Tertiary lymphoid neogenesis is a component of pulmonary lymphoid hyperplasia in patients with common variable immunodeficiency

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 2, 2014, Pages 535-542

  Maglione, Paul J ^a   Ko, Huaibin M ^a   Beasley, Mary B ^a   Strauchen, James A ^a   Cunningham Rundles, Charlotte ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

chronic lung disease; Common variable immunodeficiency; ectopic follicle; germinal center; lymphoid neogenesis; pulmonary hyperplasia

Indexed keywords

CHRONIC LUNG DISEASE; COMMON VARIABLE IMMUNODEFICIENCY; COMPUTED TOMOGRAPHY; CT; CVID; DIFFUSING CAPACITY OF THE LUNG FOR CARBON MONOXIDE; DLCO; ECTOPIC FOLLICLE; GERMINAL CENTER; GLILD; GRANULOMATOUS-LYMPHOCYTIC INTERSTITIAL LUNG DISEASE; LIP; LYMPHOCYTIC INTERSTITIAL PNEUMONIA; LYMPHOID NEOGENESIS; PLH; PULMONARY HYPERPLASIA; PULMONARY LYMPHOID HYPERPLASIA;

ADULT; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIGENS, CD; B-LYMPHOCYTES; BIOPSY; COMMON VARIABLE IMMUNODEFICIENCY; DNA-BINDING PROTEINS; FEMALE; HUMANS; HYPERPLASIA; IMMUNOGLOBULINS; IMMUNOLOGIC FACTORS; KI-67 ANTIGEN; LUNG; LUNG DISEASES; LYMPHOPROLIFERATIVE DISORDERS; MALE; MIDDLE AGED; T-LYMPHOCYTES;

EID: 84895064377     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.08.022     Document Type: Article

References (55)

