Pharmacological reversion of sphingomyelin-induced dendritic spine anomalies in a Niemann Pick disease type A mouse model

EMBO Molecular Medicine

Volumn 6, Issue 3, 2014, Pages 398-413

  Arroyo, Ana I ^a   Camoletto, Paola G ^a,b   Morando, Laura ^b   Sassoe Pognetto, Marco ^b   Giustetto, Maurizio ^b   Van Veldhoven, Paul P ^c   Schuchman, Edward H ^d   Ledesma, Maria D ^a  

^a CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Dexamethasone; Niemann Pick; RhoA; Sphingomyelin

Indexed keywords

ACTIN; DEXAMETHASONE; METABOTROPIC RECEPTOR 1; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE;

ACTIN FILAMENT; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITIC SPINE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOTOR DYSFUNCTION; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SYNAPTOSOME;

ACTIN CYTOSKELETON; ANIMALS; APOPTOSIS; CELLS, CULTURED; DENDRITIC SPINES; DEXAMETHASONE; DISEASE MODELS, ANIMAL; FEMALE; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURONS; NIEMANN-PICK DISEASE, TYPE A; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS;

EID: 84895736847     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201302649     Document Type: Article

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