Evaluation of biodistribution and safety of adenovirus vector containing MDR1 in mice

Journal of Experimental and Clinical Cancer Research

Volumn 29, Issue 1, 2010, Pages

  Zhao, Zhenzhen ^a   Liu, Wei ^a   Su, Yuxi ^a   Zhu, Jin ^a   Zheng, Gaihuan ^a   Luo, Qing ^a   Jin, Xianqing ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; FLUOROURACIL; GLYCOPROTEIN P; HEMOGLOBIN; MULTIDRUG RESISTANCE PROTEIN 1; VINCRISTINE; VIRUS ANTIBODY; ABCB1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; BRAIN; CANCER CHEMOTHERAPY; COLON CARCINOMA; CONTROLLED STUDY; EMBRYO; ERYTHROCYTE COUNT; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTESTINE; KIDNEY; LEUKOCYTE COUNT; LIVER; LUNG; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SAFETY; SPLEEN; THROMBOCYTE COUNT; TISSUE DISTRIBUTION; ADENOVIRUS; ANIMAL; BAGG ALBINO MOUSE; DEFECTIVE VIRUS; EVALUATION; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; METHODOLOGY; TUMOR CELL LINE;

ADENOVIRIDAE; ANIMALS; ANTIBODIES, VIRAL; BONE MARROW TRANSPLANTATION; CELL LINE, TUMOR; DEFECTIVE VIRUSES; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MALE; MICE; MICE, INBRED BALB C; P-GLYCOPROTEIN; TRANSFECTION;

EID: 76749125527     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-29-1     Document Type: Article

References (28)

