Inhibition of tumour spheroid-induced prometastatic intravasation gates in the lymph endothelial cell barrier by carbamazepine: Drug testing in a 3D model

Archives of Toxicology

Volumn 88, Issue 3, 2014, Pages 691-699

  Teichmann, Mathias ^a   Kretschy, Nicole ^a   Kopf, Sabine ^a   Jarukamjorn, Kanokwan ^b,c   Atanasov, Atanas G ^c   Viola, Katharina ^a   Giessrigl, Benedikt ^a   Saiko, Philipp ^a   Szekeres, Thomas ^a   Mikulits, Wolfgang ^d   Dirsch, Verena M ^c   Huttary, Nicole ^a   Krieger, Sigurd ^a   Jäger, Walter ^c   Grusch, Michael ^d   Dolznig, Helmut ^a   Krupitza, Georg ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b KHON KAEN UNIVERSITY   (Thailand)

^c UNIVERSITY OF VIENNA   (Austria)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

3D drug testing; Carbamazepine; Lymph endothelial intravasation; Migration; Tumour spheroid

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ALOX12 PROTEIN, HUMAN; ARACHIDONATE 12 LIPOXYGENASE; CARBAMAZEPINE; CARDIAC MYOSIN; CYP1A1 PROTEIN, HUMAN; CYTOCHROME P450 1A1; FOCAL ADHESION KINASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 2; MYOSIN LIGHT CHAIN PHOSPHATASE; PPP1R12A PROTEIN, HUMAN; PTK2 PROTEIN, HUMAN;

ANTAGONISTS AND INHIBITORS; COCULTURE; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECTS; DRUG SCREENING; ENDOTHELIUM CELL; HUMAN; MCF 7 CELL LINE; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; PHOSPHORYLATION; PROCEDURES;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ARACHIDONATE 12-LIPOXYGENASE; CARBAMAZEPINE; CARDIAC MYOSINS; CELL CULTURE TECHNIQUES; COCULTURE TECHNIQUES; CYTOCHROME P-450 CYP1A1; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOTHELIAL CELLS; FOCAL ADHESION KINASE 1; HUMANS; MCF-7 CELLS; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN PHOSPHATASE; NF-KAPPA B; PHOSPHORYLATION; SPHEROIDS, CELLULAR;

EID: 84894543761     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1183-5     Document Type: Article

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