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Volumn 34, Issue 3, 2014, Pages 565-570

Antiangiogenic therapy inhibits venous thrombus resolution

Author keywords

2 methoxyestradiol; Angiogenesis inhibitors; Axitinib; Thrombosis

Indexed keywords

2-METHOXYESTRADIOL; ANGIOGENESIS INHIBITORS; AXITINIB; THROMBOSIS;

EID: 84894538086     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.113.302998     Document Type: Article
Times cited : (49)

References (49)
  • 1
    • 20044383926 scopus 로고    scopus 로고
    • Deep vein thrombosis in cancer: The scale of the problem and approaches to management
    • Falanga A, Zacharski L. Deep vein thrombosis in cancer: The scale of the problem and approaches to management. Ann Oncol. 2005;16:696-701
    • (2005) Ann Oncol , vol.16 , pp. 696-701
    • Falanga, A.1    Zacharski, L.2
  • 2
    • 34247568441 scopus 로고    scopus 로고
    • Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy
    • Khorana AA, Francis CW, Culakova E, Kuderer NM, Lyman GH. Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy. J Thromb Haemost. 2007;5:632-634
    • (2007) J Thromb Haemost , vol.5 , pp. 632-634
    • Khorana, A.A.1    Francis, C.W.2    Culakova, E.3    Kuderer, N.M.4    Lyman, G.H.5
  • 4
    • 0141763549 scopus 로고    scopus 로고
    • Role of blood mononuclear cells in recanalization and vascularization of thrombi: Past, present, and future
    • Moldovan NI, Asahara T. Role of blood mononuclear cells in recanalization and vascularization of thrombi: Past, present, and future. Trends Cardiovasc Med. 2003;13:265-269
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 265-269
    • Moldovan, N.I.1    Asahara, T.2
  • 5
    • 0036995283 scopus 로고    scopus 로고
    • Quality-of-life improvement using thrombolytic therapy for iliofemoral deep venous thrombosis
    • Comerota AJ. Quality-of-life improvement using thrombolytic therapy for iliofemoral deep venous thrombosis. Rev Cardiovasc Med. 2002;3(Suppl 2):S61-S67
    • (2002) Rev Cardiovasc Med , vol.3 , Issue.SUPPL. 2
    • Comerota, A.J.1
  • 7
    • 19644385523 scopus 로고    scopus 로고
    • Endothelial progenitor cells are recruited into resolving venous thrombi
    • Modarai B, Burnand KG, Sawyer B, Smith A. Endothelial progenitor cells are recruited into resolving venous thrombi. Circulation. 2005;111:2645-2653
    • (2005) Circulation , vol.111 , pp. 2645-2653
    • Modarai, B.1    Burnand, K.G.2    Sawyer, B.3    Smith, A.4
  • 9
  • 10
    • 29144468038 scopus 로고    scopus 로고
    • Vascular endothelial growth factor naked DNA gene transfer enhances thrombus recanalization and resolution
    • Waltham M, Burnand K, Fenske C, Modarai B, Humphries J, Smith A. Vascular endothelial growth factor naked DNA gene transfer enhances thrombus recanalization and resolution. J Vasc Surg. 2005;42:1183-1189
    • (2005) J Vasc Surg , vol.42 , pp. 1183-1189
    • Waltham, M.1    Burnand, K.2    Fenske, C.3    Modarai, B.4    Humphries, J.5    Smith, A.6
  • 11
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer. 2003;3:721-732
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 12
    • 58149337448 scopus 로고    scopus 로고
    • Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736 an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1 2 3
    • Hu-Lowe DD, Zou HY, Grazzini ML, et al. Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3. Clin Cancer Res. 2008;14:7272-7283
    • (2008) Clin Cancer Res , vol.14 , pp. 7272-7283
    • Hu-Lowe, D.D.1    Zou, H.Y.2    Grazzini, M.L.3
  • 14
    • 82555173114 scopus 로고    scopus 로고
    • Multicenter, phase II study of axitinib, a selective second-generation inhibitor of vascular endothelial growth factor receptors 1 2, and 3, in patients with metastatic melanoma
    • Fruehauf J, Lutzky J, McDermott D, Brown CK, Meric JB, Rosbrook B, Shalinsky DR, Liau KF, Niethammer AG, Kim S, Rixe O. Multicenter, phase II study of axitinib, a selective second-generation inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, in patients with metastatic melanoma. Clin Cancer Res. 2011;17:7462-7469
    • (2011) Clin Cancer Res , vol.17 , pp. 7462-7469
