Long-term follow-up and outcome of a large cohort of patients with common variable immunodeficiency

Journal of Clinical Immunology

Volumn 27, Issue 3, 2007, Pages 308-316

  Quinti, Isabella ^a   Soresina, Annarosa ^b   Spadaro, Giuseppe ^c   Martino, Silvana ^d   Donnanno, Simona ^a   Agostini, Carlo ^e   Claudio, Pignata ^c   Franco, Dammacco ^f   Pesce, Anna Maria ^a   Borghese, Federica ^a   Guerra, Andrea ^a   Rondelli, Roberto ^g   Plebani, Alessandro ^b   De Mattia, D ^h   Martire, B ^h   Cossu, F ^h   Schirillo G ^h   Castagnola, E ^h   Pietrogrande, M C ^h   Delle Piane, R M ^h   Putti, C ^h   Trizzino, A ^h   Amato, G M ^h   Bertolini, P ^h   Zecca, M ^h   Consolini, R ^h   Moschese, V ^h   Rossi, P ^h   Cancrini, C ^h   Cazzola, G A ^h   more..

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

^e UNIVERSITY OF PADOVA   (Italy)

^f UNIVERSITY OF BARI   (Italy)

^g UNIVERSITY OF BOLOGNA   (Italy)

^h NONE

Author keywords

Chronic lung disease; Common Variable Immunodeficiency; Intravenous immunoglobulins; Mortality; Pneumonia

Indexed keywords

IMMUNOGLOBULIN;

ACUTE OTITIS MEDIA; ADOLESCENT; ADULT; AGED; ARTICLE; CHRONIC DIARRHEA; CHRONIC LUNG DISEASE; CHRONIC SINUSITIS; COHORT ANALYSIS; COMMON VARIABLE IMMUNODEFICIENCY; CONTROLLED STUDY; FEMALE; FOLLOW UP; GRANULOMATOSIS; HUMAN; HUMORAL IMMUNITY; INCIDENCE; INFECTION; LOBAR PNEUMONIA; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRESCHOOL CHILD; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SCHOOL CHILD;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AUTOIMMUNE DISEASES; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; COMMON VARIABLE IMMUNODEFICIENCY; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULINS; IMMUNOTHERAPY; MALE; MIDDLE AGED; NEOPLASMS; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME;

EID: 34249048637     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-007-9075-1     Document Type: Article

References (35)

