Differential neurodevelopmental trajectories in patients with early-onset bipolar and schizophrenia disorders

Schizophrenia Bulletin

Volumn 40, Issue SUPPL. 2, 2014, Pages

  Arango, Celso ^a,b   Fraguas, David ^a   Parellada, Mara ^a  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

cognition; differential diagnosis; neurodegeneration; neurodevelopment; neuroimaging; premorbid impairment; psychosis

Indexed keywords

ACADEMIC ACHIEVEMENT; ARTICLE; ATTENTION; BIPOLAR DISORDER; BRAIN DEVELOPMENT; CHILDHOOD DISEASE; COGNITION; COGNITIVE DEFECT; DEVELOPMENTAL DISORDER; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; ENVIRONMENTAL FACTOR; GRAY MATTER; HUMAN; INTELLIGENCE QUOTIENT; LANGUAGE DISABILITY; MOTOR PERFORMANCE; NEUROIMAGING; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIORITY JOURNAL; SCHIZOPHRENIA; SOCIAL DISABILITY; ADOLESCENT; BRAIN; CHILD; CLASSIFICATION; COMPARATIVE STUDY; CONGENITAL MALFORMATION; DIFFERENTIAL DIAGNOSIS; PATHOLOGY; PATHOPHYSIOLOGY;

ADOLESCENT; AGE OF ONSET; BIPOLAR DISORDER; BRAIN; CHILD; DEVELOPMENTAL DISABILITIES; DIAGNOSIS, DIFFERENTIAL; HUMANS; SCHIZOPHRENIA;

EID: 84895733991     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbt198     Document Type: Article

References (98)

