The diagnostic and prognostic significance of soluble urokinase plasminogen activator receptor in systemic inflammatory response syndrome

Clinical Biochemistry

Volumn 44, Issue 14-15, 2011, Pages 1227-1230

  Yilmaz, Gürdal ^a   Köksal, Iftihar ^a   Karahan, S Caner ^a   Mentese, Ahmet ^a  

^a KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

Author keywords

C reactive protein; Plasminogen activators; Procalcitonin; SuPAR; Systemic inflammatory response syndrome

Indexed keywords

C REACTIVE PROTEIN; PROCALCITONIN; UROKINASE RECEPTOR;

ADULT; ARTICLE; BACTEREMIA; BLOOD SAMPLING; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FATALITY; FEMALE; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; PNEUMONIA; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; SENSITIVITY AND SPECIFICITY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; URINARY TRACT INFECTION;

ADULT; BACTEREMIA; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCITONIN; FEMALE; HUMANS; MALE; MIDDLE AGED; PNEUMONIA; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROTEIN PRECURSORS; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; URINARY TRACT INFECTIONS;

EID: 80052943922     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2011.07.006     Document Type: Article

References (22)

1. Alberti C., Brun-Buisson C., Goodman S.V., Guidici D., Granton J., Moreno R., et al. Influence of systemic inflammatory response syndrome and sepsis on outcome of critically ill infected patients. Am J Respir Crit Care Med 2003, 168:77-84.
2. Martin G.S., Mannino D.M., Eaton S., Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003, 348:1546-1554.
3. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992, 20:864-874.
4. Carrigan S.D., Scott G., Tabrizian M. Toward resolving the challenges of sepsis diagnosis. Clin Chem 2004, 50:1301-1314.
5. Meisner M. Biomarkers of sepsis: clinically useful?. Curr Opin Crit Care 2005, 11:473-480.
6. Kofoed K., Andersen O., Kronborg G., Tvede M., Petersen J., Eugen-Olsen J., et al. Use of plasma C-reactive protein, procalcitonin, neutrophils, macrophage migration inhibitory factor, soluble urokinase-type plasminogen activator receptor, and soluble triggering receptor expressed on myeloid cells-1 in combination to diagnose infections: a prospective study. Crit Care 2007, 11:R38.
7. Wittenhagen P., Kronborg G., Weis N., Nielsen H., Obel N., Pedersen S.S., et al. The plasma level of soluble urokinase receptor is elevated in patients with Streptococcus pneumoniae bacteraemia and predicts mortality. Clin Microbiol Infect 2004, 10:409-415.
8. Mizukami I.F., Faulkner N.E., Gyetko M.R., Sitrin R.G., Todd R.F. Enzyme-linked immunoabsorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo. Blood 1995, 86:203-211.
9. Eugen-Olsen J., Gustafson P., Sidenius N., Fischer T.K., Parner J., Aaby P., et al. The serum level of soluble urokinase receptor is elevated in tuberculosis patients and predicts mortality during treatment: a community study from Guinea-Bissau. Int J Tuberc Lung Dis 2002, 6:686-692.
10. Andersen O., Eugen-Olsen J., Kofoed K., Iversen J., Haugaard S.B. Soluble urokinase plasminogen activator receptor is a marker of dysmetabolism in HIV-infected patients receiving highly active antiretroviral therapy. J Med Virol 2008, 80:209-216.
11. Yilmaz G., Mentese A., Kaya S., Uzun A., Karahan S.C., Koksal I. The diagnostic and prognostic significance of soluble urokinase plasminogen activator receptor in Crimean-Congo hemorrhagic fever. J Clin Virol 2011, 50:209-211.
12. Florquin S., van den Berg J.G., Olszyna D.P., Claessen N., Opal S.M., Weening J.J., et al. Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia. Kidney Int 2001, 59:2054-2061.
13. Winkler F., Kastenbauer S., Koedel U., Pfister H.W. Role of the urokinase plasminogen activator system in patients with bacterial meningitis. Neurology 2002, 59:1350-1355.
14. Huttunen R., Syrjänen J., Vuento R., Hurme M., Huhtala H., Laine J., et al. Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study. J Intern Med 2011, 270:32-40.
15. Castelli G.P., Pognani C., Meisner M., Stuani A., Bellomi D., Sgarbi L. Procalcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction. Crit Care 2004, 8:234-242.
16. Mokart D., Merlin M., Sannini A., Brun J.P., Delpero J.R., Houvenaeghel G., et al. Procalcitonin, interleukin 6 and systemic inflammatory response syndrome (SIRS): early markers of postoperative sepsis after major surgery. Br J Anaesth 2005, 94:767-773.
17. von Lilienfeld-Toal M., Dietrich M.P., Glasmacher A., Lehmann L., Breig P., Hahn C., et al. Markers of bacteremia in febrile neutropenic patients with hematological malignancies: procalcitonin and IL-6 are more reliable than C-reactive protein. Eur J Clin Microbiol Infect Dis 2004, 23:539-544.
18. Harbarth S., Holeckova K., Froidevaux C., Pittet D., Ricou B., Grau G.E., et al. Geneva Sepsis Network. Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001, 164:396-402.
19. Becker K.L., Snider R., Nylen E.S. Procalcitonin assay in systemic inflammation, infection, and sepsis: clinical utility and limitations. Crit Care Med 2008, 36:941-952.
20. Gibot S., Kolopp-Sarda M.N., Béné M.C., Cravoisy A., Levy B., Faure G.C., et al. Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis. Ann Intern Med 2004, 141:9-15.
21. Brunkhorst F.M., Wegscheider K., Forycki Z.F., Brunkhorst R. Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis, and septic shock. Intensive Care Med 2000, 26:148-152.
22. Benoist J.F., Mimoz O., Assicot M. Procalcitonin in severe trauma. Ann Biol Clin Paris 1998, 56:571-574.