The regulation of alfalfa saponin extract on key genes involved in hepatic cholesterol metabolism in hyperlipidemic rats

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Shi, Yinghua ^a   Guo, Rui ^a   Wang, Xianke ^a   Yuan, Dedi ^a   Zhang, Senhao ^a   Wang, Jie ^a   Yan, Xuebing ^a   Wang, Chengzhang ^a  

^a HENAN AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALFALFA EXTRACT; BILE ACID; CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT; MESSENGER RNA; PLANT EXTRACT; SAPONIN; UNCLASSIFIED DRUG;

ACAT2 GENE; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE ACID BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; CYP7A1 GENE; DOWN REGULATION; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVITY; FECES ANALYSIS; GENE; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HMGCR GENE; HYPERLIPIDEMIA; LDLR GENE; LIVER WEIGHT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYTOCHEMISTRY; RAT; TREATMENT DURATION; UPREGULATION; WEIGHT GAIN;

ANIMALS; BILE ACIDS AND SALTS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; GENE EXPRESSION REGULATION; HYPERLIPIDEMIAS; LIPID METABOLISM; LIVER; MALE; MEDICAGO SATIVA; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SAPONINS; TRIGLYCERIDES;

EID: 84895530498     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088282     Document Type: Article

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