1. Murray RM, Lewis SW. Is schizophrenia a neurodevelopmental disorder? Br Med J (Clin Res Ed). 1987;295:681-682.
2. Weinberger DR. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry. 1987;44:660-669.
3. Strauss JS, Carpenter WTJ. Schizophrenia. New York: Plenum Press; 1981.
4. Feinberg I. Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? J Psychiatr Res. 1982;17:319-334.
5. Andreasen NC. The lifetime trajectory of schizophrenia and the concept of neurodevelopment. Dialogues Clin Neurosci. 2010;12:409-415.
6. Lam CW, Berrios GE. Psychological concepts and psychiatric symptomatology in some ancient Chinese medical texts. Hist Psychiatry. 1992;3:117-128.
7. Welham JL, Thomis RJ, McGrath JJ. Age-at-first-registration for affective psychosis and schizophrenia. Schizophr Bull. 2004;30:849-853.
8. Perlis RH, Delbello MP, Miyahara S, Wisniewski SR, Sachs GS, Nierenberg AA; STEP-BD investigators. Revisiting depressive-prone bipolar disorder: polarity of initial mood episode and disease course among bipolar I systematic treatment enhancement program for bipolar disorder participants. Biol Psychiatry. 2005;58:549-553.
9. Schaffer A, Cairney J, Cheung A, Veldhuizen S, Levitt A. Community survey of bipolar disorder in Canada: lifetime prevalence and illness characteristics. Can J Psychiatry. 2006;51:9-16.
10. Berk M, Dodd S, Callaly P, et al. History of illness prior to a diagnosis of bipolar disorder or schizoaffective disorder. J Affect Disord. 2007;103:181-186.
11. Catts VS, Fung SJ, Long LE, et al. Rethinking schizophrenia in the context of normal neurodevelopment. Front Cell Neurosci. 2013;7:60.
12. Insel TR. Rethinking schizophrenia. Nature. 2010;468: 187-193.
13. Zipursky RB, Reilly TJ, Murray RM. The myth of schizophrenia as a progressive brain disease. Schizophr Bull. 2013;39:1363-1372.
14. Rapoport JL, Giedd JN, Gogtay N. Neurodevelopmental model of schizophrenia: update 2012. Mol Psychiatry. 2012;17:1228-1238.
15. Matheson SL, Shepherd AM, Laurens KR, Carr VJ. A systematic meta-review grading the evidence for non-genetic risk factors and putative antecedents of schizophrenia. Schizophr Res. 2011;133:133-142.
16. Goldstein JM, Seidman LJ, Buka SL, et al. Impact of genetic vulnerability and hypoxia on overall intelligence by age 7 in offspring at high risk for schizophrenia compared with affective psychoses. Schizophr Bull. 2000;26:323-334.
17. MacCabe JH, Lambe MP, Cnattingius S, et al. Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study. Br J Psychiatry. 2010;196:109-115.
18. MacCabe JH, Lambe MP, Cnattingius S, et al. Scholastic achievement at age 16 and risk of schizophrenia and other psychoses: a national cohort study. Psychol Med. 2008;38:1133-1140.
19. Cannon M, Caspi A, Moffitt TE, et al. Evidence for earlychildhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohort. Arch Gen Psychiatry. 2002;59:449-456.
20. Koenen KC, Moffitt TE, Roberts AL, et al. Childhood IQ and adult mental disorders: a test of the cognitive reserve hypothesis. Am J Psychiatry. 2009;166:50-57.
21. Horwood J, Salvi G, Thomas K, et al. IQ and non- clinical psychotic symptoms in 12-year-olds: results from the ALSPAC birth cohort. Br J Psychiatry. 2008;193:185-191.
22. Zanelli J, Reichenberg A, Morgan K, et al. Specific and generalized neuropsychological deficits: a comparison of patients with various first-episode psychosis presentations. Am J Psychiatry. 2010;167:78-85.
23. Bombin I, Mayoral M, Castro-Fornieles J, et al. Neuropsychological evidence for abnormal neurodevelopment associated with early-onset psychoses. Psychol Med. 2013;43:757-768.
24. Zabala A, Rapado M, Arango C, et al. Neuropsychological functioning in early-onset first-episode psychosis: comparison of diagnostic subgroups. Eur Arch Psychiatry Clin Neurosci. 2010;260:225-233.
25. Haijma SV, Van Haren N, Cahn W, Koolschijn PC, Hulshoff Pol HE, Kahn RS. Brain volumes in schizophrenia: a meta-analysis in over 18 000 subjects. Schizophr Bull. 2013;39:1129-1138.
26. Fusar-Poli P, Smieskova R, Kempton MJ, Ho BC, Andreasen NC, Borgwardt S. Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies. Neurosci Biobehav Rev. 2013;37:1680-1691.