    • Fruehauf, J.1    Lutzky, J.2    McDermott, D.3    Brown, C.K.4    Meric, J.B.5    Rosbrook, B.6    Shalinsky, D.R.7    Liau, K.F.8    Niethammer, A.G.9    Kim, S.10    Rixe, O.11
  • 17
    • 82755183572 scopus 로고    scopus 로고
    • Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
    • Rini BI, Escudier B, Tomczak P, et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial. Lancet. 2011;378:1931-1939
    • (2011) Lancet , vol.378 , pp. 1931-1939
    • Rini, B.I.1    Escudier, B.2    Tomczak, P.3
  • 18
    • 32944478893 scopus 로고    scopus 로고
    • Effect of inhibition of vascular endothelial growth factor signaling on distribution of extravasated antibodies in tumors
    • Nakahara T, Norberg SM, Shalinsky DR, Hu-Lowe DD, McDonald DM. Effect of inhibition of vascular endothelial growth factor signaling on distribution of extravasated antibodies in tumors. Cancer Res. 2006;66:1434-1445
    • (2006) Cancer Res , vol.66 , pp. 1434-1445
    • Nakahara, T.1    Norberg, S.M.2    Shalinsky, D.R.3    Hu-Lowe, D.D.4    McDonald, D.M.5
  • 19
    • 66249101249 scopus 로고    scopus 로고
    • Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors
    • Sennino B, Kuhnert F, Tabruyn SP, Mancuso MR, Hu-Lowe DD, Kuo CJ, McDonald DM. Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors. Cancer Res. 2009;69:4527-4536
    • (2009) Cancer Res , vol.69 , pp. 4527-4536
    • Sennino, B.1    Kuhnert, F.2    Tabruyn, S.P.3    Mancuso, M.R.4    Hu-Lowe, D.D.5    Kuo, C.J.6    McDonald, D.M.7
  • 21
    • 59449106047 scopus 로고    scopus 로고
    • Dominant effect of antiangiogenesis in combination therapy involving cyclophosphamide and axitinib
    • Ma J, Waxman DJ. Dominant effect of antiangiogenesis in combination therapy involving cyclophosphamide and axitinib. Clin Cancer Res. 2009;15:578-588
    • (2009) Clin Cancer Res , vol.15 , pp. 578-588
    • Ma, J.1    Waxman, D.J.2
  • 22
    • 0033739055 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and basic fibroblast growth factor are found in resolving venous thrombi
    • Waltham M, Burnand KG, Collins M, Smith A. Vascular endothelial growth factor and basic fibroblast growth factor are found in resolving venous thrombi. J Vasc Surg. 2000;32:988-996
    • (2000) J Vasc Surg , vol.32 , pp. 988-996
    • Waltham, M.1    Burnand, K.G.2    Collins, M.3    Smith, A.4
  • 24
    • 0028220858 scopus 로고
    • The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth
    • Fotsis T, Zhang Y, Pepper MS, Adlercreutz H, Montesano R, Nawroth PP, Schweigerer L. The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth. Nature. 1994;368:237-239
    • (1994) Nature , vol.368 , pp. 237-239
    • Fotsis, T.1    Zhang, Y.2    Pepper, M.S.3    Adlercreutz, H.4    Montesano, R.5    Nawroth, P.P.6    Schweigerer, L.7
  • 26
    • 49349109477 scopus 로고    scopus 로고
    • HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model
    • Chen W, Jadhav V, Tang J, Zhang JH. HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model. Neurobiol Dis. 2008;31:433-441
    • (2008) Neurobiol Dis , vol.31 , pp. 433-441
    • Chen, W.1    Jadhav, V.2    Tang, J.3    Zhang, J.H.4
  • 29
  • 30
    • 44449135859 scopus 로고    scopus 로고
    • Thromboembolic risk associated with use of angiogenesis inhibitors used for the treatment of cancers
    • Drouet L. [Thromboembolic risk associated with use of angiogenesis inhibitors used for the treatment of cancers]. Pathol Biol (Paris). 2008;56:195-204
    • (2008) Pathol Biol (Paris , vol.56 , pp. 195-204
    • Drouet, L.1
  • 31
    • 0037448801 scopus 로고    scopus 로고
    • Failure of thrombus to resolve in urokinase-Type plasminogen activator gene-knockout mice: Rescue by normal bone marrow-derived cells
    • Singh I, Burnand KG, Collins M, Luttun A, Collen D, Boelhouwer B, Smith A. Failure of thrombus to resolve in urokinase-Type plasminogen activator gene-knockout mice: Rescue by normal bone marrow-derived cells. Circulation. 2003;107:869-875
    • (2003) Circulation , vol.107 , pp. 869-875
    • Singh, I.1    Burnand, K.G.2    Collins, M.3    Luttun, A.4    Collen, D.5    Boelhouwer, B.6    Smith, A.7