1. H. Chapel, and C. Cunningham-Rundles Update in understanding common variable immunodeficiency disorders (CVIDs) and the management of patients with these conditions Br J Haematol 145 2009 709 727
2. M.A. Park, J.T. Li, J.B. Hagan, D.E. Maddox, and R.S. Abraham Common variable immunodeficiency: a new look at an old disease Lancet 372 2008 489 502
3. P.F. Yong, J.E. Thaventhiran, and B. Grimbacher "A rose is a rose is a rose," but CVID is Not CVID common variable immune deficiency (CVID), what do we know in 2011? Adv Immunol 111 2011 47 107
4. M. Lucas, M. Lee, J. Lortan, E. Lopez-Granados, S. Misbah, and H. Chapel Infection outcomes in patients with common variable immunodeficiency disorders: relationship to immunoglobulin therapy over 22 years J Allergy Clin Immunol 125 2010 1354 1360.e4
5. J.S. Orange, W.J. Grossman, R.J. Navickis, and M.M. Wilkes Impact of trough IgG on pneumonia incidence in primary immunodeficiency: a meta-analysis of clinical studies Clin Immunol 137 2010 21 30
6. P.J. Busse, S. Razvi, and C. Cunningham-Rundles Efficacy of intravenous immunoglobulin in the prevention of pneumonia in patients with common variable immunodeficiency J Allergy Clin Immunol 109 2002 1001 1004
7. C.A. Bates, M.C. Ellison, D.A. Lynch, C.D. Cool, K.K. Brown, and J.M. Routes Granulomatous-lymphocytic lung disease shortens survival in common variable immunodeficiency J Allergy Clin Immunol 114 2004 415 421
8. H. Chapel, M. Lucas, M. Lee, J. Bjorkander, D. Webster, and B. Grimbacher et al. Common variable immunodeficiency disorders: division into distinct clinical phenotypes Blood 112 2008 277 286
9. I. Quinti, A. Soresina, G. Spadaro, S. Martino, S. Donnanno, and C. Agostini et al. Long-term follow-up and outcome of a large cohort of patients with common variable immunodeficiency J Clin Immunol 27 2007 308 316
10. E.S. Resnick, E.L. Moshier, J.H. Godbold, and C. Cunningham-Rundles Morbidity and mortality in common variable immune deficiency over 4 decades Blood 119 2012 1650 1657
11. M.P. Bondioni, A. Soresina, V. Lougaris, D. Gatta, A. Plebani, and R. Maroldi Common variable immunodeficiency: computed tomography evaluation of bronchopulmonary changes including nodular lesions in 40 patients. Correlation with clinical and immunological data J Comput Assist Tomogr 34 2010 395 401
12. S. Gregersen, T.M. Aalokken, G. Mynarek, B. Fevang, A.M. Holm, and T. Ueland et al. Development of pulmonary abnormalities in patients with common variable immunodeficiency: associations with clinical and immunologic factors Ann Allergy Asthma Immunol 104 2010 503 510
13. C.M. Touw, A.A. van de Ven, P.A. de Jong, S. Terheggen-Lagro, E. Beek, and E.A. Sanders et al. Detection of pulmonary complications in common variable immunodeficiency Pediatr Allergy Immunol 21 2010 793 805
14. F.A. Hampson, A. Chandra, N.J. Screaton, A. Condliffe, D.S. Kumararatne, and A.R. Exley et al. Respiratory disease in common variable immunodeficiency and other primary immunodeficiency disorders Clin Radiol 67 2012 587 595
15. J.H. Park, and A.I. Levinson Granulomatous-lymphocytic interstitial lung disease (GLILD) in common variable immunodeficiency (CVID) Clin Immunol 134 2010 97 103
16. J.J. Swigris, G.J. Berry, T.A. Raffin, and W.G. Kuschner Lymphoid interstitial pneumonia: a narrative review Chest 122 2002 2150 2164
17. D.G. Guinee Jr. Update on nonneoplastic pulmonary lymphoproliferative disorders and related entities Arch Pathol Lab Med 134 2010 691 701
18. E.R. Fernandez Perez Granulomatous lymphocytic interstitial lung disease Immunol Allergy Clin North Am 32 2012 621 632
19. O. Ardeniz, and C. Cunningham-Rundles Granulomatous disease in common variable immunodeficiency Clin Immunol 133 2009 198 207
20. D. Bouvry, L. Mouthon, P.Y. Brillet, M. Kambouchner, J.P. Ducroix, and V. Cottin et al. Granulomatosis associated CVID: a case-control versus sarcoidosis study Eur Respir J 41 2013 115 122
21. N. Arish, R. Eldor, Y. Fellig, N. Bogot, U. Laxer, and U. Izhar et al. Lymphocytic interstitial pneumonia associated with common variable immunodeficiency resolved with intravenous immunoglobulins Thorax 61 2006 1096 1097
22. J. de Gracia, M. Vendrell, A. Alvarez, E. Pallisa, M.J. Rodrigo, and D. de la Rosa et al. Immunoglobulin therapy to control lung damage in patients with common variable immunodeficiency Int Immunopharmacol 4 2004 745 753
23. T. Scholzen, and J. Gerdes The Ki-67 protein: from the known and the unknown J Cell Physiol 182 2000 311 322
24. K. Basso, and R. Dalla-Favera BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis Adv Immunol 105 2010 193 210
25. T. Okada, S. Moriyama, and M. Kitano Differentiation of germinal center B cells and follicular helper T cells as viewed by tracking Bcl6 expression dynamics Immunol Rev 247 2012 120 132
26. N.J. Krautler, V. Kana, J. Kranich, Y. Tian, D. Perera, and D. Lemm et al. Follicular dendritic cells emerge from ubiquitous perivascular precursors Cell 150 2012 194 206
27. C.S. Park, and Y.S. Choi How do follicular dendritic cells interact intimately with B cells in the germinal centre? Immunology 114 2005 2 10
28. M.N. Koss, L. Hochholzer, J.M. Langloss, W.D. Wehunt, and A.A. Lazarus Lymphoid interstitial pneumonia: clinicopathological and immunopathological findings in 18 cases Pathology 19 1987 178 185