27. Pompei F, Jogia J, Tatarelli R, et al. Familial and disease specific abnormalities in the neural correlates of the Stroop Task in Bipolar Disorder. Neuroimage. 2011;56:1677-1684.
28. Skudlarski P, Schretlen DJ, Thaker GK, et al. Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives. Am J Psychiatry. 2013;170:886-898.
29. Parellada M. Markers of deviant development in early onset psychosis. With special reference to schizophrenia [European Doctorate]. Alcalá: Alcalá de Henares; 2006.
30. Zhao Q, Ma YT, Lui SS, et al. Neurological soft signs discriminate schizophrenia from major depression but not bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2013;43:72-78.
31. Whitty P, Clarke M, McTigue O, et al. Diagnostic specificity and predictors of neurological soft signs in schizophrenia, bipolar disorder and other psychoses over the first 4 years of illness. Schizophr Res. 2006;86:110-117.
32. Tamagni C, Studerus E, Gschwandtner U, Aston J, Borgwardt S, Riecher-Rössler A. Are neurological soft signs pre-existing markers in individuals with an at-risk mental state for psychosis? Psychiatry Res. 2013;210:427-431.
33. Mayoral M, Bombín I, Castro-Fornieles J, et al. Longitudinal study of neurological soft signs in first-episode early-onset psychosis. J Child Psychol Psychiatry. 2012;53:323-331.
34. Walker E, Lewine RJ. Prediction of adult-onset schizophrenia from childhood home movies of the patients. Am J Psychiatry. 1990;147:1052-1056.
35. Hollis C. Child and adolescent (juvenile onset) schizophrenia. A case control study of premorbid developmental impairments. Br J Psychiatry. 1995;166:489-495.
36. Larsen TK, McGlashan TH, Johannessen JO, Vibe-Hansen L. First-episode schizophrenia: II. Premorbid patterns by gender. Schizophr Bull. 1996;22:257-269.
37. Larsen TK, McGlashan TH, Moe LC. First-episode schizophrenia: I. Early course parameters. Schizophr Bull. 1996;22:241-256.
38. Malmberg A, Lewis G, David A, Allebeck P. Premorbid adjustment and personality in people with schizophrenia. Br J Psychiatry. 1998;172:308-313.
39. Schmael C, Georgi A, Krumm B, et al. Premorbid adjustment in schizophrenia-an important aspect of phenotype definition. Schizophr Res. 2007;92:50-62.
40. Alaghband-Rad J, McKenna K, Gordon CT, et al. Childhoodonset schizophrenia: the severity of premorbid course. J Am Acad Child Adolesc Psychiatry. 1995;34:1273-1283.
41. van Os J, Jones P, Lewis G, Wadsworth M, Murray R. Developmental precursors of affective illness in a general population birth cohort. Arch Gen Psychiatry. 1997;54:625-631.
42. Sigurdsson E, Fombonne E, Sayal K, Checkley S. Neurodevelopmental antecedents of early-onset bipolar affective disorder. Br J Psychiatry. 1999;174:121-127.
43. Maynard TM, Sikich L, Lieberman JA, LaMantia AS. Neural development, cell-cell signaling, and the "two-hit" hypothesis of schizophrenia. Schizophr Bull. 2001;27:457-476.
44. Reichenberg A, Weiser M, Rabinowitz J, et al. A populationbased cohort study of premorbid intellectual, language, and behavioral functioning in patients with schizophrenia, schizoaffective disorder, and nonpsychotic bipolar disorder. Am J Psychiatry. 2002;159:2027-2035.
45. Zammit S, Allebeck P, David AS, et al. A longitudinal study of premorbid IQ Score and risk of developing schizophrenia, bipolar disorder, severe depression, and other nonaffective psychoses. Arch Gen Psychiatry. 2004;61:354-360.
46. Kutcher S, Robertson HA, Bird D. Premorbid functioning in adolescent onset bipolar I disorder: a preliminary report from an ongoing study. J Affect Disord. 1998;51:137-144.
47. Goldberg JF, Ernst CL. Clinical correlates of childhood and adolescent adjustment in adult patients with bipolar disorder. J Nerv Ment Dis. 2004;192:187-192.
48. Haim R, Rabinowitz J, Bromet E. The relationship of premorbid functioning to illness course in schizophrenia and psychotic mood disorders during two years following first hospitalization. J Nerv Ment Dis. 2006;194:791-795.
49. Vocisano C, Klein DN, Keefe RS, Dienst ER, Kincaid MM. Demographics, family history, premorbid functioning, developmental characteristics, and course of patients with deteriorated affective disorder. Am J Psychiatry. 1996;153:248-255.