  • 32
    • 84882254739 scopus 로고    scopus 로고
    • Magnetic resonance T1 relaxation time of venous thrombus is determined by iron processing and predicts susceptibility to lysis
    • Saha P, Andia ME, Modarai B, et al. Magnetic resonance T1 relaxation time of venous thrombus is determined by iron processing and predicts susceptibility to lysis. Circulation. 2013;128:729-736
    • (2013) Circulation , vol.128 , pp. 729-736
    • Saha, P.1    Andia, M.E.2    Modarai, B.3
  • 37
    • 0029929716 scopus 로고    scopus 로고
    • The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis
    • Clauss M, Weich H, Breier G, Knies U, Röckl W, Waltenberger J, Risau W. The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem. 1996;271:17629-17634
    • (1996) J Biol Chem , vol.271 , pp. 17629-17634
    • Clauss, M.1    Weich, H.2    Breier, G.3    Knies, U.4    Röckl, W.5    Waltenberger, J.6    Risau, W.7
  • 38
    • 38549130968 scopus 로고    scopus 로고
    • The molecular basis of VEGFR-1 signal transduction pathways in primary human monocytes
    • Tchaikovski V, Fellbrich G, Waltenberger J. The molecular basis of VEGFR-1 signal transduction pathways in primary human monocytes. Arterioscler Thromb Vasc Biol. 2008;28:322-328
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 322-328
    • Tchaikovski, V.1    Fellbrich, G.2    Waltenberger, J.3
  • 41
    • 48349129069 scopus 로고    scopus 로고
    • Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
    • Tammela T, Zarkada G, Wallgard E, et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature. 2008;454:656-660
    • (2008) Nature , vol.454 , pp. 656-660
    • Tammela, T.1    Zarkada, G.2    Wallgard, E.3
  • 43
    • 70349473165 scopus 로고    scopus 로고
    • Potential vascular actions of 2-methoxyestradiol
    • Dubey RK, Jackson EK. Potential vascular actions of 2-methoxyestradiol. Trends Endocrinol Metab. 2009;20:374-379
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 374-379
    • Dubey, R.K.1    Jackson, E.K.2
  • 44
    • 0030949341 scopus 로고    scopus 로고
    • 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: Possible role for stress-Activated protein kinase signaling pathway and Fas expression
    • Yue TL, Wang X, Louden CS, Gupta S, Pillarisetti K, Gu JL, Hart TK, Lysko PG, Feuerstein GZ. 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: Possible role for stress-Activated protein kinase signaling pathway and Fas expression. Mol Pharmacol. 1997;51:951-962
    • (1997) Mol Pharmacol , vol.51 , pp. 951-962
    • Yue, T.L.1    Wang, X.2    Louden, C.S.3    Gupta, S.4    Pillarisetti, K.5    Gu, J.L.6    Hart, T.K.7    Lysko, P.G.8    Feuerstein, G.Z.9
  • 47
    • 0043156081 scopus 로고    scopus 로고
    • Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor
    • Selvaraj SK, Giri RK, Perelman N, Johnson C, Malik P, Kalra VK. Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. Blood. 2003;102:1515-1524
    • (2003) Blood , vol.102 , pp. 1515-1524
    • Selvaraj, S.K.1    Giri, R.K.2    Perelman, N.3    Johnson, C.4    Malik, P.5    Kalra, V.K.6
  • 48
    • 0034636835 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A-induced chemotaxis of monocytes is attenuated in patients with diabetes mellitus: A potential predictor for the individual capacity to develop collaterals
    • Waltenberger J, Lange J, Kranz A. Vascular endothelial growth factor-A-induced chemotaxis of monocytes is attenuated in patients with diabetes mellitus: A potential predictor for the individual capacity to develop collaterals. Circulation. 2000;102:185-190
    • (2000) Circulation , vol.102 , pp. 185-190
    • Waltenberger, J.1    Lange, J.2    Kranz, A.3
  • 49
    • 56649123212 scopus 로고    scopus 로고
    • Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-Analysis
    • Nalluri SR, Chu D, Keresztes R, Zhu X, Wu S. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-Analysis. JAMA. 2008;300:2277-2285
    • (2008) JAMA , vol.300 , pp. 2277-2285
    • Nalluri, S.R.1    Chu, D.2    Keresztes, R.3    Zhu, X.4    Wu, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.