclerosis in rabbit carotid artery J. Am. Coll. Cardiol. 57 2011 99 109
9. A.C. Daquinag, Y. Zhang, F. Amaya-Manzanares, P.J. Simmons, and M.G. Kolonin An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells Cell Stem Cell 9 2011 74 86
10. N. Fernandez-Fuentes, B.K. Rai, C.J. Madrid-Aliste, J.E. Fajardo, and A. Fiser Comparative protein structure modeling by combining multiple templates and optimizing sequence-to-structure alignments Bioinformatics 23 2007 2558 2565
11. J. Field, A. Vojtek, R. Ballester, G. Bolger, J. Colicelli, K. Ferguson, J. Gerst, T. Kataoka, T. Michaeli, and S. Powers et al. Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein Cell 61 1990 319 327
12. N.L. Freeman, T. Lila, K.A. Mintzer, Z. Chen, A.J. Pahk, R. Ren, D.G. Drubin, and J. Field A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localization Mol. Cell. Biol. 16 1996 548 556
13. M. Gerber, A. Boettner, B. Seidel, A. Lammert, J. Bär, E. Schuster, J. Thiery, W. Kiess, and J. Kratzsch Serum resistin levels of obese and lean children and adolescents: biochemical analysis and clinical relevance J. Clin. Endocrinol. Metab. 90 2005 4503 4509
14. W. He, M.L. Wang, H.Q. Jiang, C.M. Steppan, M.E. Shin, M.C. Thurnheer, J.J. Cebra, M.A. Lazar, and G.D. Wu Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein Gastroenterology 125 2003 1388 1397
15. C.D. Hu, Y. Chinenov, and T.K. Kerppola Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation Mol. Cell 9 2002 789 798
16. A.V. Hubberstey, and E.P. Mottillo Cyclase-associated proteins: CAPacity for linking signal transduction and actin polymerization FASEB J. 16 2002 487 499
17. J. Hur, H.M. Yang, C.H. Yoon, C.S. Lee, K.W. Park, J.H. Kim, T.Y. Kim, J.Y. Kim, H.J. Kang, and I.H. Chae et al. Identification of a novel role of T cells in postnatal vasculogenesis: characterization of endothelial progenitor cell colonies Circulation 116 2007 1671 1682
18. H.S. Jung, K.H. Park, Y.M. Cho, S.S. Chung, H.J. Cho, S.Y. Cho, S.J. Kim, S.Y. Kim, H.K. Lee, and K.S. Park Resistin is secreted from macrophages in atheromas and promotes atherosclerosis Cardiovasc. Res. 69 2006 76 85
19. A. Kushiyama, H. Sakoda, N. Oue, M. Okubo, Y. Nakatsu, H. Ono, T. Fukushima, H. Kamata, F. Nishimura, and T. Kikuchi et al. Resistin-like molecule β is abundantly expressed in foam cells and is involved in atherosclerosis development Arterioscler. Thromb. Vasc. Biol. 33 2013 1986 1993
20. F.P. Li, J. He, Z.Z. Li, Z.F. Luo, L. Yan, and Y. Li Effects of resistin expression on glucose metabolism and hepatic insulin resistance Endocrine 35 2009 243 251
21. T. Lila, and D.G. Drubin Evidence for physical and functional interactions among two Saccharomyces cerevisiae SH3 domain proteins, an adenylyl cyclase-associated protein and the actin cytoskeleton Mol. Biol. Cell 8 1997 367 385
22. H. Matviw, G. Yu, and D. Young Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteins Mol. Cell. Biol. 12 1992 5033 5040
23. C.L. McTernan, P.G. McTernan, A.L. Harte, P.L. Levick, A.H. Barnett, and S. Kumar Resistin, central obesity, and type 2 diabetes Lancet 359 2002 46 47
24. M. Nakata, T. Okada, K. Ozawa, and T. Yada Resistin induces insulin resistance in pancreatic islets to impair glucose-induced insulin release Biochem. Biophys. Res. Commun. 353 2007 1046 1051
25. A.A. Noegel, F. Rivero, R. Albrecht, K.P. Janssen, J. Köhler, C.A. Parent, and M. Schleicher Assessing the role of the ASP56/CAP homologue of Dictyostelium discoideum and the requirements for subcellular localization J. Cell Sci. 112 1999 3195 3203
26. L. Patel, A.C. Buckels, I.J. Kinghorn, P.R. Murdock, J.D. Holbrook, C. Plumpton, C.H. Macphee, and S.A. Smith Resistin is expressed in human macrophages and directly regulated by PPAR gamma activators Biochem. Biophys. Res. Commun. 300 2003 472 476
