메뉴 건너뛰기




Volumn 4, Issue 2, 2014, Pages

Interference with pre-B-cell receptor signaling offers a therapeutic option for TCF3-rearranged childhood acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BRUTON TYROSINE KINASE; IBRUTINIB; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; INTERFERON REGULATORY FACTOR 4; PHOSPHATIDYLINOSITOL 3 KINASE P110 DELTA; PLC GAMMA 2 PROTEIN; PRE B CELL RECEPTOR; PROTEIN KINASE LYN; PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; SLP65 PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 1; UNCLASSIFIED DRUG;

EID: 84895452149     PISSN: None     EISSN: 20445385     Source Type: Journal    
DOI: 10.1038/bcj.2014.5     Document Type: Letter
Times cited : (19)

References (23)
  • 1
    • 79952078495 scopus 로고    scopus 로고
    • Biology, risk stratification, and therapy of pediatric acute leukemias: An update
    • Pui CH, Carroll WL, Meshinchi S, Arceci RJ. Biology, risk stratification, and therapy of pediatric acute leukemias: an update. J Clin oncol 2011; 29: 551-565.
    • (2011) J Clin Oncol , vol.29 , pp. 551-565
    • Pui, C.H.1    Carroll, W.L.2    Meshinchi, S.3    Arceci, R.J.4
  • 2
    • 33947382184 scopus 로고    scopus 로고
    • Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B-cell precursor acute lymphoblastic leukemia
    • Barber KE, Harrison CJ, Broadfield ZJ, Stewart AR, Wright SL, Martineau M et al. Molecular cytogenetic characterization of TCF3 (E2A)/19p13.3 rearrangements in B-cell precursor acute lymphoblastic leukemia. Genes Chromosomes Cancer 2007; 46: 478-486.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 478-486
    • Barber, K.E.1    Harrison, C.J.2    Broadfield, Z.J.3    Stewart, A.R.4    Wright, S.L.5    Martineau, M.6
  • 3
    • 0021330533 scopus 로고
    • New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia
    • Williams DL, Look AT, Melvin SL, Roberson PK, Dahl G, Flake T et al. New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia. Cell 1984; 36: 101-109.
    • (1984) Cell , vol.36 , pp. 101-109
    • Williams, D.L.1    Look, A.T.2    Melvin, S.L.3    Roberson, P.K.4    Dahl, G.5    Flake, T.6
  • 4
    • 0025328804 scopus 로고
    • Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): A Pediatric Oncology Group study
    • Crist WM, Carroll AJ, Shuster JJ, Behm FG, Whitehead M, Vietti TJ et al. Poor prognosis of children with pre-B acute lymphoblastic leukemia is associated with the t(1;19)(q23;p13): a Pediatric Oncology Group study. Blood 1990; 76: 117-122.
    • (1990) Blood , vol.76 , pp. 117-122
    • Crist, W.M.1    Carroll, A.J.2    Shuster, J.J.3    Behm, F.G.4    Whitehead, M.5    Vietti, T.J.6
  • 5
    • 0023035608 scopus 로고
    • Lambda 5, a new light-chain-related locus selectively expressed in pre-B lymphocytes
    • Sakaguchi N, Melchers F. Lambda 5, a new light-chain-related locus selectively expressed in pre-B lymphocytes. Nature 1986; 324: 579-582.
    • (1986) Nature , vol.324 , pp. 579-582
    • Sakaguchi, N.1    Melchers, F.2
  • 6
    • 61349179407 scopus 로고    scopus 로고
    • Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling
    • Herzog S, Reth M, Jumaa H. Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nat Rev Immunol 2009; 9: 195-205.
    • (2009) Nat Rev Immunol , vol.9 , pp. 195-205
    • Herzog, S.1    Reth, M.2    Jumaa, H.3
  • 7
    • 44649186791 scopus 로고    scopus 로고
    • Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development
    • Kwon K, Hutter C, Sun Q, Bilic I, Cobaleda C, Malin S et al. Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development. Immunity 2008; 28: 751-762.
    • (2008) Immunity , vol.28 , pp. 751-762
    • Kwon, K.1    Hutter, C.2    Sun, Q.3    Bilic, I.4    Cobaleda, C.5    Malin, S.6
  • 8
    • 0035839891 scopus 로고    scopus 로고
    • The role of E2A-PBX1 in leukemogenesis
    • Aspland SE, Bendall HH, Murre C. The role of E2A-PBX1 in leukemogenesis. Oncogene 2001; 20: 5708-5717.
    • (2001) Oncogene , vol.20 , pp. 5708-5717
    • Aspland, S.E.1    Bendall, H.H.2    Murre, C.3
  • 9
    • 65649143517 scopus 로고    scopus 로고
    • MRD detection in acute lymphoblastic leukemia patients using Ig/TCR gene rearrangements as targets for real-time quantitative PCR
    • van der Velden VH, van Dongen JJ. MRD detection in acute lymphoblastic leukemia patients using Ig/TCR gene rearrangements as targets for real-time quantitative PCR. Methods Mol Biol 2009; 538: 115-150.
    • (2009) Methods Mol Biol , vol.538 , pp. 115-150
    • Van Der-Velden, V.H.1    Van Dongen, J.J.2
  • 10
    • 34248216623 scopus 로고    scopus 로고
    • Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival
    • Petricoin EF, Espina V, Araujo RP, Midura B, Yeung C, Wan X et al. Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res 2007; 67: 3431-3440.
    • (2007) Cancer Res , vol.67 , pp. 3431-3440
    • Petricoin, E.F.1    Espina, V.2    Araujo, R.P.3    Midura, B.4    Yeung, C.5    Wan, X.6
  • 11
    • 84871806385 scopus 로고    scopus 로고
    • Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies
    • Advani RH, Buggy JJ, Sharman JP, Smith SM, Boyd TE, Grant B et al. Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B-cell malignancies. J Clin Oncol 2013; 31: 88-94.
    • (2013) J Clin Oncol , vol.31 , pp. 88-94
    • Advani, R.H.1    Buggy, J.J.2    Sharman, J.P.3    Smith, S.M.4    Boyd, T.E.5    Grant, B.6
  • 12
    • 84863011553 scopus 로고    scopus 로고
    • The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
    • Ponader S, Chen SS, Buggy JJ, Balakrishnan K, Gandhi V, Wierda WG et al. The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood 2012; 119: 1182-1189.
    • (2012) Blood , vol.119 , pp. 1182-1189
    • Ponader, S.1    Chen, S.S.2    Buggy, J.J.3    Balakrishnan, K.4    Gandhi, V.5    Wierda, W.G.6
  • 13
    • 84867589196 scopus 로고    scopus 로고
    • BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-kappaB
    • Rushworth SA, Bowles KM, Barrera LN, Murray MY, Zaitseva L, Macewan DJ. BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-kappaB. Cell Signal 2012; 25: 106-114.
    • (2012) Cell Signal , vol.25 , pp. 106-114
    • Rushworth, S.A.1    Bowles, K.M.2    Barrera, L.N.3    Murray, M.Y.4    Zaitseva, L.5    MacEwan, D.J.6
  • 14
    • 0141799965 scopus 로고    scopus 로고
    • Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia
    • Den Boer ML, Harms DO, Pieters R, Kazemier KM, Göbel U, Körholz D et al. Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia. J Clin Oncol 2003; 21: 3262-3268.
    • (2003) J Clin Oncol , vol.21 , pp. 3262-3268
    • Den Boer, M.L.1    Harms, D.O.2    Pieters, R.3    Kazemier, K.M.4    Göbel, U.5    Körholz, D.6
  • 15
    • 79959404661 scopus 로고    scopus 로고
    • Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
    • Herman SE, Gordon AL, Hertlein E, Ramanunni A, Zhang X, Jaglowski S et al. Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765. Blood 2011; 117: 6287-6296.
    • (2011) Blood , vol.117 , pp. 6287-6296
    • Herman, S.E.1    Gordon, A.L.2    Hertlein, E.3    Ramanunni, A.4    Zhang, X.5    Jaglowski, S.6
  • 17
    • 84887608390 scopus 로고    scopus 로고
    • Activity of Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (PCI-32765) in B-cell acute lymphoblastic leukemia (B-ALL)
    • Kim E, Koehrer S, Rosin NY, Thomas DA, Ravandi F, Kornblau SM et al. Activity of Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (PCI-32765) in B-cell acute lymphoblastic leukemia (B-ALL). ASH Annual Meeting Abstracts 2012; 120: 2569.
    • (2012) ASH Annual Meeting Abstracts , vol.120 , pp. 2569
    • Kim, E.1    Koehrer, S.2    Rosin, N.Y.3    Thomas, D.A.4    Ravandi, F.5    Kornblau, S.M.6
  • 18
    • 84887695622 scopus 로고    scopus 로고
    • Egress of CD19(+)CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients
    • Chang BY, Francesco M, De Rooij MF, Magadala P, Steggerda SM, Huang MM et al. Egress of CD19(+)CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients. Blood 2013; 122: 2412-2424.
    • (2013) Blood , vol.122 , pp. 2412-2424
    • Chang, B.Y.1    Francesco, M.2    De Rooij, M.F.3    Magadala, P.4    Steggerda, S.M.5    Huang, M.M.6
  • 19
    • 84858636448 scopus 로고    scopus 로고
    • The clinically active BTK inhibitor PCI-32765 targets B-cell receptor-and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
    • de Rooij MF, Kuil A, Geest CR, Eldering E, Chang BY, Buggy JJ et al. The clinically active BTK inhibitor PCI-32765 targets B-cell receptor-and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia. Blood 2012; 119: 2590-2594.
    • (2012) Blood , vol.119 , pp. 2590-2594
    • De Rooij, M.F.1    Kuil, A.2    Geest, C.R.3    Eldering, E.4    Chang, B.Y.5    Buggy, J.J.6
  • 20
    • 33751567260 scopus 로고    scopus 로고
    • IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development
    • Ma S, Turetsky A, Trinh L, Lu R. IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development. J Immunol 2006; 177: 7898-7904.
    • (2006) J Immunol , vol.177 , pp. 7898-7904
    • Ma, S.1    Turetsky, A.2    Trinh, L.3    Lu, R.4
  • 21
    • 84862626662 scopus 로고    scopus 로고
    • Negative feedback regulation of antigen receptors through calmodulin inhibition of E2A
    • Verma-Gaur J, Hauser J, Grundstrom T. Negative feedback regulation of antigen receptors through calmodulin inhibition of E2A. J Immunol 2012; 188: 6175-6183.
    • (2012) J Immunol , vol.188 , pp. 6175-6183
    • Verma-Gaur, J.1    Hauser, J.2    Grundstrom, T.3
  • 22
    • 77952305440 scopus 로고    scopus 로고
    • Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: Results from the UK Medical Research Council ALL97/99 randomised trial
    • Moorman AV, Ensor HM, Richards SM, Chilton L, Schwab C, Kinsey SE et al. Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. Lancet Oncol 2010; 11: 429-438.
    • (2010) Lancet Oncol , vol.11 , pp. 429-438
    • Moorman, A.V.1    Ensor, H.M.2    Richards, S.M.3    Chilton, L.4    Schwab, C.5    Kinsey, S.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.