New cyclopentaquinoline derivatives with fluorobenzoic acid induce G1 arrest and apoptosis in human lung adenocarcinoma cells

European Journal of Pharmacology

Volumn 729, Issue 1, 2014, Pages 30-36

  Olszewska, Paulina ^a   Szymański, Jacek ^a   Mikiciuk Olasik, Elzbieta ^a   Szymański, Paweł ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Acridine derivatives; Anticancer drug; Cyclopentaquinoline derivatives; DNA intercalation; Lung cancer

Indexed keywords

ACRIDINE; ALIPHATIC COMPOUND; BENZOIC ACID DERIVATIVE; CARBON; CASPASE 3; CYCLOPENTAQUINOLINE DERIVATIVE; DNA TOPOISOMERASE; FLUOROBENZOIC ACID; HYDRAZINONICOTINIC ACID; NICOTINIC ACID DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; BENZOIC ACID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CELL GROWTH; CELL SURVIVAL; DRUG MECHANISM; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MOLECULAR MECHANICS; PRIORITY JOURNAL; ADENOCARCINOMA; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; LUNG NEOPLASMS; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ADENOCARCINOMA; APOPTOSIS; BENZOIC ACID; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; LUNG NEOPLASMS; QUINOLINES;

EID: 84894600456     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.02.003     Document Type: Article

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