27. S.D. Patel, M.W. Rajala, L. Rossetti, P.E. Scherer, and L. Shapiro Disulfide-dependent multimeric assembly of resistin family hormones Science 304 2004 1154 1158
28. M. Peters-Golden Putting on the brakes: cyclic AMP as a multipronged controller of macrophage function Sci. Signal. 2 2009 pe37
29. M. Qatanani, N.R. Szwergold, D.R. Greaves, R.S. Ahima, and M.A. Lazar Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice J. Clin. Invest. 119 2009 531 539
30. P. Raghu, S. Ghosh, K. Soundarya, A. Haseeb, B. Aruna, and N.Z. Ehtesham Dimerization of human recombinant resistin involves covalent and noncovalent interactions Biochem. Biophys. Res. Commun. 313 2004 642 646
31. M.P. Reilly, M. Lehrke, M.L. Wolfe, A. Rohatgi, M.A. Lazar, and D.J. Rader Resistin is an inflammatory marker of atherosclerosis in humans Circulation 111 2005 932 939
32. B. Sánchez-Solana, J. Laborda, and V. Baladrón Mouse resistin modulates adipogenesis and glucose uptake in 3T3-L1 preadipocytes through the ROR1 receptor Mol. Endocrinol. 26 2012 110 127
33. D.B. Savage, C.P. Sewter, E.S. Klenk, D.G. Segal, A. Vidal-Puig, R.V. Considine, and S. O'Rahilly Resistin / Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans Diabetes 50 2001 2199 2202
34. N. Silswal, A.K. Singh, B. Aruna, S. Mukhopadhyay, S. Ghosh, and N.Z. Ehtesham Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-kappaB-dependent pathway Biochem. Biophys. Res. Commun. 334 2005 1092 1101
35. C.M. Steppan, S.T. Bailey, S. Bhat, E.J. Brown, R.R. Banerjee, C.M. Wright, H.R. Patel, R.S. Ahima, and M.A. Lazar The hormone resistin links obesity to diabetes Nature 409 2001 307 312
36. M.J. Sternberg, P.A. Bates, L.A. Kelley, and R.M. MacCallum Progress in protein structure prediction: assessment of CASP3 Curr. Opin. Struct. Biol. 9 1999 368 373
37. A. Tarkowski, J. Bjersing, A. Shestakov, and M.I. Bokarewa Resistin competes with lipopolysaccharide for binding to toll-like receptor 4 J. Cell. Mol. Med. 14 6B 2010 1419 1431
38. K.M. Utzschneider, D.B. Carr, J. Tong, T.M. Wallace, R.L. Hull, S. Zraika, Q. Xiao, J.S. Mistry, B.M. Retzlaff, R.H. Knopp, and S.E. Kahn Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans Diabetologia 48 2005 2330 2333
39. A. Wakeel, J.A. Kuriakose, and J.W. McBride An Ehrlichia chaffeensis tandem repeat protein interacts with multiple host targets involved in cell signaling, transcriptional regulation, and vesicle trafficking Infect. Immun. 77 2009 1734 1745
40. E.A. Wall, J.R. Zavzavadjian, M.S. Chang, B. Randhawa, X. Zhu, R.C. Hsueh, J. Liu, A. Driver, X.R. Bao, and P.C. Sternweis et al. Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105 Sci. Signal. 2 2009 ra28
41. Y. Wu, Q. Li, and X.Z. Chen Detecting protein-protein interactions by Far western blotting Nat. Protoc. 2 2007 3278 3284
42. T. Yamauchi, J. Kamon, Y. Ito, A. Tsuchida, T. Yokomizo, S. Kita, T. Sugiyama, M. Miyagishi, K. Hara, and M. Tsunoda et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature 423 2003 762 769
43. R.Z. Yang, Q. Huang, A. Xu, J.C. McLenithan, J.A. Eisen, A.R. Shuldiner, S. Alkan, and D.W. Gong Comparative studies of resistin expression and phylogenomics in human and mouse Biochem. Biophys. Res. Commun. 310 2003 927 935
44. C.H. Yoon, J. Hur, K.W. Park, J.H. Kim, C.S. Lee, I.Y. Oh, T.Y. Kim, H.J. Cho, H.J. Kang, and I.H. Chae et al. Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases Circulation 112 2005 1618 1627
45. V. Zoete, M.B. Irving, and O. Michielin MM-GBSA binding free energy decomposition and T cell receptor engineering J. Mol. Recognit. 23 2010 142 152