29. V. Popa Lymphocytic interstitial pneumonia of common variable immunodeficiency Ann Allergy 60 1988 203 206
30. X. Tian, E.S. Yi, and J.H. Ryu Lymphocytic interstitial pneumonia and other benign lymphoid disorders Semin Respir Crit Care Med 33 2012 450 461
31. M.A. Martinez Garcia, M.D. de Rojas, M.D. Nauffal Manzur, M.P. Munoz Pamplona, L. Compte Torrero, and V. Macian et al. Respiratory disorders in common variable immunodeficiency Respir Med 95 2001 191 195
32. W.J. Watts, M.B. Watts, W. Dai, J.T. Cassidy, C.M. Grum, and J.G. Weg Respiratory dysfunction in patients with common variable hypogammaglobulinemia Am Rev Respir Dis 134 1986 699 703
33. D. Detkova, J. de Gracia, S. Lopes-da-Silva, M. Vendrell, A. Alvarez, and L. Guarner et al. Common variable immunodeficiency: association between memory B cells and lung diseases Chest 131 2007 1883 1889
34. S.P. da Silva, E. Resnick, M. Lucas, J. Lortan, S. Patel, and C. Cunningham-Rundles et al. Lymphoid proliferations of indeterminate malignant potential arising in adults with common variable immunodeficiency disorders: unusual case studies and immunohistological review in the light of possible causative events J Clin Immunol 31 2011 784 791
35. G.D. Victora, and M.C. Nussenzweig Germinal centers Annu Rev Immunol 30 2012 429 457
36. D.L. Drayton, S. Liao, R.H. Mounzer, and N.H. Ruddle Lymphoid organ development: from ontogeny to neogenesis Nat Immunol 7 2006 344 353
37. T.D. Randall Bronchus-associated lymphoid tissue (BALT) structure and function Adv Immunol 107 2010 187 241
38. J.C. Edwards, L. Szczepanski, J. Szechinski, A. Filipowicz-Sosnowska, P. Emery, and D.R. Close et al. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis N Engl J Med 350 2004 2572 2581
39. S.L. Hauser, E. Waubant, D.L. Arnold, T. Vollmer, J. Antel, and R.J. Fox et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis N Engl J Med 358 2008 676 688
40. B. Serafini, B. Rosicarelli, R. Magliozzi, E. Stigliano, and F. Aloisi Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis Brain Pathol 14 2004 164 174
41. S. Takemura, A. Braun, C. Crowson, P.J. Kurtin, R.H. Cofield, and W.M. O'Fallon et al. Lymphoid neogenesis in rheumatoid synovitis J Immunol 167 2001 1072 1080
42. J. Pijpe, G.W. van Imhoff, F.K. Spijkervet, J.L. Roodenburg, G.J. Wolbink, and K. Mansour et al. Rituximab treatment in patients with primary Sjogren's syndrome: an open-label phase II study Arthritis Rheum 52 2005 2740 2750
43. S. Salomonsson, M.V. Jonsson, K. Skarstein, K.A. Brokstad, P. Hjelmstrom, and M. Wahren-Herlenius et al. Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjogren's syndrome Arthritis Rheum 48 2003 3187 3201
44. B. Glace, J.E. Gottenberg, X. Mariette, R. Philippe, B. Pereira, and T. Lequerre et al. Efficacy of rituximab in the treatment of pulmonary rheumatoid nodules: findings in 10 patients from the French AutoImmunity and Rituximab/Rheumatoid Arthritis registry (AIR/PR registry) Ann Rheum Dis 71 2012 1429 1431
45. G.J. Keir, T.M. Maher, D.M. Hansell, C.P. Denton, V.H. Ong, and S. Singh et al. Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy Eur Respir J 40 2012 641 648
46. I. Marie, S. Dominique, A. Janvresse, H. Levesque, and J.F. Menard Rituximab therapy for refractory interstitial lung disease related to antisynthetase syndrome Respir Med 106 2012 581 587
47. M.A. Swartz, and F.B. Vivino Dramatic reversal of lymphocytic interstitial pneumonitis in Sjogren's syndrome with rituximab J Clin Rheumatol 17 2011 454
48. A. Aghamohammadi, A. Allahverdi, H. Abolhassani, K. Moazzami, H. Alizadeh, and M. Gharagozlou et al. Comparison of pulmonary diseases in common variable immunodeficiency and X-linked agammaglobulinaemia Respirology 15 2010 289 295
49. A.C. Chan, and P.J. Carter Therapeutic antibodies for autoimmunity and inflammation Nat Rev Immunol 10 2010 301 316
50. P.F. Kohler, R.D. Cook, W.R. Brown, and R.L. Manguso Common variable hypogammaglobulinemia with T-cell nodular lymphoid interstitial pneumonitis and B-cell nodular lymphoid hyperplasia: different lymphocyte populations with a similar response to prednisone therapy J Allergy Clin Immunol 70 1982 299 305
51. J.N. Boursiquot, L. Gerard, M. Malphettes, C. Fieschi, L. Galicier, and D. Boutboul et al. Granulomatous disease in CVID: retrospective analysis of clinical characteristics and treatment efficacy in a cohort of 59 patients J Clin Immunol 33 2013 84 95
52. N.M. Chase, J.W. Verbsky, M.K. Hintermeyer, J.K. Waukau, A. Tomita-Mitchell, and J.T. Casper et al. Use of combination chemotherapy for treatment of granulomatous and lymphocytic interstitial lung disease (GLILD) in patients with common variable immunodeficiency (CVID) J Clin Immunol 33 2013 30 39
53. C.W. Davies, M.C. Juniper, W. Gray, F.V. Gleeson, H.M. Chapel, and R.J. Davies Lymphoid interstitial pneumonitis associated with common variable hypogammaglobulinaemia treated with cyclosporin A Thorax 55 2000 88 90
54. A. Malbran, M.C. Juri, and D.S. Fernandez Romero Common variable immunodeficiency and granulomatosis treated with infliximab Clin Immunol 134 2010 359 360
55. J.H. Lin, M. Liebhaber, R.L. Roberts, Z. Dyer, and E.R. Stiehm Etanercept treatment of cutaneous granulomas in common variable immunodeficiency J Allergy Clin Immunol 117 2006 878 882