1. International Union of Immunological Societies: Primary immunodeficiency diseases, report of an IUIS scientific committee. Clin Exp Immunol 118(Suppl 1):1-28, 1999
2. Conley ME, Notarangelo LD, Etzioni A: Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin Immunol 93:190-197, 1999
3. Notarangelo LD, Casanova JL, Fischer A, Puck J, Rosen F, Seger R, Geha R: Primary immunodeficiency diseases: An update. J Allergy Clin Immunol 114:677-687, 2004
4. Hammarstrom L, Vorechovsky I, Webster D: Selective IgA deficiency and Common Variable Immunodeficiency. Clin Exp Immunol 120:225-231, 2000
5. Hausser C, Virelizier JL, Buriot D, Griscelli C: Common variable hypogammaglobulinemia in children. Clinical and immunologic observations in 30 patients. Am J Dis Child 137:833-837, 1983
6. Conley ME, Park CL, Douglas SD: Childhood common variable immunodeficiency with autoimmune disease. J Pediatr 108:915-922, 1986
7. Hermaszewski RA, WebsterAD: Primary hypogammaglobulinaemia: A survey of clinical manifestations and complications. Q J Med 86:31-42, 1993
8. Cunningham-Rundles C, Bodian C: Common variable immunodeficiency: Clinical and immunological features of 248 patients. Clin Immunol 92:34-48, 1999
9. Buehring I, Friedrich B, Schaaf J, Schmidt H, Ahrens P, Zielen S: Chronic sinusitis refractory to standard management in patients with humoral immunodeficiencies. Clin Exp Immunol 109:468-473, 1997
10. Kainulainen L, Varpula M, Liippo K, Svedstrom E, Nikoskelainen J, Ruuskanen O: Pulmonary abnormalities in patients with primary hypogammaglobulinemia. J Allergy Clin Immunol 104:1031-1036, 1999
11. Kalha I, Sellin JH: Common variable immunodeficiency and the gastrointestinal tract. Curr Gastroenterol Rep 6:377-383, 2004
12. Skull S, Kemp A: Treatment of hypogammaglobulinemia with intravenous immunoglobulins, 1973-1993. Arch Dis Child 74:527-530, 1996
13. Stiehm ER: Conventional therapy of primary immunodeficiency diseases. In Primary Immunodeficiency Diseases: A Molecular and Genetic Approach, HD Ochs, CIE Smith, JM Puck (eds). Oxford, Oxford University Press, 1999, pp 448-458
14. Quinti I, Pierdominici M, Marziali M, Giovannetti A, Donnanno S, Chapel H, et al.: European surveillance of immunoglobulin safety-results of initial survey of 1243 patients with primary immunodeficiencies in 16 countries. Clin Immunol 104:231-236, 2002
15. Busse PJ, Razvi S, Cunningham-Rundles C: Efficacy of intravenous immunoglobulin in the prevention of pneumonia in patients with common variable immunodeficiency. J Allergy Clin Immunol 109:1001-1004, 2002
16. Wang J, Cunningham-Rundles C: Treatment and outcome of autoimmune hematologic disease in common variable immunodeficiency (CVID). J Autoimmun 25:57-62, 2005
17. Roifman CM, Gelfand EW: Replacement therapy with high dose intravenous gammaglobulins improves chronic pulmonary disease in patients with hypogammaglobulinemia. Pediatr Infect Dis J 7:S92-S96, 1988
18. Quartier P, Debrè M, De Blic J, de Sauverzac R, Sayegh N, Jabado N, et al.: Early and prolonged intravenous immunoglobulin therapy in childhood agammaglobulinemia: A retrospective survey of 31 patients. J Pediatr 134:589-596, 1999
19. Plebani A, Soresina A, Rondelli R, Amato GM, Azzari C, Cardinale F, et al.: Clinical, immunological, and molecular analysis in a large cohort of patients with X-linked agammaglobulinemia: An Italian multicenter study. Clin Immunol 104:221-230, 2002
20. Thickett KM, Kumararatne DS, Banerjee AK, Dudley R, Stableforth DE: Common variable immune deficiency: Respiratory manifestations, pulmonary function and high-resolution CT scan findings. Q J Med 95:655-662, 2002
21. Carsetti R, Rosado MM, Donnanno S, et al.: The loss of IgM memory B cells correlates with clinical disease in common variable immunodeficiency. J Allergy Clin Immunol 115:412-417, 2005
22. Lanzavecchia A, Bernasconi N, Traggiai E, Ruprecht CR, Corti D, Sallusto F: Understanding and making use of human memory B cells. Immunol Rev 211:303-309, 2006
23. Kruetzmann S, Rosado MM, Weber H, et al.: Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen. J Exp Med 197:939-945, 2003
24. Amsden GW: Anti-inflammatory effects of macrolides-an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions? J Antimicrob Chemother 55:10-21, 2005
25. Warnatz K, Denz A, Drager R, et al.: Severe deficiency of switched memory B-cells (CD27+IgM-IgD-) in subgroups of patients with common variable immunodeficiency (CVID): A new approach to classify a heterogeneous disease. Blood 99:1544-1551, 2002
26. Warnatz K, Wehr C, Drager R, Schmidt S, Eibel H, Schlesier M, et al.: Expansion of CD19(hi)CD21(lo/neg) B cells in common variable immunodeficiency (CVID) patients with autoimmune cytopenia. Immunobiology 206:502-513, 2002
27. Ko J, Radigan L, Cunningham-Rundles C: Immune competence and switched memory B cells in common variable immunodeficiency. Clin Immunol 116:37-41, 2005
28. Alachkar H, Taubenheim N, Haeney MR, Durandy A, Arkwright PD: Memory switched B cell percentage and not serum immunoglobulin concentration is associated with clinical complications in children and adults with specific antibody deficiency and common variable immunodeficiency. Clin Immunol 120:310-318, 2006
29. Mechanic LJ, Dikman S, Cunningham-Rundles C: Granulomatous disease in common variable immunodeficiency. Ann Intern Med 127:613-617, 1997
30. Bates CA, Ellison MC, Lynch DA, Cool CD, Brown KK, Routes JM: Granulomatous-lymphocytic lung disease shortens survival in common variable immunodeficiency. J Allergy Clin Immunol 114:415-421, 2004
31. Mechanic LJ, Dikman S, Cunningham-Rundles C: Granulomatous disease in common variable immunodeficiency. Ann Intern Med 127:613-617, 1997
32. Kersey JH, Spector BD, Good RA. Primary immunodeficiency diseases and cancer: The immunodeficiency-cancer registry. Int J Cancer 15(12):333-347, 1973
33. Gompels MM, Hodges E, Lock RJ, Angus B, White H, Larkin A, et al.: Lymphoproliferative disease in antibody deficiency: A multi-centre study. Clin Exp Immunol 134:314-321, 2003
34. Mellemkjær L, Hammarström L, Andersen V, et al.: Cancer risk among patients with IgA deficiency or common variable immunodeficiency and their relatives: A combined Danish and Swedish study. Clin Exp Immunol 130:495-500, 2002
35. Ko J, Radigan L, Cunningham-Rundles C: Immune competence and switched memory B cells in common variable immunodeficiency. Clin Immunol 116:37-41, 2005