Porous membrane with reverse gradients of PDGF-BB and BMP-2 for tendon-to-bone repair: In vitro evaluation on adipose-derived stem cell differentiation

Acta Biomaterialia

Volumn 10, Issue 3, 2014, Pages 1272-1279

  Min, Hyun Ki ^a   Oh, Se Heang ^b   Lee, Jong Min ^c   Im, Gun Il ^c   Lee, Jin Ho ^a  

^a Hannam University   (South Korea)

^b Dankook University   (South Korea)

^c Dongguk University Ilsan Hospital   (South Korea)

Author keywords

Adipose stem cell; Differentiation; Growth factor gradient; Membrane; Tendon to bone

Indexed keywords

BONE; CYTOLOGY; GENE EXPRESSION; POLYCAPROLACTONE; POLYMERASE CHAIN REACTION; REPAIR; STEM CELLS; TENDONS;

ADIPOSE DERIVED STEM CELLS; ADIPOSE STEM CELLS; BONE MORPHOGENETIC PROTEIN-2; BONE REPAIR; DIFFERENTIATION; GROWTH FACTOR; GROWTH FACTOR GRADIENT; OSTEOGENESIS; STEM CELL DIFFERENTIATION; TENDON TO BONES;

MEMBRANES;

BONE MORPHOGENETIC PROTEIN 2; OSTEOCALCIN; PLATELET DERIVED GROWTH FACTOR BB; POLOXAMER; POLYCAPROLACTONE; TRANSCRIPTION FACTOR RUNX2; ARTIFICIAL MEMBRANE; DNA; PLATELET DERIVED GROWTH FACTOR B; PLATELET-DERIVED GROWTH FACTOR BB; POLYESTER;

ADIPOSE DERIVED STEM CELL; ARTICLE; BONE DEVELOPMENT; BONE REMODELING; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOHISTOLOGY; IN VITRO STUDY; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TENDON RECONSTRUCTION; TENDON TO BONE REPAIR; TISSUE REGENERATION; WESTERN BLOTTING; ADIPOSE TISSUE; ADULT; ARTIFICIAL MEMBRANE; BONE; CYTOLOGY; DENSITOMETRY; DRUG EFFECTS; FEMALE; METABOLISM; PATHOLOGY; STEM CELL; TENDON; WOUND HEALING;

ADIPOSE TISSUE; ADULT; BLOTTING, WESTERN; BONE AND BONES; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CELLS, CULTURED; DENSITOMETRY; DNA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANES, ARTIFICIAL; OSTEOGENESIS; POLOXAMER; POLYESTERS; POROSITY; PROTO-ONCOGENE PROTEINS C-SIS; STEM CELLS; TENDONS; WOUND HEALING;

EID: 84895067637     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.12.031     Document Type: Article

References (38)

