A multicenter cross-sectional study of circulating soluble urokinase receptor in Japanese patients with glomerular disease

Kidney International

Volumn 85, Issue 3, 2014, Pages 641-648

  Wada, Takehiko ^a   Nangaku, Masaomi ^a   Maruyama, Shoichi ^b   Imai, Enyu ^c   Shoji, Kumi ^a   Kato, Sawako ^b   Endo, Tomomi ^d   Muso, Eri ^d   Kamata, Kouju ^e   Yokoyama, Hitoshi ^f   Fujimoto, Keiji ^f   Obata, Yoko ^g   Nishino, Tomoya ^g   Kato, Hideki ^h   Uchida, Shunya ^h   Sasatomi, Yoshie ⁱ   Saito, Takao ⁱ   Matsuo, Seiichi ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Nakayamadera Imai Clinic   (Japan)

^d Kitano Hospital   (Japan)

^e KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f KANAZAWA MEDICAL UNIVERSITY   (Japan)

^g NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^h TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ANCA; diagnosis; focal segmental glomerulosclerosis; glomerular disease; nephrotic syndrome

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; CHOLESTEROL; IMMUNOSUPPRESSIVE AGENT; NEUTROPHIL CYTOPLASMIC ANTIBODY; STEROID; UROKINASE RECEPTOR;

ADOLESCENT; ADULT; AGE; AGED; ALBUMIN BLOOD LEVEL; AREA UNDER THE CURVE; ARTICLE; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATIONAL STUDY; CROSS-SECTIONAL STUDY; DIAGNOSTIC VALUE; DISEASE MARKER; FEMALE; FOCAL GLOMERULOSCLEROSIS; GLOMERULONEPHRITIS; GLOMERULOPATHY; GLOMERULUS FILTRATION RATE; HUMAN; INFLAMMATION; JAPANESE; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MEMBRANOUS GLOMERULONEPHRITIS; MINIMAL CHANGE DISEASE; MULTICENTER STUDY; MULTIPLE REGRESSION; PRIORITY JOURNAL; PROTEIN URINE LEVEL; RECEIVER OPERATING CHARACTERISTIC; URINARY EXCRETION; VERY ELDERLY; ANCA ASSOCIATED GLOMERULONEPHRITIS; DIFFERENTIAL DIAGNOSIS; IMMUNOGLOBULIN A NEPHROPATHY; JAPANESE (PEOPLE); MINIMAL CHANGE GLOMERULONEPHRITIS; PROTEIN BLOOD LEVEL; PROTEINURIA; BLOOD; CLINICAL TRIAL; LIPOID NEPHROSIS; MIDDLE AGED;

ADULT; AGED; C-REACTIVE PROTEIN; CROSS-SECTIONAL STUDIES; FEMALE; GLOMERULAR FILTRATION RATE; GLOMERULONEPHRITIS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; MALE; MIDDLE AGED; NEPHROSIS, LIPOID; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR;

EID: 84895114740     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.544     Document Type: Article

References (26)

1. D'Agati VD, Kaskel FJ, Falk RJ. Focal segmental glomerulosclerosis. N Engl J Med 2011; 365: 2398-2411
2. Hoyer JR, Vernier RL, Najarian JS et al. Recurrence of idiopathic nephrotic syndrome after renal transplantation. 1972. J Am Soc Nephrol 2001; 12: 1994-2002
3. Chang JW, Pardo V, Sageshima J et al. Podocyte foot process effacement in postreperfusion allograft biopsies correlates with early recurrence of proteinuria in focal segmental glomerulosclerosis. Transplantation 2012; 93: 1238-1244
4. Artero ML, Sharma R, Savin VJ et al. Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis. Am J Kidney Dis 1994; 23: 574-581
5. Deegens JK, Andresdottir MB, Croockewit S et al. Plasma exchange improves graft survival in patients with recurrent focal glomerulosclerosis after renal transplant. Transpl Int 2004; 17: 151-157
6. Haas M, Godfrin Y, Oberbauer R et al. Plasma immunadsorption treatment in patients with primary focal and segmental glomerulosclerosis. Nephrol Dial Transplant 1998; 13: 2013-2016
7. Muso E, Mune M, Yorioka N et al. Beneficial effect of low-density lipoprotein apheresis (LDL-A) on refractory nephrotic syndrome (NS) due to focal glomerulosclerosis (FGS). Clin Nephrol 2007; 67: 341-344
8. Kemper MJ, Wolf G, Muller-Wiefel DE. Transmission of glomerular permeability factor from a mother to her child. N Engl J Med 2001; 344: 386-387
9. Gallon L, Leventhal J, Skaro A et al. Resolution of recurrent focal segmental glomerulosclerosis after retransplantation. N Engl J Med 2012; 366: 1648-1649
10. Wei C, El Hindi S, Li J et al. Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med 2011; 17: 952-960
11. Wei C, Moller CC, Altintas MM et al. Modification of kidney barrier function by the urokinase receptor. Nat Med 2008; 14: 55-63
12. Wei C, Trachtman H, Li J et al. Circulating suPAR in two cohorts of primary FSGS. J Am Soc Nephrol 2012; 23: 2051-2059
13. Maas RJ, Wetzels JF, Deegens JK. Serum-soluble urokinase receptor concentration in primary FSGS. Kidney Int 2012; 81: 1043-1044
14. Trachtman H, Gipson DS, Kaskel F et al. Regarding Maas's editorial letter on serum suPAR levels. Kidney Int 2012; 82: 492
15. Maas RJ, Deegens JK, Wetzels JF. Serum suPAR in patients with FSGS: trash or treasure? Pediatr Nephrol 2013; 28: 1041-1048
16. Jefferson JA, Shankland SJ. Has the circulating permeability factor in primary FSGS been found? Kidney Int 2013; 84: 235-238
17. Huang J, Liu G, Zhang YM et al. Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int 2013; 84: 366-372
18. Bock ME, Price HE, Gallon L et al. Serum soluble urokinase-type plasminogen activator receptor levels and idiopathic FSGS in children: a single-center report. Clin J Am Soc Nephrol 2013; 8: 1304-1311
19. Japanese Society of Nephrology. Guidelines for the treatment of nephrotic syndrome. Nihon Jinzo Gakkai Shi 2011; 53: 78-122
20. Koch A, Voigt S, Kruschinski C et al. Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients. Crit Care 2011; 15: R63
21. Yilmaz G, Koksal I, Karahan SC et al. The diagnostic and prognostic significance of soluble urokinase plasminogen activator receptor in systemic inflammatory response syndrome. Clin Biochem 2011; 44: 1227-1230
22. Backes Y, van der Sluijs KF, Mackie DP et al. Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review. Intens Care Med 2012; 38: 1418-1428
23. Pawlak K, Ulazka B, Mysliwiec M et al. Vascular endothelial growth factor and uPA/suPAR system in early and advanced chronic kidney disease patients: a new link between angiogenesis and hyperfibrinolysis? Transl Res 2012; 160: 346-354
24. Roelofs JJ, Rouschop KM, Teske GJ et al. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis. Kidney Int 2006; 70: 1942-1947
25. Garin EH, Mu W, Arthur JM et al. Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis. Kidney Int 2010; 78: 296-302
26. Matsuo S, Imai E, Horio M et al. Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 2009; 53: 982-992.