1. Duration of adjuvant chemotherapy for colon cancer and survival among the elderly. AI Neugut M Matasar X Wang R McBride JS Jacobson WY Tsai VR Grann DL Hershman, J Clin Oncol 2006 24 15 2368 2375 10.1200/JCO.2005.04.5005 16618946 (Pubitemid 46630669)
2. A Phase Study of Irinotecan Alternated with a Weekly Schedule of Oxaliplat, High-Dose Leucovorin and 48 Hour Infusion 5-Fluorouracil in Patients with Advanced Colorectal Cancer. R Gerardo T Aniello R Antonio C Diodoro P Carmine R Giorgio, Oncology 2004 66 371 378 10.1159/000079485 15331924
3. Combined effects of 5-fluorouracil, folinic acid and oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy. SP Prete M Turriziani MC Massara A De Rossi P Correale L De Vecchis F Torino L Bonmassar A Aquino, J Exp Clin Cancer Res 2008 27 5 12 10.1186/1756-9966-27-5 18577244
4. Phase III study comparing a semimonthly with a monthly regimen of fluorouracil and leucovorin as adjuvant treatment for stage II and III colon cancer patients: final results of GERCOR C96.1. T André E Quinaux C Louvet P Colin E Gamelin O Bouche E Achille P Piedbois N Tubiana-Mathieu A Boutan-Laroze, et al. J Clin Oncol 2007 25 24 3732 3738 10.1200/JCO.2007.12.2234 17704423
5. Gene Therapy for Breast Cancer-Review of Clinical Gene Therapy Trials for Breast Cancer and MDR1 Gene Therapy Trial in Cancer Institute Hospital. S Takahashi Y Ito K Hatake Y Sugimoto, Breast Cancer 2006 13 1 8 15 10.2325/jbcs.13.8 16518057
6. Genetic Protection of Repopulating Hematopoietic Cells with an Improved MDR1-Retrovirus Allows Administration of Intensified Chemotherapy Following Stem Cell Transplantation in Mice. C Alexander P Stefan O Wolfram RZ Axel KH Dieter K Klaus, et al. Int J Cancer 2002 98 785 792 10.1002/ijc.10206 11920652
7. Chemoprotection Effect of Multidrug Resistance 1(MDR1) Gene Transfer to Hematopoietic Progenitor Cells and Engrafted in Mice with Cancer Allows Intensified Chemotherapy. CB Guo XQ Jin, Cancer Invest 2006 24 7 659 668 10.1080/07357900600981299 17118775
8. Chemoprotection effect of retroviral vector encoding multidrug resistance 1 gene to allow intensified chemotherapy in vivo. CB Guo YC Li XQ Jin, Cancer Chemother Pharmacol 2006 58 1 40 49 10.1007/s00280-005-0144-y 16284790
9. Intra-bone marrow injection of allogeneic bone marrow cells: a powerful new strategy for treatment of intractable autoimmune diseases in MRL/lpr mice. K Taketoshi I Muneo H Hiroko I Naoya E Takashi Og Ryokei, et al. Blood 2001 97 3292 3299 10.1182/blood.V97.10.3292 11342461
10. Immunohistochemical Detection of Multidrug-Resistant Protein Expression in Retinoblastoma Treated by Primary Enucleation. MW Wilson CH Fraga CE Fuller C Rodriguez-Galindo J Mancini N Hagedorn, et al. Invest Ophthalmol Vis Sci 2006 47 1269 1273 10.1167/iovs.05-1321 16565357
11. Characterization of adenovirus p21 gene transfer, biodistribution, and immune response after local ocular deliveryin New Zealand white rabbits. SF Wen Z Chen J Nery B Faha, Experimental Eye Research 2003 77 355 365 10.1016/S0014-4835(03)00122-2 12907168
12. Optimization of multidrug resistance 1 gene transfer confers chemoprotection to human hematopoietic cells engrafted in immunodeficient mice. H Zhang Z Wen S Tan C Li S Lan J Li, Eur J Haematol 2007 78 5 432 439 10.1111/j.1600-0609.2007.00824.x 17331135
13. Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors. P Haviernik KD Bunting, Curr Gene Ther 2004 4 3 263 276 15384940
14. Molecular Mechanisms of Resistance and Toxicity Associated with Platinating Agents. CA Rabik ME Dolan, Cancer Treat Rev. 2007 33 1 9 23 10.1016/j.ctrv.2006.09.006 17084534
15. Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered in Collagen Exhibits Safety, Biodistribution, and Immunogenicity Profiles Favorable for Clinical Use. DL Gu T Nguyen AM Gonzalez MA Printz GF Pierce BA Sosnowski, et al. Mol Ther 2004 9 5 699 711 10.1016/j.ymthe.2004.02.018 15120331
16. Evaluation of Biodistribution and Safety of Adenovirus Vectors Containing Group B Fibers after Intravenous Injection into Baboons. S Ni K Bernt A Gaggar ZY Li HP Kiem A Lieber, Hum Gene Ther 2005 16 6 664 677 10.1089/hum.2005.16.664 15960598
17. Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas. E Galanis SH Okuno AG Nascimento BD Lewis RA Lee AM Oliveira, et al. Gene Therapy 2005 12 437 445 10.1038/sj.gt.3302436 15647767
18. Biological activities of a recombinant adenovirus p53(SCH 58500) administered by hepatic arterial infusion in a Phase 1 colorectal cancer trial. IA Atencio M Grace R Bordens M Fritz JA Horowitz B Hutchins, et al. Cancer Gene Therapy 2006 13 169 181 10.1038/sj.cgt.7700870 16082381
19. Distribution of marrow repopulating cells between bone marrow and spleen early after transplantation. PA Plett SM Frankovitz CM Orschell, Blood 2003 102 6 2285 2291 10.1182/blood-2002-12-3742 12775569
20. Murine hematopoietic stem cell distribution and proliferation in ablated and nonablated bone marrow transplantation. JF Zhong Y Zhan WF Anderson Y Zhao, Blood 2002 100 10 3521 3526 10.1182/blood-2002-04-1256 12393430
21. Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naive and pre-immunized mice. AN Varnavski R Calcedo M Bove G Gao JM Wilson, Gene Therapy 2005 12 427 436 10.1038/sj.gt.3302347 15647774
22. Fiber and Penton Base Capsid Modifications Yield Diminished Adenovirus Type 5 Transduction and Proinflammatory Gene Expression with Retention of Antigen-Specific Humoral Immunity. JW Schoggins E Falck-Pedersen, J Virol 2006 80 21 10634 10644 10.1128/JVI.01359-06 16943295
23. Differential biodistribution of adenoviral vector in vivo as monitored by bioluminescence imaging and quantitative polymerase chain reaction. M Johnson S Huyn J Burton M Sato L Wu, Hum Gene Ther 2006 17 12 1262 1269 10.1089/hum.2006.17.1262 17117891
24. Preclinical safety and biodistribution of Adenovirus-Based Cancer Vaccines After Intradermal Delivry. MS Plog CA Guyre BL Roberts M Goldberg JA St George MA Perricone, Hum Gene Ther 2006 17 705 716 10.1089/hum.2006.17.705 16839270
25. Comparison of gene expression efficiency and innate immune response induced by Ad vector and lipoplex. H Sakurai F Sakurai K Kawabata T Sasaki N Koizumi H Huang, et al. J Control Release 2007 117 3 430 437 10.1016/j.jconrel.2006.11.030 17239467
26. SCH 412499: biodistribution and safety of an adenovirus containing P21(WAF-1/CIP-1) following subconjunctival injection in Cynomolgus monkeys. RW Veneziale CM Bral DP Sinha RW Watkins ME Cartwright IY Rosenblum, et al. Cutan Ocul Toxicol. 2007 26 2 83 105 10.1080/15569520701212167 17612977
27. Enhancement of allogeneic hematopoietic stem cell engraftment and prevention of GVHD by intrabone marrow bone marrow transplantation plus donor lymphocyte infusion. K Nakamura M Inaba K Sugiura T Yoshimura AH Kwon Y Kamiyama, et al. Stem Cells 2004 22 125 134 10.1634/stemcells.22-2-125 14990852
28. Pilot study of MDR1 gene transfer into hematopoietic stem cells and chemoprotection in metastatic breast cancer patients. S Takahashi K Aiba Y Ito K Hatake M Nakane T Kobayashi, et al. Cancer Sci 2007 98 1609 1616 10.1111/j.1349-7006.2007.00571.x 17683514