1. S.R. Caliari, M.A. Ramirez, and A.C. Harley The development of collagen-GAG scaffold-membrane composites for tendon tissue engineering Biomaterials 32 2011 8990 8998
2. M.A. Zumstein, B. Jost, J. Hempel, J. Hodler, and C.J. Gerber The clinical and structural long-term results of open repair of massive tears of the rotator cuff J Bone Joint Surg Am 90 2008 2423 2431
3. K.L. Moffat, W.H. Sun, P.E. Pena, N.O. Chahine, and G.A. Ateshian Characterization of the structure-function relationship at the ligament-to-bone interface Proc Natl Acad Sci U S A 105 2008 7947 7952
4. S. Thomopoulos, G.M. Genin, and L.M. Galatz The development and morphogenesis of the tendon-to-bone insertion - what development can teach us about healing? J Musculoskelet Neuronal Interact 10 2010 35 45
5. S.A. Rodeo, H.G. Potter, S. Kawamura, A.S. Turner, H.J. Kim, and B.L. Atkinson Biologic augmentation of rotator cuff tendon healing using a mixture of osteoinductive growth factors: an experimental study in sheep J Bone Joint Surg Am 89 2007 2485 2497
6. M. Singh, C. Berkland, and M.S. Detamore Strategies and applications for incorporating physical and chemical signal gradients in tissue engineering Tissue Eng Part B 14 2008 341 366
7. C.G. Simon Jr., and S. Lin-Gibson Combinatorial and high-throughput screening of biomaterials Adv Mater 23 2011 369 387
8. K. Chatterjee, L. Sun, L.C. Chow, M.F. Young, and C.G. Simon Jr. Combinatorial screening of osteoblast response to 3D calcium phosphate/poly(ε-caprolactone) scaffolds using gradients and arrays Biomaterials 32 2011 1361 1369
9. Y. Yang, D. Bolikal, M.L. Becker, J. Kohn, D.N. Zeiger, and C.G. Simon Jr. Combinatorial polymer scaffold libraries for screening cell-biomaterial interactions in 3D Adv Mater 20 2008 2037 2043
10. L.A. Smith-Callahan, E.P. Childers, S.L. Bernard, S.D. Weiner, and M.L. Becker Maximizing phenotype constraint and ECM production in primary human chondrocytes using RGD concentration gradient hydrogels Acta Biomater 9 2013 7420 7428
11. L.A. Smith-Callahan, A.M. Ganios, E.P. Childers, S.D. Weiner, and M.L. Becker Primary human chondrocyte extracellular matrix formation and phenotype maintenance using RGD-derivatized PEGDM hydrogels possessing a continuous Young's modulus gradient Acta Biomater 9 2013 6095 6104
12. J.E. Babensee, L.V. McIntire, and A.G. Mikos Growth factor delivery for tissue engineering Pharm Res 17 2000 497 504
13. T. Boontheekul, and D.J. Mooney Protein-based signaling systems in tissue engineering Curr Opin Biotechnol 14 2003 559 565
14. E.R. Edelman, M.A. Nugent, and M.J. Karnovsky Perivascular and intravenous administration of basic fibroblast growth factor: vascular and solid organ deposition Proc Natl Acad Sci U S A 90 1993 1513 1517
15. K. Whang, D.C. Tsai, E.K. Nam, M. Aitken, S.M. Sprague, and P.K. Patel Ectopic bone formation via rhBMP-2 delivery from porous bioabsorbable polymer scaffolds J Biomed Mater Res 42 1998 491 499
16. L. Uebersax, H.P. Merkle, and L. Meinel Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells J Control Release 127 2008 12 21
17. C. Li, C. Vepari, H.J. Jin, H.J. Kim, and D.L. Kaplan Electrospun silk-BMP-2 scaffolds for bone tissue engineering Biomaterials 27 2006 3115 3124
18. G.I. Im, and J.H. Lee Repair of osteochondral defects with adipose stem cells and a dual growth factor-releasing scaffold in rabbits J Biomed Mater Res 92B 2010 552 560
19. S.H. Oh, T.H. Kim, and J.H. Lee Creating growth factor gradients in three dimensional porous matrix by centrifugation and surface immobilization Biomaterials 32 2011 8254 8260
20. S.H. Oh, I.G. Kim, J.Y. Lee, and J.H. Lee Bioactive porous beads as an injectable urethral bulking agent: their in vitro evaluation on smooth muscle cell differentiation Tissue Eng Part A 17 2011 655 664
21. Y. Tabata The importance of drug delivery systems in tissue engineering Pharm Sci Technol Today 3 2000 80 89
22. M. Kobayashi, E. Itoi, H. Minagawa, N. Miyakoshi, S. Takahashi, and Y. Tuoheti et al. Expression of growth factors in the early phase of supraspinatus tendon healing in rabbits J Shoulder Elbow Surg 15 2006 371 377
23. C.K. Hee, J.S. Dines, L.A. Solchaga, V.R. Shah, and J.O. Hollinger Regenerative tendon and ligament healing: opportunities with recombinant human platelet-derived growth factor BB-homodimer Tissue Eng Part B 18 2012 225 234
24. T. Onishi, Y. Ishidou, T. Nagamine, K. Yone, T. Imamura, and M. Kato et al. Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats Bone 22 1998 605 612
25. M.P. Bostrom, J.M. Lane, W.S. Berberian, A.A. Missri, E. Tomin, and A. Weiland et al. Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing J Orthop Res 13 1995 357 367
26. S.E. Kim, Y.P. Yun, D.H. Suh, Y.R. Kim, K. Park, and Y.D. Kwon et al. Recombinant human bone morphogenic protein-2 (Rhbmp-2) immobilization onto the surface of apatite-coated titanium significantly promotes osteoblast function and mineralization Tissue Eng Regen Med 9 2012 216 223
27. S.H. Oh, J.H. Kim, J.M. Kim, and J.H. Lee Asymmetrically porous PLGA/Pluronic F127 membrane for effective guided bone regeneration J Biomater Sci Polym Ed 17 2006 1375 1387
28. J. Yang, G. Shi, J. Bei, S. Wang, Y. Cao, and Q. Shang et al. Fabrication and surface modification of macroporous poly(l-lactic acid) and poly(l-lactic-co-glycolic acid) (70/30) cell scaffolds for human skin fibroblast cell culture J Biomed Mater Res 62 2002 438 446
29. Annual Book of ASTM Standards; 1996: ASTM D638-1.
30. P.K. Smith, A.K. Mallia, and G.T. Hermanson Colorimetric method for the assay of heparin content in immobilized heparin preparations Anal Biochem 109 1980 466 473
31. G.I. Im, Y.W. Shin, and K.B. Lee Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells? Osteoarthritis Cartilage 13 2005 845 853
32. I.R. Schmolka A review of block polymer surfactants J Am Oil Chem Soc 54 1977 110 116
33. S.H. Oh, I.K. Park, J.M. Kim, and J.H. Lee In vitro and in vivo characteristics of PCL scaffolds with pore size gradient fabricated by a centrifugation method Biomaterials 28 2007 1664 1671
34. N.P. Desai, and J.A. Hubbell Surface physical interpenetrating networks of poly(ethylene-terephthalate) and poly(ethylene oxide) with biomedical applications Macromolecules 25 1992 226 232
35. Y.I. Chung, G. Tae, and S.H. Yuk A facile method to prepare heparin-functionalized nanoparticles for controlled release of growth factors Biomaterials 27 2006 2621 2626
36. T.H. Kim, S.H. Oh, S.Y. Na, S.Y. Chun, and J.H. Lee Effect of biological/physical stimulation on guided bone regeneration through asymmetrically porous membrane J Biomed Mater Res Part A 100A 2012 1512 1520
37. B. Chen, B. Wang, W.J. Zhang, G. Zhou, Y. Cao, and W. Liu In vivo tendon engineering with skeletal muscle derived cells in a mouse model Biomaterials 33 2012 6086 6097
38. L. Wang, N.H. Dormer, L.F. Bonewald, and M.S. Detamore Osteogenic differentiation of human umbilical cord mesenchymal stromal cells in polyglycolic acid scaffolds Tissue Eng Part A 16 2010 1937 1948