50. Payá B, Rodríguez-Sánchez JM, Otero S, et al. Premorbid impairments in early-onset psychosis: differences between patients with schizophrenia and bipolar disorder. Schizophr Res. 2013;146:103-110.
51. Arango C, Moreno C, Martínez S, et al. Longitudinal brain changes in early-onset psychosis. Schizophr Bull. 2008;34:341-353.
52. Arango C, Rapado-Castro M, Reig S, et al. Progressive brain changes in children and adolescents with first-episode psychosis. Arch Gen Psychiatry. 2012;69:16-26.
53. Mechelli A, Riecher-Rössler A, Meisenzahl EM, et al. Neuroanatomical abnormalities that predate the onset of psychosis: a multicenter study. Arch Gen Psychiatry. 2011;68:489-495.
54. Pantelis C, Velakoulis D, McGorry PD, et al. Neuroanatomical abnormalities before and after onset of psychosis: a crosssectional and longitudinal MRI comparison. Lancet. 2003;361:281-288.
55. Gogtay N. Cortical brain development in schizophrenia: insights from neuroimaging studies in childhood-onset schizophrenia. Schizophr Bull. 2008;34:30-36.
56. Greenstein D, Lerch J, Shaw P, et al. Childhood onset schizophrenia: cortical brain abnormalities as young adults. J Child Psychol Psychiatry. 2006;47:1003-1012.
57. Gogtay N, Rapoport JL. Childhood-onset schizophrenia: insights from neuroimaging studies. J Am Acad Child Adolesc Psychiatry. 2008;47:1120-1124.
58. Giedd JN, Rapoport JL. Structural MRI of pediatric brain development: what have we learned and where are we going? Neuron. 2010;67:728-734.
59. Gogtay N, Greenstein D, Lenane M, et al. Cortical brain development in nonpsychotic siblings of patients with childhood-onset schizophrenia. Arch Gen Psychiatry. 2007;64:772-780.
60. Mattai AA, Weisinger B, Greenstein D, et al. Normalization of cortical gray matter deficits in nonpsychotic siblings of patients with childhood-onset schizophrenia. J Am Acad Child Adolesc Psychiatry. 2011;50:697-704.
61. Arnone D, Cavanagh J, Gerber D, Lawrie SM, Ebmeier KP, McIntosh AM. Magnetic resonance imaging studies in bipolar disorder and schizophrenia: Meta-analysis. Br J Psychiatry. 2009;195:194-201.
62. McDonald C, Marshall N, Sham PC, et al. Regional brain morphometry in patients with schizophrenia or bipolar disorder and their unaffected relatives. Am J Psychiatry. 2006;163:478-487.
63. Kempton MJ, Geddes JR, Ettinger U, Williams SC, Grasby PM. Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder. Arch Gen Psychiatry. 2008;65:1017-1032.
64. Ellison-Wright I, Bullmore E. Anatomy of bipolar disorder and schizophrenia: a meta-analysis. Schizophr Res. 2010;117:1-12.
65. Hulshoff Pol HE, van Baal GC, Schnack HG, et al. Overlapping and segregating structural brain abnormalities in twins with schizophrenia or bipolar disorder. Arch Gen Psychiatry. 2012;69:349-359.
66. Friedman L, Findling RL, Kenny JT, et al. An MRI study of adolescent patients with either schizophrenia or bipolar disorder as compared to healthy control subjects. Biol Psychiatry. 1999;46:78-88.
67. Janssen J, Reig S, Parellada M, et al. Regional gray matter volume deficits in adolescents with first-episode psychosis. J Am Acad Child Adolesc Psychiatry. 2008;47:1311-1320.
68. El-Sayed M, Steen RG, Poe MD, et al. Brain volumes in psychotic youth with schizophrenia and mood disorders. J Psychiatry Neurosci. 2010;35:229-236.
69. Reig S, Moreno C, Moreno D, et al. Progression of brain volume changes in adolescent-onset psychosis. Schizophr Bull. 2009;35:233-243.
70. Janssen J, Diaz-Caneja A, Reig S, et al. Brain morphology and neurological soft signs in adolescents with first-episode psychosis. Br J Psychiatry. 2009;195:227-233.
71. Reig S, Parellada M, Castro-Fornieles J, et al. Multicenter study of brain volume abnormalities in children and adolescent- onset psychosis. Schizophr Bull. 2011;37:1270-1280.
72. Gogtay N, Sporn A, Clasen LS, et al. Comparison of progressive cortical gray matter loss in childhood-onset schizophrenia with that in childhood-onset atypical psychoses. Arch Gen Psychiatry. 2004;61:17-22.
73. Gogtay N, Weisinger B, Bakalar JL, et al. Psychotic symptoms and gray matter deficits in clinical pediatric populations. Schizophr Res. 2012;140:149-154.
74. Micó JA, Rojas-Corrales MO, Gibert-Rahola J, et al. Reduced antioxidant defense in early onset first-episode psychosis: a case-control study. BMC Psychiatry. 2011;11:26.
75. de la Serna E, Andres-Perpina S, Puig O, et al. Cognitive reserve as a predictor of two year neuropsychological performance in early onset first-episode schizophrenia. Schizophr Res. 2013;143:125-131.
76. Demjaha A, MacCabe JH, Murray RM. How genes and environmental factors determine the different neurodevelopmental trajectories of schizophrenia and bipolar disorder. Schizophr Bull. 2012;38:209-214.
77. Owoeye O, Kingston T, Scully PJ, et al. Epidemiological and clinical characterization following a first psychotic episode in major depressive disorder: comparisons with schizophrenia and bipolar I disorder in the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS). Schizophr Bull. 2013;39:756-765.
78. Hiroi N, Takahashi T, Hishimoto A, Izumi T, Boku S, Hiramoto T. Copy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders. Mol Psychiatry. 2013;18:1153-1165.
79. Owen MJ, Craddock N, Jablensky A. The genetic deconstruction of psychosis. Schizophr Bull. 2007;33:905-911.
80. Purcell SM, Wray NR, Stone JL, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460:748-752.
81. Smoller JW, Craddock N, Kendler K, et al. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381:1371-1379.
82. Karege F, Méary A, Perroud N, et al. Genetic overlap between schizophrenia and bipolar disorder: a study with AKT1 gene variants and clinical phenotypes. Schizophr Res. 2012;135:8-14.
83. Thaker GK. Boundaries of the psychosis phenotype. Schizophr Bull. 2012;38:205-206.
84. Fraguas D, Gonzalez-Pinto A, Micó JA, et al. Decreased glutathione levels predict loss of brain volume in children and adolescents with first-episode psychosis in a two-year longitudinal study. Schizophr Res. 2012;137:58-65.
85. Parellada M, Boada L, Fraguas D, et al. Trait and state attributes of insight in first episodes of early-onset schizophrenia and other psychoses: a 2-year longitudinal study. Schizophr Bull. 2011;37:38-51.
86. Matheson SL, Shepherd AM, Pinchbeck RM, Laurens KR, Carr VJ. Childhood adversity in schizophrenia: a systematic meta-analysis. Psychol Med. 2013;43:225-238.
87. McGrath J, Welham J, Scott J, et al. Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults. Arch Gen Psychiatry. 2010;67:440-447.
88. Moore TH, Zammit S, Lingford-Hughes A, et al. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet. 2007;370:319-328.
89. Lagerberg TV, Sundet K, Aminoff SR, et al. Excessive cannabis use is associated with earlier age at onset in bipolar disorder. Eur Arch Psychiatry Clin Neurosci. 2011;261:397-405.
90. Tijssen MJ, Van Os J, Wittchen HU, Lieb R, Beesdo K, Wichers M. Risk factors predicting onset and persistence of subthreshold expression of bipolar psychopathology among youth from the community. Acta Psychiatr Scand. 2010;122:255-266.
91. Piper M, Beneyto M, Burne TH, Eyles DW, Lewis DA, McGrath JJ. The neurodevelopmental hypothesis of schizophrenia: convergent clues from epidemiology and neuropathology. Psychiatr Clin North Am. 2012;35:571-584.
92. Haukvik UK, McNeil T, Lange EH, et al. Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder. Psychol Med. 2013;27:1-11. PMID: 23803260.
93. Martelon M, Wilens TE, Anderson JP, Morrison NR, Wozniak J. Are obstetrical, perinatal, and infantile difficulties associated with pediatric bipolar disorder? Bipolar Disord. 2012;14:507-514.
94. Scott J, McNeill Y, Cavanagh J, Cannon M, Murray R. Exposure to obstetric complications and subsequent development of bipolar disorder: systematic review. Br J Psychiatry. 2006;189:3-11.
95. Cantor-Graae E, Selten JP. Schizophrenia and migration: a meta-analysis and review. Am J Psychiatry. 2005;162:12-24.
96. Swinnen SG, Selten JP. Mood disorders and migration: Metaanalysis. Br J Psychiatry. 2007;190:6-10.
97. Kelly BD, O'Callaghan E, Waddington JL, et al. Schizophrenia and the city: a review of literature and prospective study of psychosis and urbanicity in Ireland. Schizophr Res. 2010;116:75-89.
98. Hill SK, Reilly JL, Keefe RS, et al. Neuropsychological Impairments in Schizophrenia and Psychotic Bipolar Disorder: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) Study. Am J Psychiatry. 2013;170:1275-1284.